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CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

Malaria journal, 2012-08, Vol.11 (1), p.259-259, Article 259

2012

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Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice

Nanomedicine, 2014, Vol.10 (1), p.57-65

2014

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Role of specific cytochrome P450 isoforms in the conversion of phenoxypropoxybiguanide analogs in human liver microsomes to potent antimalarial dihydrotriazines

Drug metabolism and disposition, 2008-02, Vol.36 (2), p.380

2008

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Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

Malaria Research and Treatment, 2013, Vol.2013, p.769234-10

2013

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In Vitro Metabolism of Phenoxypropoxybiguanide Analogues in Human Liver Microsomes to Potent Antimalarial Dihydrotriazines

Journal of medicinal chemistry, 2005-04, Vol.48 (8), p.2805-2813

2005

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Antimalarial Activity of Novel 5-Aryl-8-Aminoquinoline Derivatives

Journal of medicinal chemistry, 2011-01, Vol.54 (1), p.131-142

2011

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Synthesis and Antimalarial Activity of 2-Guanidino-4-oxoimidazoline Derivatives

Journal of medicinal chemistry, 2011-07, Vol.54 (13), p.4523-4535

2011

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Causal Prophylactic Efficacy of Primaquine, Tafenoquine, and Atovaquone-Proguanil Against Plasmodium cynomolgi in a Rhesus Monkey Model

The Journal of parasitology, 2014-10, Vol.100 (5), p.671-673

2014

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Pharmacokinetics, Safety, and Hydrolysis of Oral Pyrroloquinazolinediamines Administered in Single and Multiple Doses in Rats

Antimicrobial Agents and Chemotherapy, 2007-08, Vol.51 (8), p.2898-2904

2007

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New imidazolidinedione derivatives as antimalarial agents

Bioorganic & medicinal chemistry, 2011-02, Vol.19 (4), p.1541-1549

2011

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Antimalarial Activities of New Guanidylimidazole and Guanidylimidazoline Derivatives

Journal of medicinal chemistry, 2011-10, Vol.54 (19), p.6634-6646

2011

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Muramic Acid Is Not Generally Present in the Human Spleen as Determined by Gas Chromatography-Tandem Mass Spectrometry

Infection and Immunity, 2002-02, Vol.70 (2), p.741-748

2002

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The elution of colistimethate sodium from polymethylmethacrylate and calcium phosphate cement beads

The American journal of orthopedics (Belle Mead, N.J.), 2012-06, Vol.41 (6), p.256

2012

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The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models

European journal of drug metabolism and pharmacokinetics, 2014-12, Vol.39 (4), p.231-236

2014

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Malaria Causal Prophylactic Activity of Imidazolidinedione Derivatives

Journal of medicinal chemistry, 2007-11, Vol.50 (24), p.6226-6231

2007

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In vitro Biotransformation, in vivo Efficacy and Pharmacokinetics of Antimalarial Chalcones

Pharmacology, 2011-01, Vol.87 (1-2), p.96-104

2011

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Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy

European journal of drug metabolism and pharmacokinetics, 2012-03, Vol.37 (1), p.17-22

2012

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Analysis of a stable halogenated derivative of muramic acid by gas chromatography–negative ion chemical ionization tandem mass spectrometry

Journal of Chromatography A, 2002-02, Vol.946 (1), p.229-238

2002

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Failure To Detect Muramic Acid in Normal Rat Tissues but Detection in Cerebrospinal Fluids from Patients with Pneumococcal Meningitis

Infection and Immunity, 2000-08, Vol.68 (8), p.4688-4698

2000

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Trace analysis of muramic acid in indoor air using an automated derivatization instrument and GC-MS(2) or GC-MS(3)

Journal of microbiological methods, 2002-09, Vol.51 (1), p.95

2002

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Trace analysis of muramic acid in indoor air using an automated derivatization instrument and GC-MS2 or GC-MS3

Journal of microbiological methods, 2002-09, Vol.51 (1), p.95-104

2002

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Lunar dust: a negative control for biomarker analyses of extraterrestrial samples?

Geochimica et cosmochimica acta, 2001-10, Vol.65 (19), p.3307-3317

2001

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Antimalarial compound identification and design: advances in the patent literature, 2000 - 2003

Expert opinion on therapeutic patents, 2004-08, Vol.14 (8), p.1125-1138

2004

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Facile synthesis of 2,4-diamino-6-alkyl- or 6-aryl-pyrimidine derivatives

Journal of heterocyclic chemistry, 2010-09, Vol.47 (5), p.1056-1061

2010

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A facile one pot synthesis of 2, 4-diamino-6-substituted s-triazine derivatives

Journal of heterocyclic chemistry, 2008-11, Vol.45 (6), p.1673-1678

2008

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CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

Nanoparticle formulations of decoquinate increase antimalarial efficacy against liver stage Plasmodium infections in mice

Role of specific cytochrome P450 isoforms in the conversion of phenoxypropoxybiguanide analogs in human liver microsomes to potent antimalarial dihydrotriazines

Formulation and Particle Size Reduction Improve Bioavailability of Poorly Water-Soluble Compounds with Antimalarial Activity

In Vitro Metabolism of Phenoxypropoxybiguanide Analogues in Human Liver Microsomes to Potent Antimalarial Dihydrotriazines

Antimalarial Activity of Novel 5-Aryl-8-Aminoquinoline Derivatives

Synthesis and Antimalarial Activity of 2-Guanidino-4-oxoimidazoline Derivatives

Causal Prophylactic Efficacy of Primaquine, Tafenoquine, and Atovaquone-Proguanil Against Plasmodium cynomolgi in a Rhesus Monkey Model

Pharmacokinetics, Safety, and Hydrolysis of Oral Pyrroloquinazolinediamines Administered in Single and Multiple Doses in Rats

New imidazolidinedione derivatives as antimalarial agents

Antimalarial Activities of New Guanidylimidazole and Guanidylimidazoline Derivatives

Muramic Acid Is Not Generally Present in the Human Spleen as Determined by Gas Chromatography-Tandem Mass Spectrometry

The elution of colistimethate sodium from polymethylmethacrylate and calcium phosphate cement beads

The use of a prodrug approach to minimize potential CNS exposure of next generation quinoline methanols while maintaining efficacy in in vivo animal models

Malaria Causal Prophylactic Activity of Imidazolidinedione Derivatives

In vitro Biotransformation, in vivo Efficacy and Pharmacokinetics of Antimalarial Chalcones

Ketotifen is an antimalarial prodrug of norketotifen with blood schizonticidal and liver-stage efficacy

Analysis of a stable halogenated derivative of muramic acid by gas chromatography–negative ion chemical ionization tandem mass spectrometry

Failure To Detect Muramic Acid in Normal Rat Tissues but Detection in Cerebrospinal Fluids from Patients with Pneumococcal Meningitis

Trace analysis of muramic acid in indoor air using an automated derivatization instrument and GC-MS(2) or GC-MS(3)

Trace analysis of muramic acid in indoor air using an automated derivatization instrument and GC-MS2 or GC-MS3

Lunar dust: a negative control for biomarker analyses of extraterrestrial samples?

Antimalarial compound identification and design: advances in the patent literature, 2000 - 2003

Facile synthesis of 2,4-diamino-6-alkyl- or 6-aryl-pyrimidine derivatives

A facile one pot synthesis of 2, 4-diamino-6-substituted s-triazine derivatives

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