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Impact of symptoms by gender and age in Japanese subjects with irritable bowel syndrome with constipation (IBS-C): a large population-based internet survey

BioPsychoSocial medicine, 2018-09, Vol.12 (1), p.12-12, Article 12

2018

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Influence of the requirement for abdominal pain in the diagnosis of irritable bowel syndrome with constipation (IBS-C) under the Rome IV criteria using data from a large Japanese population-based internet survey

BioPsychoSocial medicine, 2018-12, Vol.12 (1), p.18-18, Article 18

2018

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Risk-Based Monitoring Approach to Ensure the Quality of Clinical Study Data and Enable Effective Monitoring

Therapeutic innovation & regulatory science, 2020, Vol.54 (1), p.139-143

2020

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Pharmacological and clinical profile of linaclotide (Linzess®), a novel therapeutic agent for irritable bowel syndrome with constipation and chronic constipation

Nihon yakurigaku zasshi, 2019, Vol.153 (6), p.289-298

2019

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Pharmacological and clinical profile of linaclotide (Linzess®), a novel therapeutic agent for irritable bowel syndrome with constipation and chronic constipation

Folia Pharmacologica Japonica, 2019, Vol.153(6), pp.289-298

2019

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High‐dose linaclotide is effective and safe in patients with chronic constipation: A phase III randomized, double‐blind, placebo‐controlled study with a long‐term open‐label extension study in Japan

Neurogastroenterology and motility, 2019-01, Vol.31 (1), p.e13487-n/a

2019

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A randomized controlled and long‐term linaclotide study of irritable bowel syndrome with constipation patients in Japan

Neurogastroenterology and motility, 2018-12, Vol.30 (12), p.e13444-n/a

2018

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Abdominal bloating is the most bothersome symptom in irritable bowel syndrome with constipation (IBS-C): a large population-based Internet survey in Japan

BioPsychoSocial medicine, 2016-06, Vol.10 (1), p.19-19, Article 19

2016

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Dose‐finding study of linaclotide in Japanese patients with chronic constipation: A phase II randomized, double‐blind, and placebo‐controlled study

Neurogastroenterology and motility, 2018-12, Vol.30 (12), p.e13442-n/a

2018

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Mo1627 Abdominal Bloating Is the Most Bothersome Symptom in Irritable Bowel Syndrome With Constipation (IBS-C): A Large Population-Based Internet Survey in Japan

Gastroenterology (New York, N.Y. 1943), 2016-04, Vol.150 (4), p.S735-S735

2016

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Tu1627 - Linaclotide is Effective and Safe for Patients with Chronic Constipation in Japan: A Phase III Randomized, Double-Blind, Placebo-Controlled Study with a Long-Term Open-Label Extension Study

Gastroenterology (New York, N.Y. 1943), 2018-05, Vol.154 (6), p.S-973-S-974

2018

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Risk-Based Monitoring Approach to Ensure the Quality of Clinical Study Data and Enable Effective Monitoring

Therapeutic innovation & regulatory science, 2019-01, p.216847901881946

2019

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Mo1626 Determining an Optimal Dose of Linaclotide in Use in Japanese Patients With Irritable Bowel Syndrome With Constipation: A Phase II Randomized, Double-Blind, Placebo-Controlled Study

Gastroenterology (New York, N.Y. 1943), 2016-04, Vol.150 (4), p.S735-S735

2016

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Neurogastroenterology and motility, 2019-01, Vol.31 (1)

2019

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Su1543 - Dose-Finding of Linaclotide for Patients with Chronic Constipation in Japan: A Phase II Randomized, Double-Blind, and Placebo-Controlled Study

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S515-S516

2017

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Dose-Finding of Linaclotide for Patients with Chronic Constipation in Japan: A Phase II Randomized, Double-Blind, and Placebo-Controlled Study

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S515-S516

2017

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Mo1548 - Linaclotide is Effective and Safe for Patients with Irritable Bowel Syndrome with Constipation in Japan: A Phase III Randomized, Double-Blind, and Placebo-Controlled and Long-Term Extension Study

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S714-S714

2017

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Linaclotide is Effective and Safe for Patients with Irritable Bowel Syndrome with Constipation in Japan: A Phase III Randomized, Double-Blind, and Placebo-Controlled and Long-Term Extension Study

Gastroenterology (New York, N.Y. 1943), 2017-04, Vol.152 (5), p.S714-S714

2017

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Risk-Based Monitoring Approach to Ensure the Quality of Clinical Study Data and Enable Effective Monitoring

Therapeutic innovation & regulatory science, 2019-01, p.2168479018819464

2019

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便秘型過敏性腸症候群及び慢性便秘症に対する新規作用機序を有する治療薬　リナクロチド（リンゼス®錠0.25 mg）の薬理学的特徴並びに臨床試験成績

日本薬理学雑誌, 2019, Vol.153(6), pp.289-298

2019

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Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery

The Journal of cell biology, 2020-10, Vol.219 (10)

2020

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Proteomics-based comparison of transporter expression profiles in BeWo and JEG-3 cells

Placenta (Eastbourne), 2023-09, Vol.140, p.e81-e82

2023

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The TrkC-PTPσ complex governs synapse maturation and anxiogenic avoidance via synaptic protein phosphorylation

The EMBO journal, 2024-09

2024

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Flexibacter japonensis sp. nov., a New Species That Produces a Novel Inhibitor of Human Leukocyte Elastase Isolated from Soil

Current microbiology, 1996-08, Vol.33 (2), p.89-93, Article 89

1996

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Impact of symptoms by gender and age in Japanese subjects with irritable bowel syndrome with constipation (IBS-C): a large population-based internet survey

Influence of the requirement for abdominal pain in the diagnosis of irritable bowel syndrome with constipation (IBS-C) under the Rome IV criteria using data from a large Japanese population-based internet survey

Risk-Based Monitoring Approach to Ensure the Quality of Clinical Study Data and Enable Effective Monitoring

Pharmacological and clinical profile of linaclotide (Linzess®), a novel therapeutic agent for irritable bowel syndrome with constipation and chronic constipation

Pharmacological and clinical profile of linaclotide (Linzess®), a novel therapeutic agent for irritable bowel syndrome with constipation and chronic constipation

High‐dose linaclotide is effective and safe in patients with chronic constipation: A phase III randomized, double‐blind, placebo‐controlled study with a long‐term open‐label extension study in Japan

A randomized controlled and long‐term linaclotide study of irritable bowel syndrome with constipation patients in Japan

Phase 3 study of gilteritinib versus salvage chemotherapy in predominantly Asian patients with relapsed/refractory FLT3-mutated acute myeloid leukemia

Abdominal bloating is the most bothersome symptom in irritable bowel syndrome with constipation (IBS-C): a large population-based Internet survey in Japan

Dose‐finding study of linaclotide in Japanese patients with chronic constipation: A phase II randomized, double‐blind, and placebo‐controlled study

Mo1627 Abdominal Bloating Is the Most Bothersome Symptom in Irritable Bowel Syndrome With Constipation (IBS-C): A Large Population-Based Internet Survey in Japan

Tu1627 - Linaclotide is Effective and Safe for Patients with Chronic Constipation in Japan: A Phase III Randomized, Double-Blind, Placebo-Controlled Study with a Long-Term Open-Label Extension Study

Risk-Based Monitoring Approach to Ensure the Quality of Clinical Study Data and Enable Effective Monitoring

Mo1626 Determining an Optimal Dose of Linaclotide in Use in Japanese Patients With Irritable Bowel Syndrome With Constipation: A Phase II Randomized, Double-Blind, Placebo-Controlled Study

Cover Image

Su1543 - Dose-Finding of Linaclotide for Patients with Chronic Constipation in Japan: A Phase II Randomized, Double-Blind, and Placebo-Controlled Study

Dose-Finding of Linaclotide for Patients with Chronic Constipation in Japan: A Phase II Randomized, Double-Blind, and Placebo-Controlled Study

Mo1548 - Linaclotide is Effective and Safe for Patients with Irritable Bowel Syndrome with Constipation in Japan: A Phase III Randomized, Double-Blind, and Placebo-Controlled and Long-Term Extension Study

Linaclotide is Effective and Safe for Patients with Irritable Bowel Syndrome with Constipation in Japan: A Phase III Randomized, Double-Blind, and Placebo-Controlled and Long-Term Extension Study

Risk-Based Monitoring Approach to Ensure the Quality of Clinical Study Data and Enable Effective Monitoring

便秘型過敏性腸症候群及び慢性便秘症に対する新規作用機序を有する治療薬　リナクロチド（リンゼス®錠0.25 mg）の薬理学的特徴並びに臨床試験成績

Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery

Proteomics-based comparison of transporter expression profiles in BeWo and JEG-3 cells

The TrkC-PTPσ complex governs synapse maturation and anxiogenic avoidance via synaptic protein phosphorylation

Flexibacter japonensis sp. nov., a New Species That Produces a Novel Inhibitor of Human Leukocyte Elastase Isolated from Soil

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