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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.126-141

2013

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ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.64-79

2013

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The case of subcutaneous emphysema in a Eurasian reed warbler nestling

European zoological journal, 2023-12, Vol.90 (2), p.673-676

2023

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Evaluation of Atypical Cytochrome P450 Kinetics with Two-Substrate Models: Evidence That Multiple Substrates Can Simultaneously Bind to Cytochrome P450 Active Sites

Biochemistry (Easton), 1998-03, Vol.37 (12), p.4137-4147

1998

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Silver Nanoforms as a Therapeutic Agent for Killing Escherichia coli and Certain ESKAPE Pathogens

Current microbiology, 2016-07, Vol.73 (1), p.139-147

2016

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Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil

British journal of clinical pharmacology, 1999-05, Vol.47 (5), p.545-552

1999

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Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site

Biochemistry (Easton), 1994-05, Vol.33 (21), p.6450-6455

1994

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Spin dynamics in p -doped semiconductor nanostructures subject to a magnetic field tilted from the Voigt geometry

Physical review. B, Condensed matter and materials physics, 2013-10, Vol.88 (15), Article 155303

2013

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Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Chemical research in toxicology, 1992-01, Vol.5 (1), p.54-59

1992

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Selective biotransformation of taxol to 6α-hydroxytaxol by human cytochrome P450 2C8

Cancer research (Chicago, Ill.), 1994-11, Vol.54 (21), p.5543-5546

1994

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Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone

Carcinogenesis (New York), 1997, Vol.18 (1), p.207-214

1997

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profiles of enterotoxin genes in Staphylococcus aureus from nasal carriers

Letters in applied microbiology, 2006-04, Vol.42 (4), p.315-320

2006

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Intracellular Unbound Atorvastatin Concentrations in the Presence of Metabolism and Transport

The Journal of pharmacology and experimental therapeutics, 2016-10, Vol.359 (1), p.26-36

2016

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Influence of microflora composition on safety and colour parameters of "kumpia wieprzowa" during ripening

Polish journal of veterinary sciences, 2013-01, Vol.16 (2), p.299-305

2013

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Selection and electrophoretic characterization of Salmonella enterica subsp. enterica biocide variants resistant to antibiotics

Polish Journal of Veterinary Sciences, 2015-01, Vol.18 (4), p.725-732

2015

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A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4

The Journal of biological chemistry, 2001-01, Vol.276 (3), p.2256-2262

2001

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Mechanism of Oxidative Amine Dealkylation of Substituted N,N-Dimethylanilines by Cytochrome P-450: Application of Isotope Effect Profiles

Journal of the American Chemical Society, 1995-04, Vol.117 (13), p.3657-3664

1995

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O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4

Molecular pharmacology, 1994-02, Vol.45 (2), p.352-358

1994

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A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding

Biopharmaceutics & drug disposition, 2016-04, Vol.37 (3), p.123-141

2016

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THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS

Drug metabolism reviews, 2000-01, Vol.32 (3-4), p.339-361

2000

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Computational models for cytochrome P450: a predictive electronic model for aromatic oxidation and hydrogen atom abstraction

Drug metabolism and disposition, 2002-01, Vol.30 (1), p.7-12

2002

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Consequences Of Long-Term Bacteria's Exposure To Silver Nanoformulations With Different PhysicoChemical Properties

International journal of nanomedicine, 2020-01, Vol.15, p.199-213

2020

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Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation

European journal of clinical pharmacology, 1997-06, Vol.52 (4), p.293-298

1997

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Human CYP2C9 and CYP2A6 mediate formation of the hepatotoxin 4-ene-valproic acid

The Journal of pharmacology and experimental therapeutics, 1997-11, Vol.283 (2), p.698

1997

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Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

European journal of pharmacology, 2000-04, Vol.394 (2), p.199-209

2000

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Intracellular Drug Concentrations and Transporters: Measurement, Modeling, and Implications for the Liver

ITC Recommendations for Transporter Kinetic Parameter Estimation and Translational Modeling of Transport-Mediated PK and DDIs in Humans

The case of subcutaneous emphysema in a Eurasian reed warbler nestling

Evaluation of Atypical Cytochrome P450 Kinetics with Two-Substrate Models: Evidence That Multiple Substrates Can Simultaneously Bind to Cytochrome P450 Active Sites

Silver Nanoforms as a Therapeutic Agent for Killing Escherichia coli and Certain ESKAPE Pathogens

Cytochrome P450 isoforms involved in metabolism of the enantiomers of verapamil and norverapamil

Activation of CYP3A4: Evidence for the Simultaneous Binding of Two Substrates in a Cytochrome P450 Active Site

Spin dynamics in p -doped semiconductor nanostructures subject to a magnetic field tilted from the Voigt geometry

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

Selective biotransformation of taxol to 6α-hydroxytaxol by human cytochrome P450 2C8

Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone

profiles of enterotoxin genes in Staphylococcus aureus from nasal carriers

Intracellular Unbound Atorvastatin Concentrations in the Presence of Metabolism and Transport

Influence of microflora composition on safety and colour parameters of "kumpia wieprzowa" during ripening

Selection and electrophoretic characterization of Salmonella enterica subsp. enterica biocide variants resistant to antibiotics

A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4

Mechanism of Oxidative Amine Dealkylation of Substituted N,N-Dimethylanilines by Cytochrome P-450: Application of Isotope Effect Profiles

O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4

A physiologically based pharmacokinetic model to predict the pharmacokinetics of highly protein-bound drugs and the impact of errors in plasma protein binding

THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS

Computational models for cytochrome P450: a predictive electronic model for aromatic oxidation and hydrogen atom abstraction

Consequences Of Long-Term Bacteria's Exposure To Silver Nanoformulations With Different PhysicoChemical Properties

Involvement of multiple cytochrome P450 isoforms in naproxen O-demethylation

Human CYP2C9 and CYP2A6 mediate formation of the hepatotoxin 4-ene-valproic acid

Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism

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