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Pharmacological Profile of Difamilast, a Novel Selective Phosphodiesterase 4 Inhibitor, for Topical Treatment of Atopic Dermatitis

The Journal of pharmacology and experimental therapeutics, 2023-07, Vol.386 (1), p.45-55

2023

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Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo

Drug metabolism and disposition, 2015-08, Vol.43 (8), p.1267-1276

2015

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Activation of apoptosis inhibitor of macrophage is a sensitive diagnostic marker for NASH-associated hepatocellular carcinoma

Journal of gastroenterology, 2018-06, Vol.53 (6), p.770-779

2018

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Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis

Journal of Crohn's and colitis, 2017-01, Vol.11 (1), p.84-91

2017

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Metabolic Mechanism of Delamanid, a New Anti-Tuberculosis Drug, in Human Plasma

Drug metabolism and disposition, 2015-08, Vol.43 (8), p.1277-1283

2015

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A deep learning algorithm for sleep stage scoring in mice based on a multimodal network with fine-tuning technique

Neuroscience research, 2021-12, Vol.173, p.99-105

2021

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Genotoxicity and subchronic toxicity of a kaempferol aglycone-rich product produced from horseradish leaves

Fundamental toxicological sciences, 2022, Vol.9 (3), p.71-83

2022

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Development of Two-dimensional Template System for the Prediction of CYP2B6-mediated Reaction Sites

DRUG METABOLISM AND PHARMACOKINETICS, 2011-01, Vol.26 (4), p.309-330

2011

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Classification of patients with non‐alcoholic fatty liver disease using rapid immunoassay of serum type IV collagen compared with liver histology and other fibrosis markers

Hepatology research, 2017-02, Vol.47 (2), p.216-225

2017

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Pharmacodynamic change in plasma angiogenic proteins: a dose-escalation phase 1 study of the multi-kinase inhibitor lenvatinib

BMC cancer, 2014-07, Vol.14 (1), p.530-530, Article 530

2014

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Nationwide Database Analysis of Risk Factors Associated with Decreased Activities of Daily Living in Patients with Alzheimer’s Disease

Journal of Alzheimer's disease, 2023-01, Vol.94 (4), p.1465-1475

2023

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Nationwide database analysis of insomnia, depression, and sleeping pill prescriptions in hepatocellular carcinoma patients

Current medical research and opinion, 2022-08, Vol.38 (8), p.1333-1339

2022

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Preclinical study for antitumor mechanism of lenvatinib and clinical studies for hepatocellular carcinoma

Folia Pharmacologica Japonica, 2019, Vol.153(5), pp.242-248

2019

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Effect of olprinone on liver microstructure in rat partial liver transplantation

The Journal of surgical research, 2013-07, Vol.183 (1), p.391-396

2013

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Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinase inhibitor

Arteriosclerosis, thrombosis, and vascular biology, 1996-01, Vol.16 (1), p.28-33

1996

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Phase I Dose-Escalation Study and Biomarker Analysis of E7080 in Patients with Advanced Solid Tumors

Clinical cancer research, 2011-04, Vol.17 (8), p.2528-2537

2011

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Real-world database analysis of the characteristics and treatment patterns of patients with endometrial cancer in Japan

Current medical research and opinion, 2021-07, Vol.37 (7), p.1171-1178

2021

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Overexpression of Tissue Inhibitor of Matrix Metalloproteinase-1 Inhibits Vascular Smooth Muscle Cell Functions In Vitro and In Vivo

Circulation research, 1996-10, Vol.79 (4), p.812-820

1996

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Clinical relevance of increased serum preneoplastic antigen in hepatitis C-related hepatocellular carcinoma

World journal of gastroenterology : WJG, 2020-04, Vol.26 (13), p.1463-1473

2020

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Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human

Xenobiotica, 2021-05, Vol.51 (5), p.590-604

2021

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Comprehensive kinetic analysis and influence of reaction components for chlorzoxazone 6-hydroxylation in human liver microsomes with CYP antibodies

Xenobiotica, 2015-04, Vol.45 (4), p.353-360

2015

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α6β1 integrin induces proteasome-mediated cleavage of erbB2 in breast cancer cells

Oncogene, 2003-02, Vol.22 (6), p.831-839

2003

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Preclinical and clinical efficacy of orexin receptor antagonist Lemborexant (Dayvigo®) on insomnia patients

Folia Pharmacologica Japonica, 2021, Vol.156(2), pp.114-119

2021

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Database analysis of patients with hepatocellular carcinoma and treatment flow in early and advanced stages

Pharmacology research & perspectives, 2019-08, Vol.7 (4), p.e00486-n/a

2019

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Highlights of the 14th Japan Bioanalysis Forum Symposium

Bioanalysis, 2023-11, Vol.15 (21), p.1271-1276

2023

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Pharmacological Profile of Difamilast, a Novel Selective Phosphodiesterase 4 Inhibitor, for Topical Treatment of Atopic Dermatitis

Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo

Activation of apoptosis inhibitor of macrophage is a sensitive diagnostic marker for NASH-associated hepatocellular carcinoma

Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis

Metabolic Mechanism of Delamanid, a New Anti-Tuberculosis Drug, in Human Plasma

A deep learning algorithm for sleep stage scoring in mice based on a multimodal network with fine-tuning technique

Genotoxicity and subchronic toxicity of a kaempferol aglycone-rich product produced from horseradish leaves

Development of Two-dimensional Template System for the Prediction of CYP2B6-mediated Reaction Sites

Classification of patients with non‐alcoholic fatty liver disease using rapid immunoassay of serum type IV collagen compared with liver histology and other fibrosis markers

Pharmacodynamic change in plasma angiogenic proteins: a dose-escalation phase 1 study of the multi-kinase inhibitor lenvatinib

Nationwide Database Analysis of Risk Factors Associated with Decreased Activities of Daily Living in Patients with Alzheimer’s Disease

Nationwide database analysis of insomnia, depression, and sleeping pill prescriptions in hepatocellular carcinoma patients

Preclinical study for antitumor mechanism of lenvatinib and clinical studies for hepatocellular carcinoma

Effect of olprinone on liver microstructure in rat partial liver transplantation

Regulation of vascular smooth muscle cell migration and proliferation in vitro and in injured rat arteries by a synthetic matrix metalloproteinase inhibitor

Phase I Dose-Escalation Study and Biomarker Analysis of E7080 in Patients with Advanced Solid Tumors

Real-world database analysis of the characteristics and treatment patterns of patients with endometrial cancer in Japan

Overexpression of Tissue Inhibitor of Matrix Metalloproteinase-1 Inhibits Vascular Smooth Muscle Cell Functions In Vitro and In Vivo

Clinical relevance of increased serum preneoplastic antigen in hepatitis C-related hepatocellular carcinoma

Pharmacokinetics and metabolism of brexpiprazole, a novel serotonin-dopamine activity modulator and its main metabolite in rat, monkey and human

Comprehensive kinetic analysis and influence of reaction components for chlorzoxazone 6-hydroxylation in human liver microsomes with CYP antibodies

α6β1 integrin induces proteasome-mediated cleavage of erbB2 in breast cancer cells

Preclinical and clinical efficacy of orexin receptor antagonist Lemborexant (Dayvigo®) on insomnia patients

Database analysis of patients with hepatocellular carcinoma and treatment flow in early and advanced stages

Highlights of the 14th Japan Bioanalysis Forum Symposium

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