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Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models

PloS one, 2024-01, Vol.19 (1), p.e0292091

2024

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Acute SGLT-2i treatment improves cardiac efficiency during myocardial ischemia independent of Na+/H+ exchanger-1

International journal of cardiology, 2022-09, Vol.363, p.138-148

2022

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Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Scientific reports, 2017-03, Vol.7 (1), p.492-492, Article 492

2017

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Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody[S]

Journal of lipid research, 2015-11, Vol.56 (11), p.2124-2132

2015

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Distinct hemodynamic responses to (pyr)apelin-13 in large animal models

American journal of physiology. Heart and circulatory physiology, 2020-04, Vol.318 (4), p.H747-H755

2020

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Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Scientific reports, 2018-10, Vol.8 (1), p.16077-1, Article 16077

2018

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Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice

Pharmacological research, 2008-07, Vol.58 (1), p.45-51

2008

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Rare DEGS1 variant significantly alters de novo ceramide synthesis pathway[S]

Journal of lipid research, 2019-09, Vol.60 (9), p.1630-1639

2019

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Identification and Characterization of a Major Liver Lysophosphatidylcholine Acyltransferase

The Journal of biological chemistry, 2008-03, Vol.283 (13), p.8258-8265

2008

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Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms

PloS one, 2014-01, Vol.9 (1), p.e86522-e86522

2014

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Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models

Pharmacology research & perspectives, 2022-04, Vol.10 (2), p.e00938-n/a

2022

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Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats

The Journal of pharmacology and experimental therapeutics, 2017-07, Vol.362 (1), p.108-118

2017

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Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

Frontiers in physiology, 2020-09, Vol.11, p.543727-543727

2020

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Genome-wide Screen for Modulation of Hepatic Apolipoprotein A-I (ApoA-I) Secretion

The Journal of biological chemistry, 2013-03, Vol.288 (9), p.6386-6396

2013

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Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats

Disease models & mechanisms, 2013-03, Vol.6 (2), p.443-456

2013

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Opportunities for pharmacotherapy at the intersection of metabolic syndrome and hemostasis

Current pharmaceutical biotechnology, 2011-09, Vol.12 (9), p.1463-1480

2011

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Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (3), p.1151-1156

2008

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Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease

Endocrine, metabolic & immune disorders drug targets, 2008-12, Vol.8 (4), p.238-243

2008

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Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.171-179

2005

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Prospective Identification of Biologically Active Structures by Topomer Shape Similarity Searching

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3919-3933

1999

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The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay

The Journal of pharmacology and experimental therapeutics, 2008-06, Vol.325 (3), p.723-731

2008

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The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins

The Journal of pharmacology and experimental therapeutics, 2008-02, Vol.324 (2), p.576-586

2008

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Abstract 16840: A Novel Long-Acting CRF2 Receptor Agonist COR-1167 Improves Cardiac and Renal Function on Top of Furosemide in a Sheep Model of Pacing Induced Heart Failure

Circulation (New York, N.Y.), 2023-11, Vol.148 (Suppl_1)

2023

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Abstract 16904: Low-Dose Isoproterenol Administration in the Murine MDX Model Unmasks Progression of Duchenne-Associated Cardiomyopathy

Circulation (New York, N.Y.), 2023-11, Vol.148 (Suppl_1)

2023

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Characterization of atherosclerosis in LDL receptor knockout mice: macrophage accumulation correlates with rapid and sustained expression of aortic MCP-1/JE

Atherosclerosis, 2000-04, Vol.149 (2), p.323-330

2000

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Effect of an NHE3 inhibitor in combination with an NPT2b inhibitor on gastrointestinal phosphate absorption in Rodent models

Acute SGLT-2i treatment improves cardiac efficiency during myocardial ischemia independent of Na+/H+ exchanger-1

Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody[S]

Distinct hemodynamic responses to (pyr)apelin-13 in large animal models

Author Correction: Salt-dependent Blood Pressure in Human Aldosterone Synthase-Transgenic Mice

Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice

Rare DEGS1 variant significantly alters de novo ceramide synthesis pathway[S]

Identification and Characterization of a Major Liver Lysophosphatidylcholine Acyltransferase

Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms

Effects of pharmacological inhibition of the sodium‐dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models

Identification of 4-Aminopyrazolopyrimidine Metabolite That May Contribute to the Hypolipidemic Effects of LY2584702 in Long Evans Diet-Induced Obese Rats

Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

Genome-wide Screen for Modulation of Hepatic Apolipoprotein A-I (ApoA-I) Secretion

Bile-acid-mediated decrease in endoplasmic reticulum stress: a potential contributor to the metabolic benefits of ileal interposition surgery in UCD-T2DM rats

Opportunities for pharmacotherapy at the intersection of metabolic syndrome and hemostasis

Hepatoselectivity of statins: Design and synthesis of 4-sulfamoyl pyrroles as HMG-CoA reductase inhibitors

Further LDL cholesterol lowering through targeting PCSK9 for coronary artery disease

Dual Angiotensin II and Endothelin A Receptor Antagonists: Synthesis of 2‘-Substituted N-3-Isoxazolyl Biphenylsulfonamides with Improved Potency and Pharmacokinetics

Prospective Identification of Biologically Active Structures by Topomer Shape Similarity Searching

The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay

The Guinea pig as a preclinical model for demonstrating the efficacy and safety of statins

Abstract 16840: A Novel Long-Acting CRF2 Receptor Agonist COR-1167 Improves Cardiac and Renal Function on Top of Furosemide in a Sheep Model of Pacing Induced Heart Failure

Abstract 16904: Low-Dose Isoproterenol Administration in the Murine MDX Model Unmasks Progression of Duchenne-Associated Cardiomyopathy

Characterization of atherosclerosis in LDL receptor knockout mice: macrophage accumulation correlates with rapid and sustained expression of aortic MCP-1/JE

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