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Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity

Toxicological sciences, 2018-04, Vol.162 (2), p.570-581

2018

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Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases

Toxicological sciences, 2019-04, Vol.168 (2), p.430-442

2019

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Progress towards Development of an Amphibian-Based Thyroid Screening Assay Using Xenopus laevis. Organismal and Thyroidal Responses to the Model Compounds 6-Propylthiouracil, Methimazole, and Thyroxine

Toxicological sciences, 2005-10, Vol.87 (2), p.353-364

2005

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Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis

Aquatic toxicology, 2010-06, Vol.98 (1), p.44-50

2010

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Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an aromatase inhibitor

Aquatic toxicology, 2009-01, Vol.91 (2), p.143-150

2009

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Metamorphic inhibition of Xenopus laevis by sodium perchlorate: Effects on development and thyroid histology

Environmental toxicology and chemistry, 2005-04, Vol.24 (4), p.926-933

2005

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Characterization of thyroid hormone transporter expression during tissue-specific metamorphic events in Xenopus tropicalis

General and comparative endocrinology, 2010-08, Vol.168 (1), p.149-159

2010

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In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles

Toxicological sciences, 2015-08, Vol.146 (2), p.254-264

2015

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Thyroid-stimulating hormone (TSH): Measurement of intracellular, secreted, and circulating hormone in Xenopus laevis and Xenopus tropicalis

General and comparative endocrinology, 2011-05, Vol.171 (3), p.319-325

2011

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Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase

Aquatic toxicology, 2022-08, Vol.249, p.106227-106227, Article 106227

2022

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Reproductive maturation of the tropical clawed frog: Xenopus tropicalis

General and comparative endocrinology, 2009-01, Vol.160 (2), p.117-123

2009

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Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development in Xenopus laevis Using Iopanoic Acid

Toxicological sciences, 2022-04, Vol.187 (1), p.139-149

2022

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Targeted Pathway-based In Vivo Testing Using Thyroperoxidase Inhibition to Evaluate Plasma Thyroxine as a Surrogate Metric of Metamorphic Success in Model Amphibian Xenopus laevis

Toxicological sciences, 2020-06, Vol.175 (2), p.236-250

2020

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In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase

Toxicology in vitro, 2021-03, Vol.71, p.105073-105073, Article 105073

2021

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Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals

Toxicology in vitro, 2021-06, Vol.73, p.105141-105141, Article 105141

2021

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Evaluating Iodide Recycling Inhibition as a Novel Molecular Initiating Event for Thyroid Axis Disruption in Amphibians

Toxicological sciences, 2018-12, Vol.166 (2), p.318-331

2018

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Effects of multiple life stage exposure to the fungicide prochloraz in Xenopus laevis: Manifestations of antiandrogenic and other modes of toxicity

Aquatic toxicology, 2018-06, Vol.199, p.240-251

2018

Volltextzugriff (PDF)

Development of the Larval Amphibian Growth and Development Assay: effects of chronic 4-tert-octylphenol or 17β-trenbolone exposure in Xenopus laevis from embryo to juvenile

Journal of applied toxicology, 2016-12, Vol.36 (12), p.1639-1650

2016

Volltextzugriff (PDF)

Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas)

Environmental toxicology and chemistry, 2001-06, Vol.20 (6), p.1276-1290

2001

Volltextzugriff (PDF)

Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole

Aquatic toxicology, 2013-01, Vol.126 (15), p.128-136

2013

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Evaluation of the Aromatase Inhibitor Fadrozole in a Short-Term Reproduction Assay with the Fathead Minnow (Pimephales promelas)

Toxicological sciences, 2002-05, Vol.67 (1), p.121-130

2002

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Effects of the androgenic growth promoter 17-β-trenbolone on fecundity and reproductive endocrinology of the fathead minnow

Environmental toxicology and chemistry, 2003-06, Vol.22 (6), p.1350-1360

2003

Volltextzugriff (PDF)

Development of the Larval Amphibian Growth and Development Assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile

Journal of applied toxicology, 2016-12, Vol.36 (12), p.1651-1661

2016

Volltextzugriff (PDF)

Trenbolone causes mortality and altered sexual differentiation in Xenopus tropicalis during larval development

Environmental toxicology and chemistry, 2012-10, Vol.31 (10), p.2391-2398

2012

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Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow

Aquatic toxicology, 2004-11, Vol.70 (2), p.99-110

2004

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Screening the ToxCast Phase 1 Chemical Library for Inhibition of Deiodinase Type 1 Activity

Screening the ToxCast Phase 1, Phase 2, and e1k Chemical Libraries for Inhibitors of Iodothyronine Deiodinases

Progress towards Development of an Amphibian-Based Thyroid Screening Assay Using Xenopus laevis. Organismal and Thyroidal Responses to the Model Compounds 6-Propylthiouracil, Methimazole, and Thyroxine

Early temporal effects of three thyroid hormone synthesis inhibitors in Xenopus laevis

Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an aromatase inhibitor

Metamorphic inhibition of Xenopus laevis by sodium perchlorate: Effects on development and thyroid histology

Characterization of thyroid hormone transporter expression during tissue-specific metamorphic events in Xenopus tropicalis

In Vitro, Ex Vivo, and In Vivo Determination of Thyroid Hormone Modulating Activity of Benzothiazoles

Thyroid-stimulating hormone (TSH): Measurement of intracellular, secreted, and circulating hormone in Xenopus laevis and Xenopus tropicalis

Cross-species comparison of chemical inhibition of human and Xenopus iodotyrosine deiodinase

Reproductive maturation of the tropical clawed frog: Xenopus tropicalis

Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development in Xenopus laevis Using Iopanoic Acid

Targeted Pathway-based In Vivo Testing Using Thyroperoxidase Inhibition to Evaluate Plasma Thyroxine as a Surrogate Metric of Metamorphic Success in Model Amphibian Xenopus laevis

In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase

Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals

Evaluating Iodide Recycling Inhibition as a Novel Molecular Initiating Event for Thyroid Axis Disruption in Amphibians

Effects of multiple life stage exposure to the fungicide prochloraz in Xenopus laevis: Manifestations of antiandrogenic and other modes of toxicity

Development of the Larval Amphibian Growth and Development Assay: effects of chronic 4-tert-octylphenol or 17β-trenbolone exposure in Xenopus laevis from embryo to juvenile

Description and evaluation of a short-term reproduction test with the fathead minnow (Pimephales promelas)

Inhibition of the thyroid hormone pathway in Xenopus laevis by 2-mercaptobenzothiazole

Evaluation of the Aromatase Inhibitor Fadrozole in a Short-Term Reproduction Assay with the Fathead Minnow (Pimephales promelas)

Effects of the androgenic growth promoter 17-β-trenbolone on fecundity and reproductive endocrinology of the fathead minnow

Development of the Larval Amphibian Growth and Development Assay: Effects of benzophenone-2 exposure in Xenopus laevis from embryo to juvenile

Trenbolone causes mortality and altered sexual differentiation in Xenopus tropicalis during larval development

Characterization of responses to the antiandrogen flutamide in a short-term reproduction assay with the fathead minnow

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