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Therapie mit Opioiden bei Patienten mit Leberzirrhose

Therapeutische Umschau, 2020-05, Vol.77 (1), p.14-19

Krähenbühl, Stephan

2020

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Importance of the skeletal muscle carnitine stores in fuel selection

The Journal of physiology, 2017-09, Vol.595 (17), p.5727-5728

Krahenbuhl, Stephan

2017

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Rats with Long-Term Cholestasis Have a Decreased Cytosolic but Maintained Mitochondrial Hepatic CoA Pool

International journal of molecular sciences, 2023-02, Vol.24 (5), p.4365

2023

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Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents

Toxicological sciences, 2017-05, Vol.157 (1), p.183-195

2017

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Effect of protein binding on the pharmacokinetics of the six substrates in the Basel phenotyping cocktail in healthy subjects and patients with liver cirrhosis

European journal of pharmaceutical sciences, 2024-11, Vol.202, p.106885, Article 106885

2024

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Effect of deglucuronidation on the results of the Basel phenotyping cocktail

British journal of clinical pharmacology, 2021-12, Vol.87 (12), p.4608-4618

2021

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C2C12 myoblasts are more sensitive to the toxic effects of simvastatin than myotubes and show impaired proliferation and myotube formation

Biochemical pharmacology, 2021-08, Vol.190, p.114649, Article 114649

2021

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Unmet Needs in LDL-C Lowering: When Statins Won’t Do

Drugs (New York, N.Y.), 2016-08, Vol.76 (12), p.1175-1190

2016

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mTORC2 is an important target for simvastatin-associated toxicity in C2C12 cells and mouse skeletal muscle – Roles of Rap1 geranylgeranylation and mitochondrial dysfunction

Biochemical pharmacology, 2021-10, Vol.192, p.114750, Article 114750

2021

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Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel PhenotypingCocktail Differently

Clinical pharmacokinetics, 2022-07, Vol.61 (7), p.1039-1055

2022

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The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells

Toxicology in vitro, 2017-08, Vol.42, p.337-347

2017

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Pharmacological profile of mephedrone analogs and related new psychoactive substances

Neuropharmacology, 2018-05, Vol.134 (Pt A), p.4-12

2018

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Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms

Biochemical pharmacology, 2020-07, Vol.177, p.113860, Article 113860

2020

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Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones

Toxicology (Amsterdam), 2017-07, Vol.387, p.57-66

2017

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Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines

Journal of applied toxicology, 2018-03, Vol.38 (3), p.418-431

2018

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Development and validation of an LC-MS/MS method for the analysis of ivermectin in plasma, whole blood, and dried blood spots using a fully automatic extraction system

Journal of pharmaceutical and biomedical analysis, 2019-08, Vol.172, p.18-25

2019

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Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia: A nested case-control analysis

Diabetes care, 2008-11, Vol.31 (11), p.2086-2091

2008

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Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts

Toxicology (Amsterdam), 2019-10, Vol.426, p.152281

2019

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The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis

Clinical pharmacokinetics, 2023-08, Vol.62 (8), p.1141-1155

2023

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Drug-related problems in hospitals : A review of the recent literature

Drug safety, 2007-01, Vol.30 (5), p.379-407

2007

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Toxicity of metamizole on differentiating HL60 cells and human neutrophil granulocytes

Toxicology (Amsterdam), 2019-10, Vol.426, p.152254, Article 152254

2019

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Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines

Food and chemical toxicology, 2022-04, Vol.162, p.112869, Article 112869

2022

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Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug

Frontiers in pharmacology, 2018-07, Vol.9, p.774-774

2018

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Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle

Biochemical pharmacology, 2019-06, Vol.164, p.23-33

2019

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Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use

Biochemical pharmacology, 2019-06, Vol.164, p.129-138

2019

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Therapie mit Opioiden bei Patienten mit Leberzirrhose

Importance of the skeletal muscle carnitine stores in fuel selection

Rats with Long-Term Cholestasis Have a Decreased Cytosolic but Maintained Mitochondrial Hepatic CoA Pool

Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents

Effect of protein binding on the pharmacokinetics of the six substrates in the Basel phenotyping cocktail in healthy subjects and patients with liver cirrhosis

Effect of deglucuronidation on the results of the Basel phenotyping cocktail

C2C12 myoblasts are more sensitive to the toxic effects of simvastatin than myotubes and show impaired proliferation and myotube formation

Unmet Needs in LDL-C Lowering: When Statins Won’t Do

mTORC2 is an important target for simvastatin-associated toxicity in C2C12 cells and mouse skeletal muscle – Roles of Rap1 geranylgeranylation and mitochondrial dysfunction

Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel PhenotypingCocktail Differently

The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells

Pharmacological profile of mephedrone analogs and related new psychoactive substances

Valproic acid affects fatty acid and triglyceride metabolism in HepaRG cells exposed to fatty acids by different mechanisms

Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones

Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines

Development and validation of an LC-MS/MS method for the analysis of ivermectin in plasma, whole blood, and dried blood spots using a fully automatic extraction system

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia: A nested case-control analysis

Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts

The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis

Drug-related problems in hospitals : A review of the recent literature

Toxicity of metamizole on differentiating HL60 cells and human neutrophil granulocytes

Imatinib disturbs lysosomal function and morphology and impairs the activity of mTORC1 in human hepatocyte cell lines

Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug

Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle

Cytochrome P450 enzymes contribute to the metabolism of LSD to nor-LSD and 2-oxo-3-hydroxy-LSD: Implications for clinical LSD use

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