UB Paderborn / Katalog / Suche / in CDI

Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models

PloS one, 2024-01, Vol.19 (1), p.e0292091-e0292091

2024

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Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Scientific reports, 2017-03, Vol.7 (1), p.492-492, Article 492

2017

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Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models

Pharmacology research & perspectives, 2022-04, Vol.10 (2), p.e00938-n/a

2022

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Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms

PloS one, 2014-01, Vol.9 (1), p.e86522-e86522

2014

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Acute SGLT-2i treatment improves cardiac efficiency during myocardial ischemia independent of Na+/H+ exchanger-1

International journal of cardiology, 2022-09, Vol.363, p.138-148

2022

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Opportunities for pharmacotherapy at the intersection of metabolic syndrome and hemostasis

Current pharmaceutical biotechnology, 2011-09, Vol.12 (9), p.1463

2011

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Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1151-1156

2008

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Distinct hemodynamic responses to (pyr)apelin-13 in large animal models

American journal of physiology. Heart and circulatory physiology, 2020-04, Vol.318 (4), p.H747-H755

2020

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Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Scientific reports, 2018-10, Vol.8 (1), p.16077-1, Article 16077

2018

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The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay

The Journal of pharmacology and experimental therapeutics, 2008-06, Vol.325 (3), p.723

2008

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Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice

Pharmacological research, 2008-07, Vol.58 (1), p.45-51

2008

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The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins

The Journal of pharmacology and experimental therapeutics, 2008-02, Vol.324 (2), p.576

2008

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Prospective Identification of Biologically Active Structures by Topomer Shape Similarity Searching

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3919-3933

1999

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Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats

The Journal of pharmacology and experimental therapeutics, 2017-07, Vol.362 (1), p.108

2017

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Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension

The Journal of pharmacology and experimental therapeutics, 2004-04, Vol.309 (1), p.275

2004

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Discovery of N-Isoxazolyl Biphenylsulfonamides as Potent Dual Angiotensin II and Endothelin A Receptor Antagonists

Journal of medicinal chemistry, 2002-08, Vol.45 (18), p.3829-3835

2002

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Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice

Kidney international, 2000-01, Vol.57 (1), p.129-136

2000

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Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.171-179

2005

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Discovery of 4′-[(Imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/Angiotensin II receptor antagonists

Bioorganic & medicinal chemistry letters, 2003-03, Vol.13 (6), p.1093-1096

2003

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Characterization of atherosclerosis in LDL receptor knockout mice: macrophage accumulation correlates with rapid and sustained expression of aortic MCP-1/JE

Atherosclerosis, 2000-04, Vol.149 (2), p.323-330

2000

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Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease

Endocrine, metabolic & immune disorders drug targets, 2008-12, Vol.8 (4), p.238

2008

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Plasminogen deficiency accelerates vessel wall disease in mice predisposed to atherosclerosis

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (19), p.10335-10340

1997

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A Nonpeptide, Piperidine Renin Inhibitor Provides Renal and Cardiac Protection in Double-Transgenic Mice Expressing Human Renin and Angiotensinogen Genes

Cardiovascular drugs and therapy, 2008-12, Vol.22 (6), p.469-478

2008

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Pyrazole inhibitors of HMG-CoA reductase: An attempt to dramatically reduce synthetic complexity through minimal analog re-design

Bioorganic & medicinal chemistry letters, 2007-10, Vol.17 (20), p.5567-5572

2007

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Inhibitors of angiotensin converting enzyme decrease early atherosclerosis in hyperlipidemic hamsters. Fosinopril reduces plasma cholesterol and captopril inhibits macrophage—foam cell accumulation independently of blood pressure and plasma lipids

Atherosclerosis, 1994-07, Vol.108 (1), p.61-72

1994

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Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models

Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models

Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms

Acute SGLT-2i treatment improves cardiac efficiency during myocardial ischemia independent of Na+/H+ exchanger-1

Opportunities for pharmacotherapy at the intersection of metabolic syndrome and hemostasis

Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

Distinct hemodynamic responses to (pyr)apelin-13 in large animal models

Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay

Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice

The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins

Prospective Identification of Biologically Active Structures by Topomer Shape Similarity Searching

Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats

Novel dual action AT1 and ETA receptor antagonists reduce blood pressure in experimental hypertension

Discovery of N-Isoxazolyl Biphenylsulfonamides as Potent Dual Angiotensin II and Endothelin A Receptor Antagonists

Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice

Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics

Discovery of 4′-[(Imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/Angiotensin II receptor antagonists

Characterization of atherosclerosis in LDL receptor knockout mice: macrophage accumulation correlates with rapid and sustained expression of aortic MCP-1/JE

Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease

Plasminogen deficiency accelerates vessel wall disease in mice predisposed to atherosclerosis

A Nonpeptide, Piperidine Renin Inhibitor Provides Renal and Cardiac Protection in Double-Transgenic Mice Expressing Human Renin and Angiotensinogen Genes

Pyrazole inhibitors of HMG-CoA reductase: An attempt to dramatically reduce synthetic complexity through minimal analog re-design

Inhibitors of angiotensin converting enzyme decrease early atherosclerosis in hyperlipidemic hamsters. Fosinopril reduces plasma cholesterol and captopril inhibits macrophage—foam cell accumulation independently of blood pressure and plasma lipids

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