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Development of Novel Potent Orally Bioavailable Oseltamivir Derivatives Active against Resistant Influenza A

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.759-769

2014

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Discovery of N‑(4-Aminobutyl)‑N′‑(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase‑1 (hDDAH-1)

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.425-432

2020

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Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability

Journal of pharmaceutical sciences, 2015-09, Vol.104 (9), p.3208-3219

2015

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Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC)

Biochemical journal, 2011-01, Vol.433 (2), p.383-391

2011

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Reduction of N ω-hydroxy- L -arginine by the mitochondrial amidoxime reducing component (mARC)

Biochemical journal, 2011-01, Vol.433 (2), p.383-391

2011

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Modulating the NO generating system from a medicinal chemistry perspective: current trends and therapeutic options in cardiovascular disease

Pharmacology & therapeutics (Oxford), 2010-06, Vol.126 (3), p.279-300

2010

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Prodrug design for the potent cardiovascular agent Nω-hydroxy-L-arginine (NOHA): synthetic approaches and physicochemical characterization

Organic & biomolecular chemistry, 2011-07, Vol.9 (14), p.5249-5259

2011

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Structure–activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: Alkenyl-amidines as new leads

Bioorganic & medicinal chemistry, 2008-12, Vol.16 (24), p.10205-10209

2008

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Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine

Journal of organic chemistry, 2008-02, Vol.73 (3), p.1025-1030

2008

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Synthesis and biological evaluation of l-valine-amidoximeesters as double prodrugs of amidines

Bioorganic & medicinal chemistry, 2011-03, Vol.19 (6), p.1907-1914

2011

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Synthetic Approaches to N δ-Methylated l-Arginine, N ω-Hydroxy-l-arginine, l-Citrulline, and N δ-Cyano-l-ornithine

Journal of organic chemistry, 2008-02, Vol.73 (3), p.1025-1030

2008

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New Prodrugs of the Antiprotozoal Drug Pentamidine

ChemMedChem, 2011-12, Vol.6 (12), p.2233-2242

2011

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Efficient Synthesis of Optically Pure Nω-Alkylated l-Arginines

Synthesis (Stuttgart), 2008-08, Vol.2008 (15), p.2391-2397

2008

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N δ-Methylated l-arginine derivatives and their effects on the nitric oxide generating system

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (5), p.2305-2312

2008

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The Peptidylglycine α‐Amidating Monooxygenase (PAM): A Novel Prodrug Strategy for Amidoximes and N‐Hydroxyguanidines?

ChemMedChem, 2009-10, Vol.4 (10), p.1595-1599

2009

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N(delta)-Methylated L-arginine derivatives and their effects on the nitric oxide generating system

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (5), p.2305-2312

2008

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Synthetic Approaches to Nδ-Methylated L-Arginine, Aω-Hydroxy-L-arginine, L-Citrulline, and Nδ-Cyano-L-ornithine

Journal of organic chemistry, 2008, Vol.73 (3), p.1025-1030

2008

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Arylazoamidoximes and Related Compounds as NO-modulators

Archiv der Pharmazie (Weinheim), 2010-01, Vol.343 (1), p.9-16

2010

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Development of Novel Potent Orally Bioavailable Oseltamivir Derivatives Active against Resistant Influenza A

Discovery of N‑(4-Aminobutyl)‑N′‑(2-methoxyethyl)guanidine as the First Selective, Nonamino Acid, Catalytic Site Inhibitor of Human Dimethylarginine Dimethylaminohydrolase‑1 (hDDAH-1)

Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability

Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC)

Reduction of N ω-hydroxy- L -arginine by the mitochondrial amidoxime reducing component (mARC)

Modulating the NO generating system from a medicinal chemistry perspective: current trends and therapeutic options in cardiovascular disease

Prodrug design for the potent cardiovascular agent Nω-hydroxy-L-arginine (NOHA): synthetic approaches and physicochemical characterization

Structure–activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: Alkenyl-amidines as new leads

Synthetic approaches to N(delta)-methylated L-arginine, N(omega)-hydroxy-L-arginine, L-citrulline, and N(delta)-cyano-L-ornithine

Synthesis and biological evaluation of l-valine-amidoximeesters as double prodrugs of amidines

Synthetic Approaches to N δ-Methylated l-Arginine, N ω-Hydroxy-l-arginine, l-Citrulline, and N δ-Cyano-l-ornithine

New Prodrugs of the Antiprotozoal Drug Pentamidine

Efficient Synthesis of Optically Pure Nω-Alkylated l-Arginines

N δ-Methylated l-arginine derivatives and their effects on the nitric oxide generating system

The Peptidylglycine α‐Amidating Monooxygenase (PAM): A Novel Prodrug Strategy for Amidoximes and N‐Hydroxyguanidines?

N(delta)-Methylated L-arginine derivatives and their effects on the nitric oxide generating system

Synthetic Approaches to Nδ-Methylated L-Arginine, Aω-Hydroxy-L-arginine, L-Citrulline, and Nδ-Cyano-L-ornithine

Arylazoamidoximes and Related Compounds as NO-modulators

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