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GABA signalling in human pancreatic islets

Frontiers in endocrinology (Lausanne), 2023, Vol.14, p.1059110-1059110

2023

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The GLP-1 Receptor Agonist Exendin-4 and Diazepam Differentially Regulate GABAA Receptor-Mediated Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons

PloS one, 2015-04, Vol.10 (4), p.e0124765-e0124765

2015

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GABAA Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets

International journal of molecular sciences, 2020-01, Vol.21 (2), p.600

2020

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GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes

EBioMedicine, 2018-04, Vol.30, p.283-294

2018

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Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetes

PloS one, 2018-12, Vol.13 (12), p.e0208981-e0208981

2018

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Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic β Cells

EBioMedicine, 2018-04, Vol.30, p.273-282

2018

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ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function

Frontiers in molecular neuroscience, 2022-10, Vol.15, p.988993-988993

2022

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Interferon-γ potentiates GABAA receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons

Journal of neuroimmunology, 2019-12, Vol.337, p.577050-577050, Article 577050

2019

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GLP-1 and exendin-4 transiently enhance GABAA receptor-mediated synaptic and tonic currents in rat hippocampal CA3 pyramidal neurons

Diabetes (New York, N.Y.), 2015-01, Vol.64 (1), p.79-89

2015

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Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

BMC pharmacology & toxicology, 2017-12, Vol.18 (1), p.83-83, Article 83

2017

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Tonic GABA‐activated synaptic and extrasynaptic currents in dentate gyrus granule cells and CA3 pyramidal neurons along the mouse hippocampal dorsoventral axis

Hippocampus, 2020-11, Vol.30 (11), p.1146-1157

2020

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Insulin enhances GABAA receptor-mediated inhibitory currents in rat central amygdala neurons

Neuroscience letters, 2018-04, Vol.671, p.76-81

2018

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Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality

Experimental cell research, 2019-10, Vol.383 (1), p.111469-111469, Article 111469

2019

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Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers

International journal of molecular sciences, 2019-12, Vol.20 (24), p.6172

2019

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Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa

Journal of medicinal chemistry, 2023-01, Vol.66 (2), p.1380-1425

2023

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Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age‐dependent manner, normalizes GABA‐activated currents in the tg‐APPSwe mouse model of Alzheimer’s disease

Acta Physiologica, 2021-06, Vol.232 (2), p.e13623-n/a

2021

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New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus

Journal of medicinal chemistry, 2023-03, Vol.66 (6), p.3968-3994

2023

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Insulin enhances GABA A receptor-mediated inhibitory currents in rat central amygdala neurons

Neuroscience letters, 2018-04, Vol.671, p.76

2018

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In Intact Islets Interstitial GABA Activates GABAA Receptors That Generate Tonic Currents in α-Cells

PloS one, 2013-06, Vol.8 (6), p.e67228

2013

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AMPA, NMDA and kainate glutamate receptor subunits are expressed in human peripheral blood mononuclear cells (PBMCs) where the expression of GluK4 is altered by pregnancy and GluN2D by depression in pregnant women

Journal of neuroimmunology, 2017-04, Vol.305, p.51-58

2017

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Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma

European journal of pharmacology, 2015-02, Vol.748, p.101-107

2015

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Normal human CD4+ helper T cells express Kv1.1 voltage-gated K+ channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway

Journal of Neural Transmission, 2016-03, Vol.123 (3), p.137-157

2016

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In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells

PloS one, 2013, Vol.8 (6), p.e67228

2013

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GABA A Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets

International journal of molecular sciences, 2020-01, Vol.21 (2)

2020

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Interferon-γ potentiates GABA A receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons

Journal of neuroimmunology, 2019-09, Vol.337, p.577050

2019

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GABA signalling in human pancreatic islets

The GLP-1 Receptor Agonist Exendin-4 and Diazepam Differentially Regulate GABAA Receptor-Mediated Tonic Currents in Rat Hippocampal CA3 Pyramidal Neurons

GABAA Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets

GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes

Expression of calcium release-activated and voltage-gated calcium channels genes in peripheral blood mononuclear cells is altered in pregnancy and in type 1 diabetes

Functional Characterization of Native, High-Affinity GABAA Receptors in Human Pancreatic β Cells

ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function

Interferon-γ potentiates GABAA receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons

GLP-1 and exendin-4 transiently enhance GABAA receptor-mediated synaptic and tonic currents in rat hippocampal CA3 pyramidal neurons

Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

Tonic GABA‐activated synaptic and extrasynaptic currents in dentate gyrus granule cells and CA3 pyramidal neurons along the mouse hippocampal dorsoventral axis

Insulin enhances GABAA receptor-mediated inhibitory currents in rat central amygdala neurons

Single cell analysis of autism patient with bi-allelic NRXN1-alpha deletion reveals skewed fate choice in neural progenitors and impaired neuronal functionality

Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa

Insulin differentially modulates GABA signalling in hippocampal neurons and, in an age‐dependent manner, normalizes GABA‐activated currents in the tg‐APPSwe mouse model of Alzheimer’s disease

New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus

Insulin enhances GABA A receptor-mediated inhibitory currents in rat central amygdala neurons

In Intact Islets Interstitial GABA Activates GABAA Receptors That Generate Tonic Currents in α-Cells

AMPA, NMDA and kainate glutamate receptor subunits are expressed in human peripheral blood mononuclear cells (PBMCs) where the expression of GluK4 is altered by pregnancy and GluN2D by depression in pregnant women

Etomidate, propofol and diazepam potentiate GABA-evoked GABAA currents in a cell line derived from human glioblastoma

Normal human CD4+ helper T cells express Kv1.1 voltage-gated K+ channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway

In intact islets interstitial GABA activates GABA(A) receptors that generate tonic currents in α-cells

GABA A Receptor-Mediated Currents and Hormone mRNAs in Cells Expressing More Than One Hormone Transcript in Intact Human Pancreatic Islets

Interferon-γ potentiates GABA A receptor-mediated inhibitory currents in rat hippocampal CA1 pyramidal neurons

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