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Study on Multi-Target Synergistic Treatment of Alzheimer's Disease Based on Metal Chelators

Current drug targets, 2023-01, Vol.24 (2), p.131-150

2023

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A Review on the Natural Components Applied as Lead Compounds for Potential Multi-target Anti-AD Theranostic Agents

Current medicinal chemistry, 2023-01, Vol.30 (40), p.4586-4604

2023

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Carbon monoxide and ethylene complexes of copper and silver supported by a highly fluorinated tris(triazolyl)borate

Dalton transactions : an international journal of inorganic chemistry, 2009-01 (36), p.7529-7536

2009

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A review on α-mangostin as a potential multi-target-directed ligand for Alzheimer's disease

European journal of pharmacology, 2021-04, Vol.897, p.173950, Article 173950

2021

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Emodin derivatives with multi-factor anti-AD activities: AChE inhibitor, anti-oxidant and metal chelator

Journal of molecular structure, 2021-09, Vol.1239, p.130459, Article 130459

2021

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Xanthone derivatives as potential telomeric G-quadruplex stabilizing and cytotoxic agents: Effects of substitution on quadruplex binding affinity and cytotoxicity

Journal of molecular structure, 2022-12, Vol.1270, p.133894, Article 133894

2022

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Design, synthesis and biological evaluation of naringenin carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer’s disease

Bioorganic & medicinal chemistry letters, 2021-10, Vol.49, p.128316-128316, Article 128316

2021

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Design, synthesis and anti-Alzheimer's disease activity study of xanthone derivatives based on multi-target strategy

Bioorganic & medicinal chemistry letters, 2020-02, Vol.30 (4), p.126927-126927, Article 126927

2020

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Diosmetin derivatives as multifunctional anti-AD ligands: Design, synthesis, and biological evaluation

Chemical biology & drug design, 2024-04, Vol.103 (4), p.e14529-e14529

2024

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Carrier-free Chinese herbal small molecules self-assembly with 3D-porous crystal framework as a synergistic anti-AD agent

International journal of pharmaceutics, 2023-01, Vol.630, p.122458, Article 122458

2023

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A multifunctional anti-AD approach: Design, synthesis, X-ray crystal structure, biological evaluation and molecular docking of chrysin derivatives

European journal of medicinal chemistry, 2022-04, Vol.233, p.114216-114216, Article 114216

2022

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A coumarin-based multifunctional chemosensor for Cu2+/Al3+ as an AD theranostic agent: Synthesis, X-ray single crystal analysis and activity study

Analytica chimica acta, 2023-10, Vol.1279, p.341818-341818, Article 341818

2023

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Novel chrysin derivatives as hidden multifunctional agents for anti-Alzheimer's disease: design, synthesis and in vitro evaluation

European journal of pharmaceutical sciences, 2021-11, Vol.166, p.105976-105976, Article 105976

2021

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Synthesis, Structures, and Conformational Characteristics of Calixarene Monoanions and Dianions

Journal of the American Chemical Society, 2003-05, Vol.125 (20), p.6228-6238

2003

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Synthesis, single crystal characterization and anti-AD activities of a novel complex of Cu(II) with in situ formed protonated chrysin derivative ligand

Journal of inorganic biochemistry, 2023-02, Vol.239, p.112086-112086, Article 112086

2023

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Novel coumarin derivatives as multifunctional anti-AD agents: Design, synthesis, X-ray crystal structure and biological evaluation

Journal of molecular structure, 2022-11, Vol.1268, p.133747, Article 133747

2022

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Chemical composition analysis of Qingyan dropping pills using ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry

Rapid communications in mass spectrometry, 2024-08, Vol.38 (16), p.e9833-n/a

2024

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Multifunctional fluorescence sensor as a potential theranostic agent against Alzheimer's disease

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022-02, Vol.267 (Pt 2), p.120587, Article 120587

2022

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A multifunctional metal regulator as the potential theranostic agent: Design, synthesis, anti-AD activities and metallic ion sensing properties

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022-06, Vol.274, p.121110, Article 121110

2022

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Study of multifunctional anti-AD ligands: design, synthesis, X-ray crystal structure and biological evaluation of diosmetin derivatives

Molecular diversity, 2024-06

2024

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Study on the novel usnic acid derivatives: Design, synthesis, X-Ray crystal structure of Cu(II) complex and anti-AD activities

Journal of molecular structure, 2022-09, Vol.1263, p.133018, Article 133018

2022

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Design, Synthesis and Biological Evaluation of Xanthone Derivatives for Possible Treatment of Alzheimer's Disease Based on Multi‐Target Strategy

Chemistry & biodiversity, 2020-10, Vol.17 (10), p.e2000442-n/a

2020

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Emodin derivatives as promising multi-aspect intervention agents for amyloid aggregation: molecular docking/dynamics simulation, bioactivities evaluation, and cytoprotection

Molecular diversity, 2023-09

2023

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Effect of Bis‐Dimethylamine Substitution on DNA Binding Property and Cytotoxic Activity of Polyhydroxyxanthone

Chemistry & biodiversity, 2022-05, Vol.19 (5), p.e202101021-n/a

2022

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Study on the Mixed-Mode HPLC Separation of Shuang-Huang-Lian and Xue‑Bi‑Jing Injections Based on an Ionic Liquid Column

Journal of the Brazilian Chemical Society, 2018-07, Vol.29 (7), p.1455-1463

2018

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Study on Multi-Target Synergistic Treatment of Alzheimer's Disease Based on Metal Chelators

A Review on the Natural Components Applied as Lead Compounds for Potential Multi-target Anti-AD Theranostic Agents

Carbon monoxide and ethylene complexes of copper and silver supported by a highly fluorinated tris(triazolyl)borate

A review on α-mangostin as a potential multi-target-directed ligand for Alzheimer's disease

Emodin derivatives with multi-factor anti-AD activities: AChE inhibitor, anti-oxidant and metal chelator

Xanthone derivatives as potential telomeric G-quadruplex stabilizing and cytotoxic agents: Effects of substitution on quadruplex binding affinity and cytotoxicity

Design, synthesis and biological evaluation of naringenin carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer’s disease

Design, synthesis and anti-Alzheimer's disease activity study of xanthone derivatives based on multi-target strategy

Diosmetin derivatives as multifunctional anti-AD ligands: Design, synthesis, and biological evaluation

Carrier-free Chinese herbal small molecules self-assembly with 3D-porous crystal framework as a synergistic anti-AD agent

A multifunctional anti-AD approach: Design, synthesis, X-ray crystal structure, biological evaluation and molecular docking of chrysin derivatives

A coumarin-based multifunctional chemosensor for Cu2+/Al3+ as an AD theranostic agent: Synthesis, X-ray single crystal analysis and activity study

Novel chrysin derivatives as hidden multifunctional agents for anti-Alzheimer's disease: design, synthesis and in vitro evaluation

Synthesis, Structures, and Conformational Characteristics of Calixarene Monoanions and Dianions

Synthesis, single crystal characterization and anti-AD activities of a novel complex of Cu(II) with in situ formed protonated chrysin derivative ligand

Novel coumarin derivatives as multifunctional anti-AD agents: Design, synthesis, X-ray crystal structure and biological evaluation

Chemical composition analysis of Qingyan dropping pills using ultra‐high‐performance liquid chromatography‐quadrupole time‐of‐flight mass spectrometry

Multifunctional fluorescence sensor as a potential theranostic agent against Alzheimer's disease

A multifunctional metal regulator as the potential theranostic agent: Design, synthesis, anti-AD activities and metallic ion sensing properties

Study of multifunctional anti-AD ligands: design, synthesis, X-ray crystal structure and biological evaluation of diosmetin derivatives

Study on the novel usnic acid derivatives: Design, synthesis, X-Ray crystal structure of Cu(II) complex and anti-AD activities

Design, Synthesis and Biological Evaluation of Xanthone Derivatives for Possible Treatment of Alzheimer's Disease Based on Multi‐Target Strategy

Emodin derivatives as promising multi-aspect intervention agents for amyloid aggregation: molecular docking/dynamics simulation, bioactivities evaluation, and cytoprotection

Effect of Bis‐Dimethylamine Substitution on DNA Binding Property and Cytotoxic Activity of Polyhydroxyxanthone

Study on the Mixed-Mode HPLC Separation of Shuang-Huang-Lian and Xue‑Bi‑Jing Injections Based on an Ionic Liquid Column

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