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A Series of Halogenated Heterodimeric Inhibitors of Prostate Specific Membrane Antigen (PSMA) as Radiolabeled Probes for Targeting Prostate Cancer

Journal of medicinal chemistry, 2009-01, Vol.52 (2), p.347-357

2009

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3-(Hydroxymethyl)-Bearing Phosphatidylinositol Ether Lipid Analogues and Carbonate Surrogates Block PI3-K, Akt, and Cancer Cell Growth

Journal of medicinal chemistry, 2000-08, Vol.43 (16), p.3045-3051

2000

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Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells

British journal of cancer, 2001-11, Vol.85 (11), p.1771-1780

2001

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Novel Conformationally Constrained Tropane Analogues by 6-endo-trig Radical Cyclization and Stille Coupling − Switch of Activity toward the Serotonin and/or Norepinephrine Transporter

Journal of medicinal chemistry, 2000-05, Vol.43 (10), p.2064-2071

2000

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2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR)

The Journal of pharmacology and experimental therapeutics, 1992-09, Vol.262 (3), p.971

1992

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Chemistry, binding affinities, and behavioral properties of a new class of "antineophobic" mitochondrial DBI receptor complex (mDRC) ligands

Journal of medicinal chemistry, 1993-10, Vol.36 (20), p.2908-2920

1993

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Chemical Synthesis and Pharmacology of 6- and 7-Hydroxylated 2-Carbomethoxy-3-(p-tolyl)tropanes: Antagonism of Cocaine's Locomotor Stimulant Effects

Journal of medicinal chemistry, 2000-08, Vol.43 (17), p.3283-3294

2000

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Discovery of a Novel Dopamine Transporter Inhibitor, 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-Methylphenyl Ketone, as a Potential Cocaine Antagonist through 3D-Database Pharmacophore Searching. Molecular Modeling, Structure−Activity Relationships, and Behavioral Pharmacological Studies

Journal of medicinal chemistry, 2000-02, Vol.43 (3), p.351-360

2000

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Dual Function Glutamate-Related Ligands: Discovery of a Novel, Potent Inhibitor of Glutamate Carboxypeptidase II Possessing mGluR3 Agonist Activity

Journal of medicinal chemistry, 2000-03, Vol.43 (5), p.772-774

2000

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Synthesis and Biology of a 7-Nitro-2,1,3-benzoxadiazol-4-yl Derivative of 2-Phenylindole-3-acetamide: A Fluorescent Probe for the Peripheral-Type Benzodiazepine Receptor

Journal of medicinal chemistry, 1997-08, Vol.40 (16), p.2435-2439

1997

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Molecular Modeling Studies of the Akt PH Domain and Its Interaction with Phosphoinositides

Journal of medicinal chemistry, 2001-03, Vol.44 (6), p.898-908

2001

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Stimulation of brain steroidogenesis by 2-aryl-indole-3-acetamide derivatives acting at the mitochondrial diazepam-binding inhibitor receptor complex

The Journal of pharmacology and experimental therapeutics, 1993-10, Vol.267 (1), p.462

1993

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A Tandem Michael Addition Ring-Closure Route to the Metabotropic Receptor Ligand α-(Hydroxymethyl)glutamic Acid and Its γ-Alkylated Derivatives

Journal of organic chemistry, 2001-11, Vol.66 (22), p.7555-7559

2001

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Synthesis and Biology of the Conformationally Restricted ACPD Analogue, 2-Aminobicyclo[2.1.1]hexane-2,5-dicarboxylic Acid-I, a Potent mGluR Agonist

Journal of medicinal chemistry, 1998-05, Vol.41 (10), p.1641-1650

1998

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Chemistry and Pharmacology of the Piperidine-Based Analogues of Cocaine. Identification of Potent DAT Inhibitors Lacking the Tropane Skeleton

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1962-1969

1998

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Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. Potent Dopamine and Serotonin Reuptake Inhibitors

Journal of medicinal chemistry, 2000-03, Vol.43 (6), p.1215-1222

2000

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3-Deoxy-d-myo-inositol 1-Phosphate, 1-Phosphonate, and Ether Lipid Analogues as Inhibitors of Phosphatidylinositol-3-kinase Signaling and Cancer Cell Growth

Journal of medicinal chemistry, 1998-08, Vol.41 (18), p.3303-3306

1998

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Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine

Cell death & disease, 2012-07, Vol.3 (7), p.e340-e340

2012

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Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A

Nature structural & molecular biology, 1997-01, Vol.4 (1), p.57-63

1997

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Pharmacological and Behavioral Analysis of the Effects of Some Bivalent Ligand-Based Monoamine Reuptake Inhibitors

Journal of medicinal chemistry, 2001-05, Vol.44 (10), p.1615-1622

2001

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Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate—caged SPP

Bioorganic & medicinal chemistry letters, 1998-04, Vol.8 (7), p.711-714

1998

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An enantioselective synthesis and biobehavioral evaluation of 7-fluoro-3-( p-fluorophenyl)-2-propyltropanes

Bioorganic & medicinal chemistry letters, 2000-07, Vol.10 (13), p.1443-1446

2000

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Probing the Binding of Indolactam-V to Protein Kinase C through Site-Directed Mutagenesis and Computational Docking Simulations

Journal of medicinal chemistry, 1999-09, Vol.42 (18), p.3436-3446

1999

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Metabotropic glutamate receptor subtypes differentially influence neuronal recovery from in vitro hypoxia/hypoglycemia in rat hippocampal slices

Neuroscience, 1995, Vol.68 (4), p.989-1001

1995

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Structure-Activity Relationship Studies of N-Sulfonyl Analogs of Cocaine: Role of Ionic Interaction in Cocaine Binding

Journal of medicinal chemistry, 1994-09, Vol.37 (20), p.3440-3442

1994

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A Series of Halogenated Heterodimeric Inhibitors of Prostate Specific Membrane Antigen (PSMA) as Radiolabeled Probes for Targeting Prostate Cancer

3-(Hydroxymethyl)-Bearing Phosphatidylinositol Ether Lipid Analogues and Carbonate Surrogates Block PI3-K, Akt, and Cancer Cell Growth

Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human colorectal cancer cells

Novel Conformationally Constrained Tropane Analogues by 6-endo-trig Radical Cyclization and Stille Coupling − Switch of Activity toward the Serotonin and/or Norepinephrine Transporter

2-Aryl-3-indoleacetamides (FGIN-1): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR)

Chemistry, binding affinities, and behavioral properties of a new class of "antineophobic" mitochondrial DBI receptor complex (mDRC) ligands

Chemical Synthesis and Pharmacology of 6- and 7-Hydroxylated 2-Carbomethoxy-3-(p-tolyl)tropanes: Antagonism of Cocaine's Locomotor Stimulant Effects

Discovery of a Novel Dopamine Transporter Inhibitor, 4-Hydroxy-1-methyl-4-(4-methylphenyl)-3-piperidyl 4-Methylphenyl Ketone, as a Potential Cocaine Antagonist through 3D-Database Pharmacophore Searching. Molecular Modeling, Structure−Activity Relationships, and Behavioral Pharmacological Studies

Dual Function Glutamate-Related Ligands: Discovery of a Novel, Potent Inhibitor of Glutamate Carboxypeptidase II Possessing mGluR3 Agonist Activity

Synthesis and Biology of a 7-Nitro-2,1,3-benzoxadiazol-4-yl Derivative of 2-Phenylindole-3-acetamide: A Fluorescent Probe for the Peripheral-Type Benzodiazepine Receptor

Molecular Modeling Studies of the Akt PH Domain and Its Interaction with Phosphoinositides

Stimulation of brain steroidogenesis by 2-aryl-indole-3-acetamide derivatives acting at the mitochondrial diazepam-binding inhibitor receptor complex

A Tandem Michael Addition Ring-Closure Route to the Metabotropic Receptor Ligand α-(Hydroxymethyl)glutamic Acid and Its γ-Alkylated Derivatives

Synthesis and Biology of the Conformationally Restricted ACPD Analogue, 2-Aminobicyclo[2.1.1]hexane-2,5-dicarboxylic Acid-I, a Potent mGluR Agonist

Chemistry and Pharmacology of the Piperidine-Based Analogues of Cocaine. Identification of Potent DAT Inhibitors Lacking the Tropane Skeleton

Further SAR Studies of Piperidine-Based Analogues of Cocaine. 2. Potent Dopamine and Serotonin Reuptake Inhibitors

3-Deoxy-d-myo-inositol 1-Phosphate, 1-Phosphonate, and Ether Lipid Analogues as Inhibitors of Phosphatidylinositol-3-kinase Signaling and Cancer Cell Growth

Ceramide mediates nanovesicle shedding and cell death in response to phosphatidylinositol ether lipid analogs and perifosine

Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A

Pharmacological and Behavioral Analysis of the Effects of Some Bivalent Ligand-Based Monoamine Reuptake Inhibitors

Synthesis and evaluation of a photolyzable derivative of sphingosine 1-phosphate—caged SPP

An enantioselective synthesis and biobehavioral evaluation of 7-fluoro-3-( p-fluorophenyl)-2-propyltropanes

Probing the Binding of Indolactam-V to Protein Kinase C through Site-Directed Mutagenesis and Computational Docking Simulations

Metabotropic glutamate receptor subtypes differentially influence neuronal recovery from in vitro hypoxia/hypoglycemia in rat hippocampal slices

Structure-Activity Relationship Studies of N-Sulfonyl Analogs of Cocaine: Role of Ionic Interaction in Cocaine Binding

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