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HDAC2: a critical factor in health and disease

Trends in pharmacological sciences (Regular ed.), 2009-12, Vol.30 (12), p.647-655

Krämer, Oliver H

2009

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Concepts to Target MYC in Pancreatic Cancer

Molecular cancer therapeutics, 2016-08, Vol.15 (8), p.1792-1798

2016

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HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130

Nature communications, 2018-02, Vol.9 (1), p.764-17, Article 764

2018

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Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3454-3477

2018

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The interplay between histone deacetylases and rho kinases is important for cancer and neurodegeneration

Cytokine & growth factor reviews, 2017-10, Vol.37, p.29-45

2017

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Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia

Journal of medicinal chemistry, 2021-06, Vol.64 (12), p.8486-8509

2021

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Phosphorylation–acetylation switch in the regulation of STAT1 signaling

Molecular and cellular endocrinology, 2010-02, Vol.315 (1), p.40-48

2010

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Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis

PloS one, 2018-11, Vol.13 (11), p.e0207915-e0207915

2018

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STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2

Oncology reports, 2018-11, Vol.40 (5), p.2619-2627

2018

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RNA interference protocol to silence oncogenic drivers in leukemia cell lines

STAR protocols, 2022-09, Vol.3 (3), p.101512-101512, Article 101512

2022

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Inhibitors of the tyrosine kinases FMS-like tyrosine kinase-3 and WEE1 induce apoptosis and DNA damage synergistically in acute myeloid leukemia cells

Biomedicine & pharmacotherapy, 2024-08, Vol.177, p.117076, Article 117076

2024

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Boosting T cell immunity against cytomegalovirus: a potential strategy combating human aging and age-related diseases

Signal transduction and targeted therapy, 2023-09, Vol.8 (1), p.325-325, Article 325

2023

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Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells

Molecular oncology, 2024-08, Vol.18 (8), p.1958-1965

2024

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NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor

Cancers, 2023-07, Vol.15 (14), p.3650

2023

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The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells

Cell communication and signaling, 2024-04, Vol.22 (1), p.217-217, Article 217

2024

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Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells

Molecular oncology, 2021-12, Vol.15 (12), p.3404-3429

2021

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A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function

Cell reports (Cambridge), 2018-01, Vol.22 (2), p.497-511

2018

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Starving out brain tumors: a reprogrammed lysine catabolism serves as a novel target for glioblastoma treatment

Signal transduction and targeted therapy, 2023-10, Vol.8 (1), p.401-401, Article 401

2023

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Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line

World journal of gastroenterology : WJG, 2018-09, Vol.24 (33), p.3749-3759

2018

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PML promotes MHC class II gene expression by stabilizing the class II transactivator

The Journal of cell biology, 2012-10, Vol.199 (1), p.49-63

2012

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Acetylation of non-histone proteins modulates cellular signalling at multiple levels

The international journal of biochemistry & cell biology, 2009, Vol.41 (1), p.185-198

2009

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Histone deacetylases: salesmen and customers in the post-translational modification market

Biology of the cell, 2009-04, Vol.101 (4), p.193-205

2009

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MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

Cell cycle (Georgetown, Tex.), 2012-04, Vol.11 (8), p.1593-1602

2012

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Class 1 Histone Deacetylases and Ataxia-Telangiectasia Mutated Kinase Control the Survival of Murine Pancreatic Cancer Cells upon dNTP Depletion

Cells (Basel, Switzerland), 2021-09, Vol.10 (10), p.2520

2021

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Drugging the HDAC6–HSP90 interplay in malignant cells

Trends in pharmacological sciences (Regular ed.), 2014-10, Vol.35 (10), p.501-509

2014

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HDAC2: a critical factor in health and disease

Concepts to Target MYC in Pancreatic Cancer

HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130

Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors

The interplay between histone deacetylases and rho kinases is important for cancer and neurodegeneration

Development of HDAC Inhibitors Exhibiting Therapeutic Potential in T‑Cell Prolymphocytic Leukemia

Phosphorylation–acetylation switch in the regulation of STAT1 signaling

Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis

STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2

RNA interference protocol to silence oncogenic drivers in leukemia cell lines

Inhibitors of the tyrosine kinases FMS-like tyrosine kinase-3 and WEE1 induce apoptosis and DNA damage synergistically in acute myeloid leukemia cells

Boosting T cell immunity against cytomegalovirus: a potential strategy combating human aging and age-related diseases

Pharmacological degradation of ATR induces antiproliferative DNA replication stress in leukemic cells

NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor

The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells

Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells

A p300 and SIRT1 Regulated Acetylation Switch of C/EBPα Controls Mitochondrial Function

Starving out brain tumors: a reprogrammed lysine catabolism serves as a novel target for glioblastoma treatment

Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line

PML promotes MHC class II gene expression by stabilizing the class II transactivator

Acetylation of non-histone proteins modulates cellular signalling at multiple levels

Histone deacetylases: salesmen and customers in the post-translational modification market

MYC directs transcription of MCL1 and eIF4E genes to control sensitivity of gastric cancer cells toward HDAC inhibitors

Class 1 Histone Deacetylases and Ataxia-Telangiectasia Mutated Kinase Control the Survival of Murine Pancreatic Cancer Cells upon dNTP Depletion

Drugging the HDAC6–HSP90 interplay in malignant cells

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