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Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies

Scientific reports, 2023-04, Vol.13 (1), p.6730-6730, Article 6730

2023

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Use of Pharmacokinetic-Pharmacodynamic Analyses To Optimize Therapy with the Systemic Antifungal Micafungin for Invasive Candidiasis or Candidemia

Antimicrobial Agents and Chemotherapy, 2011-05, Vol.55 (5), p.2113-2121

2011

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Clinical Pharmacodynamic Index Identification for Micafungin in Esophageal Candidiasis: Dosing Strategy Optimization

Antimicrobial Agents and Chemotherapy, 2013-11, Vol.57 (11), p.5714-5716

2013

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Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi

Antimicrobial agents and chemotherapy, 2017-12, Vol.61 (12)

2017

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In Vitro Activity of Isavuconazole against Opportunistic Fungal Pathogens from Two Mycology Reference Laboratories

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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Pharmacodynamics of Isavuconazole for Invasive Mold Disease: Role of Galactomannan for Real-Time Monitoring of Therapeutic Response

Clinical infectious diseases, 2017-06, Vol.64 (11), p.1557-1563

2017

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Safety, tolerability and immunogenicity of a novel 24-valent pneumococcal vaccine in toddlers: A phase 1 randomized controlled trial

Vaccine, 2024-04, Vol.42 (10), p.2560-2571

2024

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Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study)

Antimicrobial agents and chemotherapy, 2016-08, Vol.60 (8), p.4568-4576

2016

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Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis

Antimicrobial agents and chemotherapy, 2021-05, Vol.65 (6)

2021

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Safety, Tolerability, and Population Pharmacokinetics of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients

Antimicrobial agents and chemotherapy, 2021-07, Vol.65 (8), p.e0029021

2021

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Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints

Journal of antimicrobial chemotherapy, 2016-07, Vol.71 (7), p.1885-1891

2016

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Population Pharmacokinetic Modeling of VL-2397, a Novel Systemic Antifungal Agent: Analysis of a Single- and Multiple-Ascending-Dose Study in Healthy Subjects

Antimicrobial agents and chemotherapy, 2019-06, Vol.63 (6)

2019

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A Phase 3 Study of Micafungin Versus Amphotericin B Deoxycholate in Infants With Invasive Candidiasis

The Pediatric infectious disease journal, 2018-10, Vol.37 (10), p.992-998

2018

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Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6)

2017

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Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis

Antimicrobial agents and chemotherapy, 2016-05, Vol.60 (5), p.2718-2726

2016

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Pharmacodynamics of Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis

Antimicrobial agents and chemotherapy, 2019-09, Vol.63 (9)

2019

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Outcomes by MIC Values for Patients Treated with Isavuconazole or Voriconazole for Invasive Aspergillosis in the Phase 3 SECURE and VITAL Trials

Antimicrobial agents and chemotherapy, 2019-01, Vol.63 (1)

2019

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Prognostic value of galactomannan: current evidence for monitoring response to antifungal therapy in patients with invasive aspergillosis

Journal of Pharmacokinetics and Pharmacodynamics, 2017-04, Vol.44 (2), p.143-151

2017

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In vitro combination of isavuconazole with micafungin or amphotericin B deoxycholate against medically important molds

Antimicrobial agents and chemotherapy, 2014-11, Vol.58 (11), p.6934-6937

2014

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Population pharmacokinetics of micafungin and its metabolites M1 and M5 in children and adolescents

Antimicrobial agents and chemotherapy, 2015-02, Vol.59 (2), p.905-913

2015

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Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis

Antimicrobial agents and chemotherapy, 2017-09, Vol.61 (9)

2017

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Pharmacokinetics of an elevated dosage of micafungin in premature neonates

The Pediatric infectious disease journal, 2009-05, Vol.28 (5), p.412-415

2009

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In vitro combination therapy with isavuconazole against Candida spp

Medical mycology (Oxford), 2017-11, Vol.55 (8), p.859-868

2017

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Isavuconazonium sulfate: a new agent for the treatment of invasive aspergillosis and invasive mucormycosis

Expert review of clinical pharmacology, 2016-07, Vol.9 (7), p.887-897

2016

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Antifungal efficacy of isavuconazole and liposomal amphotericin B in a rabbit model of Exserohilum rostratum meningoencephalitis: A preclinical paradigm for management of CNS phaeohyphomycosis

Medical mycology (Oxford), 2021-02, Vol.59 (2), p.189-196

2021

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Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies

Use of Pharmacokinetic-Pharmacodynamic Analyses To Optimize Therapy with the Systemic Antifungal Micafungin for Invasive Candidiasis or Candidemia

Clinical Pharmacodynamic Index Identification for Micafungin in Esophageal Candidiasis: Dosing Strategy Optimization

Exposure-Response Relationships for Isavuconazole in Patients with Invasive Aspergillosis and Other Filamentous Fungi

In Vitro Activity of Isavuconazole against Opportunistic Fungal Pathogens from Two Mycology Reference Laboratories

Pharmacodynamics of Isavuconazole for Invasive Mold Disease: Role of Galactomannan for Real-Time Monitoring of Therapeutic Response

Safety, tolerability and immunogenicity of a novel 24-valent pneumococcal vaccine in toddlers: A phase 1 randomized controlled trial

Isavuconazole Population Pharmacokinetic Analysis Using Nonparametric Estimation in Patients with Invasive Fungal Disease (Results from the VITAL Study)

Efficacy and Associated Drug Exposures of Isavuconazole and Fluconazole in an Experimental Model of Coccidioidomycosis

Safety, Tolerability, and Population Pharmacokinetics of Intravenous and Oral Isavuconazonium Sulfate in Pediatric Patients

Pharmacodynamics of isavuconazole in experimental invasive pulmonary aspergillosis: implications for clinical breakpoints

Population Pharmacokinetic Modeling of VL-2397, a Novel Systemic Antifungal Agent: Analysis of a Single- and Multiple-Ascending-Dose Study in Healthy Subjects

A Phase 3 Study of Micafungin Versus Amphotericin B Deoxycholate in Infants With Invasive Candidiasis

Impact of Mucositis on Absorption and Systemic Drug Exposure of Isavuconazole

Pharmacokinetics and Concentration-Dependent Efficacy of Isavuconazole for Treatment of Experimental Invasive Pulmonary Aspergillosis

Pharmacodynamics of Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis

Outcomes by MIC Values for Patients Treated with Isavuconazole or Voriconazole for Invasive Aspergillosis in the Phase 3 SECURE and VITAL Trials

Prognostic value of galactomannan: current evidence for monitoring response to antifungal therapy in patients with invasive aspergillosis

In vitro combination of isavuconazole with micafungin or amphotericin B deoxycholate against medically important molds

Population pharmacokinetics of micafungin and its metabolites M1 and M5 in children and adolescents

Combination Therapy with Isavuconazole and Micafungin for Treatment of Experimental Invasive Pulmonary Aspergillosis

Pharmacokinetics of an elevated dosage of micafungin in premature neonates

In vitro combination therapy with isavuconazole against Candida spp

Isavuconazonium sulfate: a new agent for the treatment of invasive aspergillosis and invasive mucormycosis

Antifungal efficacy of isavuconazole and liposomal amphotericin B in a rabbit model of Exserohilum rostratum meningoencephalitis: A preclinical paradigm for management of CNS phaeohyphomycosis

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