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Time-Resolved Freely Dissolved Concentrations of Semivolatile and Hydrophobic Test Chemicals in In Vitro AssaysMeasuring High Losses and Crossover by Headspace Solid-Phase Microextraction

Chemical research in toxicology, 2019-09, Vol.32 (9), p.1780-1790

2019

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Biokinetics in repeated-dosing in vitro drug toxicity studies

Toxicology in vitro, 2015-12, Vol.30 (1), p.217-224

2015

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Dose metric considerations in in vitro assays to improve quantitative in vitro – in vivo dose extrapolations

Toxicology (Amsterdam), 2015-06, Vol.332, p.30-40

2015

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Using in vitro data to derive acceptable exposure levels: A case study on PBDE developmental neurotoxicity

Environment international, 2024-01, Vol.183, p.108411-108411, Article 108411

2024

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Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Molecules (Basel, Switzerland), 2023-01, Vol.28 (2), p.621

2023

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Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

Frontiers in pharmacology, 2023-09, Vol.14, p.1248882-1248882

2023

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Development of a Partition-Controlled Dosing System for Cell Assays

Chemical research in toxicology, 2010-11, Vol.23 (11), p.1806-1814

2010

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HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity

Toxics (Basel), 2021-12, Vol.10 (1), p.1

2021

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Application of the Adverse Outcome Pathway Concept to In Vitro Nephrotoxicity Assessment: Kidney Injury due to Receptor-Mediated Endocytosis and Lysosomal Overload as a Case Study

Frontiers in toxicology, 2022-04, Vol.4, p.864441-864441

2022

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Dynamic Mass Balance Modeling for Chemical Distribution Over Time in In Vitro Systems With Repeated Dosing

Frontiers in toxicology, 2022-08, Vol.4, p.911128-911128

2022

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Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models

Toxicology in vitro, 2021-06, Vol.73, p.105133, Article 105133

2021

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The influence of modes of action and physicochemical properties of chemicals on the correlation between in vitro and acute fish toxicity data

Toxicology in vitro, 2009-10, Vol.23 (7), p.1372-1379

2009

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Use of Physiologically Based Kinetic Modeling to Predict Deoxynivalenol Metabolism and Its Role in Intestinal Inflammation and Bile Acid Kinetics in Humans

Journal of agricultural and food chemistry, 2024-01, Vol.72 (1), p.761-772

2024

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Integrating In Vitro Data and Physiologically Based Kinetic Modeling to Predict and Compare Acute Neurotoxic Doses of Saxitoxin in Rats, Mice, and Humans

Environmental science & technology, 2023-08, Vol.57 (30), p.10974-10984

2023

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Vipers of Major clinical relevance in Europe: Taxonomy, venom composition, toxicology and clinical management of human bites

Toxicology (Amsterdam), 2021-04, Vol.453, p.152724, Article 152724

2021

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Bioaccumulation Assessment Using Predictive Approaches

Integrated environmental assessment and management, 2009-09, Vol.5 (4), p.577-597

2009

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The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models

Toxicology (Amsterdam), 2023-02, Vol.485, p.153411, Article 153411

2023

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Acetylcholinesterase Inhibition in Rats and Humans Following Acute Fenitrothion Exposure Predicted by Physiologically Based Kinetic Modeling-Facilitated Quantitative In Vitro to In Vivo Extrapolation

Environmental science & technology, 2023-12, Vol.57 (49), p.20521-20531

2023

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An integrative approach to define chemical exposure threshold limits for endangered sea turtles

Journal of hazardous materials, 2021-10, Vol.420, p.126512-126512, Article 126512

2021

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A regression-based QSAR-model to predict acute toxicity of aromatic chemicals in tadpoles of the Japanese brown frog (Rana japonica): Calibration, validation, and future developments to support risk assessment of chemicals in amphibians

The Science of the total environment, 2022-07, Vol.830, p.154795-154795, Article 154795

2022

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Applicability of generic PBK modelling in chemical hazard assessment: A case study with IndusChemFate

Regulatory toxicology and pharmacology, 2022-12, Vol.136, p.105267-105267, Article 105267

2022

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Influence of in Vitro Assay Setup on the Apparent Cytotoxic Potency of Benzalkonium Chlorides

Chemical research in toxicology, 2019-06, Vol.32 (6), p.1103-1114

2019

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Application of in vitro data in physiologically-based kinetic models for quantitative in vitro-in vivo extrapolation: A case-study for baclofen

Toxicology in vitro, 2021-10, Vol.76, p.105223, Article 105223

2021

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A novel hypothesis for an alkaline phosphatase ‘rescue’ mechanism in the hepatic acute phase immune response

Biochimica et biophysica acta, 2013-12, Vol.1832 (12), p.2044-2056

2013

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The role of receptor‐mediated activities of 4‐ and 5‐ring unsubstituted and methylated polycyclic aromatic hydrocarbons (PAHs) in developmental toxicity

Journal of applied toxicology, 2023-06, Vol.43 (6), p.845-861

2023

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Time-Resolved Freely Dissolved Concentrations of Semivolatile and Hydrophobic Test Chemicals in In Vitro AssaysMeasuring High Losses and Crossover by Headspace Solid-Phase Microextraction

Biokinetics in repeated-dosing in vitro drug toxicity studies

Dose metric considerations in in vitro assays to improve quantitative in vitro – in vivo dose extrapolations

Using in vitro data to derive acceptable exposure levels: A case study on PBDE developmental neurotoxicity

Drug Metabolism of Hepatocyte-like Organoids and Their Applicability in In Vitro Toxicity Testing

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

Development of a Partition-Controlled Dosing System for Cell Assays

HiPSC-Derived Hepatocyte-like Cells Can Be Used as a Model for Transcriptomics-Based Study of Chemical Toxicity

Application of the Adverse Outcome Pathway Concept to In Vitro Nephrotoxicity Assessment: Kidney Injury due to Receptor-Mediated Endocytosis and Lysosomal Overload as a Case Study

Dynamic Mass Balance Modeling for Chemical Distribution Over Time in In Vitro Systems With Repeated Dosing

Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models

The influence of modes of action and physicochemical properties of chemicals on the correlation between in vitro and acute fish toxicity data

Use of Physiologically Based Kinetic Modeling to Predict Deoxynivalenol Metabolism and Its Role in Intestinal Inflammation and Bile Acid Kinetics in Humans

Integrating In Vitro Data and Physiologically Based Kinetic Modeling to Predict and Compare Acute Neurotoxic Doses of Saxitoxin in Rats, Mice, and Humans

Vipers of Major clinical relevance in Europe: Taxonomy, venom composition, toxicology and clinical management of human bites

Bioaccumulation Assessment Using Predictive Approaches

The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models

Acetylcholinesterase Inhibition in Rats and Humans Following Acute Fenitrothion Exposure Predicted by Physiologically Based Kinetic Modeling-Facilitated Quantitative In Vitro to In Vivo Extrapolation

An integrative approach to define chemical exposure threshold limits for endangered sea turtles

A regression-based QSAR-model to predict acute toxicity of aromatic chemicals in tadpoles of the Japanese brown frog (Rana japonica): Calibration, validation, and future developments to support risk assessment of chemicals in amphibians

Applicability of generic PBK modelling in chemical hazard assessment: A case study with IndusChemFate

Influence of in Vitro Assay Setup on the Apparent Cytotoxic Potency of Benzalkonium Chlorides

Application of in vitro data in physiologically-based kinetic models for quantitative in vitro-in vivo extrapolation: A case-study for baclofen

A novel hypothesis for an alkaline phosphatase ‘rescue’ mechanism in the hepatic acute phase immune response

The role of receptor‐mediated activities of 4‐ and 5‐ring unsubstituted and methylated polycyclic aromatic hydrocarbons (PAHs) in developmental toxicity

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