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Antibody display technologies: selecting the cream of the crop

Biological chemistry, 2022-04, Vol.403 (5-6), p.455-477

2022

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Greatest Hits-Innovative Technologies for High Throughput Identification of Bispecific Antibodies

International journal of molecular sciences, 2020-09, Vol.21 (18), p.6551

2020

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Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of 'Almost Natural' Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection

Frontiers in immunology, 2022-01, Vol.12, p.801368-801368

2022

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Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma

Frontiers in immunology, 2019-08, Vol.10, p.1892-1892

2019

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Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform

mAbs, 2020-01, Vol.12 (1), p.1812210

2020

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Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities

mAbs, 2022, Vol.14 (1), p.2018960-2018960

2022

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A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

mAbs, 2023-12, Vol.15 (1), p.2261149-2261149

2023

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Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format

Frontiers in immunology, 2023-10, Vol.14, p.1238313-1238313

2023

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A Generic Approach for Miniaturized Unbiased High-Throughput Screens of Bispecific Antibodies and Biparatopic Antibody-Drug Conjugates

International journal of molecular sciences, 2024-02, Vol.25 (4), p.2097

2024

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REAL-Select: full-length antibody display and library screening by surface capture on yeast cells

PloS one, 2014-12, Vol.9 (12), p.e114887-e114887

2014

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Engineering hydrophobicity and manufacturability for optimized biparatopic antibody-drug conjugates targeting c-MET

mAbs, 2024, Vol.16 (1), p.2302386-2302386

2024

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Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

Frontiers in immunology, 2021-10, Vol.12, p.742418-742418

2021

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Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers

mAbs, 2024, Vol.16 (1), p.2315640-2315640

2024

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A novel one-step approach for the construction of yeast surface display Fab antibody libraries

Microbial cell factories, 2018-01, Vol.17 (1), p.3-3, Article 3

2018

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Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition

mAbs, 2023, Vol.15 (1), p.2236265-2236265

2023

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Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies

Frontiers in immunology, 2020-11, Vol.11, p.560244-560244

2020

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Single-Cell B-Cell Sequencing to Generate Natively Paired scFab Yeast Surface Display Libraries

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2681, p.175

2023

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Streamlined Data Analysis Pipeline for Deep Sequence-Coupled Biopanning Identification of Pathogen-Specific Antibody Responses in Serum

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2681, p.399

2023

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AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study

Frontiers in molecular biosciences, 2023-09, Vol.10, p.1249247

2023

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Isolation of Antigen-Specific VHH Single-Domain Antibodies by Combining Animal Immunization with Yeast Surface Display

Methods in molecular biology (Clifton, N.J.), 2020-01, Vol.2070, p.173

2020

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Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates

The Journal of biological chemistry, 2016-11, Vol.291 (48), p.25106-25119

2016

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Engineering IgG-Like Bispecific Antibodies—An Overview

Antibodies (Basel), 2018-08, Vol.7 (3), p.28

2018

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Rapid Generation of Chicken Immune Libraries for Yeast Surface Display

Methods in molecular biology (Clifton, N.J.), 2020-01, Vol.2070, p.289

2020

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A novel platform technology for the generation of fully human bispecific antibodies

New biotechnology, 2016-07, Vol.33, p.S48-S48

Krah, Simon

2016

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Antibody Phage Display: Antibody Selection in Solution Using Biotinylated Antigens

Methods in molecular biology (Clifton, N.J.), 2020-01, Vol.2070, p.143

2020

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Antibody display technologies: selecting the cream of the crop

Greatest Hits-Innovative Technologies for High Throughput Identification of Bispecific Antibodies

Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of 'Almost Natural' Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection

Dual Function pH Responsive Bispecific Antibodies for Tumor Targeting and Antigen Depletion in Plasma

Biophysical and biochemical characterization of a VHH-based IgG-like bi- and trispecific antibody platform

Beyond bispecificity: Controlled Fab arm exchange for the generation of antibodies with multiple specificities

A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

Cattle-derived knob paratopes grafted onto peripheral loops of the IgG1 Fc region enable the generation of a novel symmetric bispecific antibody format

A Generic Approach for Miniaturized Unbiased High-Throughput Screens of Bispecific Antibodies and Biparatopic Antibody-Drug Conjugates

REAL-Select: full-length antibody display and library screening by surface capture on yeast cells

Engineering hydrophobicity and manufacturability for optimized biparatopic antibody-drug conjugates targeting c-MET

Milking the Cow: Cattle-Derived Chimeric Ultralong CDR-H3 Antibodies and Their Engineered CDR-H3-Only Knobbody Counterparts Targeting Epidermal Growth Factor Receptor Elicit Potent NK Cell-Mediated Cytotoxicity

Impact of antibody architecture and paratope valency on effector functions of bispecific NKp30 x EGFR natural killer cell engagers

A novel one-step approach for the construction of yeast surface display Fab antibody libraries

Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibition

Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies

Single-Cell B-Cell Sequencing to Generate Natively Paired scFab Yeast Surface Display Libraries

Streamlined Data Analysis Pipeline for Deep Sequence-Coupled Biopanning Identification of Pathogen-Specific Antibody Responses in Serum

AI/ML combined with next-generation sequencing of VHH immune repertoires enables the rapid identification of de novo humanized and sequence-optimized single domain antibodies: a prospective case study

Isolation of Antigen-Specific VHH Single-Domain Antibodies by Combining Animal Immunization with Yeast Surface Display

Balancing Selectivity and Efficacy of Bispecific Epidermal Growth Factor Receptor (EGFR) × c-MET Antibodies and Antibody-Drug Conjugates

Engineering IgG-Like Bispecific Antibodies—An Overview

Rapid Generation of Chicken Immune Libraries for Yeast Surface Display

A novel platform technology for the generation of fully human bispecific antibodies

Antibody Phage Display: Antibody Selection in Solution Using Biotinylated Antigens

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