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The emerging role of miR-200 family of MicroRNAs in epithelial-mesenchymal transition and cancer metastasis

RNA biology, 2008-07, Vol.5 (3), p.115-119

2008

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The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2

The Journal of biological chemistry, 2008-05, Vol.283 (22), p.14910-14914

2008

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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

Nature medicine, 2011-09, Vol.17 (9), p.1101-1108

2011

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An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide)

Cancer discovery, 2013-09, Vol.3 (9), p.1030-1043

2013

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Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

Nature communications, 2017-05, Vol.8 (1), p.15522-15522, Article 15522

2017

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Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

Nature communications, 2017-07, Vol.8 (1), p.103-14, Article 103

2017

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MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells

Journal of translational medicine, 2011-03, Vol.9 (1), p.30-30, Article 30

2011

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Author Correction: Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

Nature communications, 2019-06, Vol.10 (1), p.2527-2527, Article 2527

2019

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Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis

Blood, 2006-05, Vol.107 (10), p.3868-3875

2006

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Targeting the transforming growth factor-β signalling pathway in metastatic cancer

European journal of cancer (1990), 2010-05, Vol.46 (7), p.1232-1240

2010

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RanBP10 Is a Cytoplasmic Guanine Nucleotide Exchange Factor That Modulates Noncentrosomal Microtubules

The Journal of biological chemistry, 2008-05, Vol.283 (20), p.14109-14119

2008

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Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis

Nature medicine, 2009-08, Vol.15 (8), p.960-966

2009

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Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (8), p.1740-1745

2019

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Interactions between the megakaryocyte/platelet-specific β1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions

Blood, 2004-12, Vol.104 (13), p.3949-3957

2004

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Identification of 2‑Sulfonyl/Sulfonamide Pyrimidines as Covalent Inhibitors of WRN Using a Multiplexed High-Throughput Screening Assay

Biochemistry (Easton), 2023-07, Vol.62 (14), p.2147-2160

2023

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Generating a Murine PTEN Null Cell Line to Discover the Key Role of p110β-PAK1 in Castration-Resistant Prostate Cancer Invasion

Molecular cancer research, 2023-12, Vol.21 (12), p.1317-1328

2023

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Abstract 498: Integrating bulk and spatial profiling technologies for the discovery of RNA and protein biomarkers in muscle invasive bladder cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.498-498

2019

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Abstract P1-17-03: H3B-6545 in combination with palbociclib in women with metastatic estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 (HER2)-negative breast cancer, phase 1b study

Cancer research (Chicago, Ill.), 2022-02, Vol.82 (4_Supplement), p.P1-P1-17-03

2022

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Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA)

Cancer chemotherapy and pharmacology, 2019-01, Vol.83 (1), p.151-160

2019

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Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT)

The Journal of biological chemistry, 2012-12, Vol.287 (50), p.42180-42194

2012

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Modulation of immunosurveillance by tumor-intrinsic genomic alterations

Immunotherapy, 2017-12, Vol.9 (16), p.1305-1307

2017

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Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists

The Journal of biological chemistry, 2022-11, Vol.298 (11), p.102539, Article 102539

2022

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Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer

Molecular cancer research, 2022-05, Vol.20 (5), p.673-685

2022

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Targeting the transforming growth factor-β signalling pathway in metastatic cancer: Stopping Cancer in its Tracks: Metastasis as a Therapeutic Target

European journal of cancer (1990), 2010, Vol.46 (7), p.1232-1240

2010

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H3B-6545, a selective estrogen receptor covalent antagonist, prevents bone loss in ovariectomized Sprague-Dawley rats

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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The emerging role of miR-200 family of MicroRNAs in epithelial-mesenchymal transition and cancer metastasis

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide)

Splicing modulators act at the branch point adenosine binding pocket defined by the PHF5A–SF3b complex

Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells

Author Correction: Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer

Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis

Targeting the transforming growth factor-β signalling pathway in metastatic cancer

RanBP10 Is a Cytoplasmic Guanine Nucleotide Exchange Factor That Modulates Noncentrosomal Microtubules

Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis

Estrogen Receptor Covalent Antagonists: The Best Is Yet to Come

Interactions between the megakaryocyte/platelet-specific β1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions

Identification of 2‑Sulfonyl/Sulfonamide Pyrimidines as Covalent Inhibitors of WRN Using a Multiplexed High-Throughput Screening Assay

Generating a Murine PTEN Null Cell Line to Discover the Key Role of p110β-PAK1 in Castration-Resistant Prostate Cancer Invasion

Abstract 498: Integrating bulk and spatial profiling technologies for the discovery of RNA and protein biomarkers in muscle invasive bladder cancer

Abstract P1-17-03: H3B-6545 in combination with palbociclib in women with metastatic estrogen receptor-positive (ER+), human epidermal growth factor receptor 2 (HER2)-negative breast cancer, phase 1b study

Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERα covalent antagonist (SERCA)

Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT)

Modulation of immunosurveillance by tumor-intrinsic genomic alterations

Biochemical and structural basis for the pharmacological inhibition of nuclear hormone receptor PPARγ by inverse agonists

Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer

Targeting the transforming growth factor-β signalling pathway in metastatic cancer: Stopping Cancer in its Tracks: Metastasis as a Therapeutic Target

H3B-6545, a selective estrogen receptor covalent antagonist, prevents bone loss in ovariectomized Sprague-Dawley rats

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