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Mammalian TOR: A Homeostatic ATP Sensor

Science (American Association for the Advancement of Science), 2001-11, Vol.294 (5544), p.1102-1105

2001

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Drosophila S6 Kinase: A Regulator of Cell Size

Science (American Association for the Advancement of Science), 1999-09, Vol.285 (5436), p.2126-2129

1999

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Proliferation, but Not Growth, Blocked by Conditional Deletion of 40S Ribosomal Protein S6

Science (American Association for the Advancement of Science), 2000-06, Vol.288 (5473), p.2045-2047

2000

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Rapamycin Selectively Represses Translation of the "Polypyrimidine Tract" mRNA Family

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (10), p.4441-4445

1994

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The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

Molecular and Cellular Biology, 1996-11, Vol.16 (11), p.6242-6251

1996

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Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2

Molecular cell, 2003-06, Vol.11 (6), p.1457-1466

2003

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Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K

BioEssays, 2002-01, Vol.24 (1), p.65-71

2002

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Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

The EMBO journal, 1998-11, Vol.17 (22), p.6649-6659

1998

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Hypoinsulinaemia, glucose intolerance and diminished β-cell size in S6K1-deficient mice

Nature (London), 2000-12, Vol.408 (6815), p.994-997

2000

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Cloning of the Mitogen-Activated S6 Kinase from Rat Liver Reveals an Enzyme of the Second Messenger Subfamily

Proceedings of the National Academy of Sciences - PNAS, 1990-10, Vol.87 (19), p.7365-7369

1990

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A Single Gene Encodes Two Isoforms of the p70 S6 Kinase: Activation Upon Mitogenic Stimulation

Proceedings of the National Academy of Sciences - PNAS, 1992-05, Vol.89 (9), p.4052-4056

1992

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A stimulated S6 kinase from rat liver: identity with the mitogen activated S6 kinase of 3T3 cells

The EMBO journal, 1989-12, Vol.8 (13), p.4125-4132

1989

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Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

The Journal of biological chemistry, 1998-06, Vol.273 (24), p.14845

1998

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Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin

Biochemical journal, 2000-06, Vol.348 Pt 2 (2), p.351-358

2000

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Insulin Regulation of Insulin-like Growth Factor-binding Protein-1 Gene Expression Is Dependent on the Mammalian Target of Rapamycin, but Independent of Ribosomal S6 Kinase Activity

The Journal of biological chemistry, 2002-03, Vol.277 (12), p.9889-9895

2002

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. [Erratum: 2004 Sept. 23, v. 431, no. 7007, p. 485.]

Nature, 2004-09, Vol.431 (7005), p.200-205

2004

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Identification and early activation of a Xenopus laevis p70s6k following progesterone‐induced meiotic maturation

The EMBO journal, 1992-05, Vol.11 (5), p.1743-1749

1992

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mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

Science (American Association for the Advancement of Science), 2010-05, Vol.328 (5982), p.1172-1176

2010

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Hypothalamic mTOR Signaling Regulates Food Intake

Science (American Association for the Advancement of Science), 2006-05, Vol.312 (5775), p.927-930

2006

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The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231

Nucleic acids research, 1987-08, Vol.15 (15), p.5963-5971

1987

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Serine/threonine kinases in the propagation of the early mitogenic response

Reviews of physiology, biochemistry and pharmacology, 1992-01, Vol.119, p.123

1992

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p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis

Molecular and cellular biology, 1999-04, Vol.19 (4), p.2485

1999

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New acceptor cell for transfected genomic DNA: oncogene transfer into a mouse mammary epithelial cell line

Molecular and Cellular Biology, 1985-01, Vol.5 (1), p.268-272

1985

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The principal target of rapamycin‐induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain

The EMBO journal, 1995-11, Vol.14 (21), p.5279-5287

1995

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S6K1−/−/S6K2−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway

Molecular and Cellular Biology, 2004-04, Vol.24 (8), p.3112-3124

2004

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Mammalian TOR: A Homeostatic ATP Sensor

Drosophila S6 Kinase: A Regulator of Cell Size

Proliferation, but Not Growth, Blocked by Conditional Deletion of 40S Ribosomal Protein S6

Rapamycin Selectively Represses Translation of the "Polypyrimidine Tract" mRNA Family

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

Insulin Activation of Rheb, a Mediator of mTOR/S6K/4E-BP Signaling, Is Inhibited by TSC1 and 2

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

Hypoinsulinaemia, glucose intolerance and diminished β-cell size in S6K1-deficient mice

Cloning of the Mitogen-Activated S6 Kinase from Rat Liver Reveals an Enzyme of the Second Messenger Subfamily

A Single Gene Encodes Two Isoforms of the p70 S6 Kinase: Activation Upon Mitogenic Stimulation

A stimulated S6 kinase from rat liver: identity with the mitogen activated S6 kinase of 3T3 cells

Phosphorylation sites in the autoinhibitory domain participate in p70(s6k) activation loop phosphorylation

Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin

Insulin Regulation of Insulin-like Growth Factor-binding Protein-1 Gene Expression Is Dependent on the Mammalian Target of Rapamycin, but Independent of Ribosomal S6 Kinase Activity

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. [Erratum: 2004 Sept. 23, v. 431, no. 7007, p. 485.]

Identification and early activation of a Xenopus laevis p70s6k following progesterone‐induced meiotic maturation

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

Hypothalamic mTOR Signaling Regulates Food Intake

The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231

Serine/threonine kinases in the propagation of the early mitogenic response

p70(S6K) controls selective mRNA translation during oocyte maturation and early embryogenesis in Xenopus laevis

New acceptor cell for transfected genomic DNA: oncogene transfer into a mouse mammary epithelial cell line

The principal target of rapamycin‐induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain

S6K1−/−/S6K2−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway

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