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Programmed death ligand 1 signals in cancer cells

Nature reviews. Cancer, 2022-03, Vol.22 (3), p.174-189

2022

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Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease

Virology (New York, N.Y.), 2015-02, Vol.476, p.196-205

2015

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Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease

Journal of virology, 2014-10, Vol.88 (20), p.11965-11972

2014

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Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications

Genome Biology, 2015-11, Vol.16 (1), p.257-257, Article 257

2015

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The complementarity of DDR, nucleic acids and anti-tumour immunity

Nature (London), 2023-07, Vol.619 (7970), p.475-486

2023

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Expression of CRISPR/Cas single guide RNAs using small tRNA promoters

RNA (Cambridge), 2015-09, Vol.21 (9), p.1683-1689

2015

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Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (50), p.E6945-E6954

2015

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Targeting hepatitis B virus cccDNA using CRISPR/Cas9

Antiviral research, 2015-11, Vol.123, p.188-192

2015

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Publisher Correction: Programmed death ligand 1 signals in cancer cells

Nature reviews. Cancer, 2022-03, Vol.22 (3), p.190-190

2022

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Programmed death ligand 1 signals in cancer cells

Nature reviews. Cancer, 2022-03, Vol.22 (3), p.174

2022

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Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators

Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (52), p.E7249-E7256

2015

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Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression

Cell host & microbe, 2016-05, Vol.19 (5), p.675-685

2016

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Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor-Induced Synthetic Lethality

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (11), p.2156-2170

2022

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Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy

Cancer medicine (Malden, MA), 2021-03, Vol.10 (6), p.2137-2152

2021

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Targeting HPV16 DNA using CRISPR/Cas inhibits anal cancer growth in vivo

Future virology, 2018-07, Vol.13 (7), p.475-482

2018

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Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects

Journal for immunotherapy of cancer, 2023-02, Vol.11 (2), p.e004871

2023

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Partial reconstitution of the RNAi response in human cells using Drosophila gene products

RNA (Cambridge), 2017-02, Vol.23 (2), p.153-160

2017

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Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic

Methods (San Diego, Calif.), 2015-12, Vol.91, p.82-86

2015

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Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents

International journal of molecular sciences, 2022-05, Vol.23 (9), p.5129

2022

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421 Specific cephalosporin antibiotics deplete tumor PD-L1 to inhibit DNA damage sensing and sensitize to Chk1 inhibitors in vivo

Journal of clinical and translational science, 2022-04, Vol.6 (s1), p.82-82

2022

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CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation

Journal for immunotherapy of cancer, 2021-04, Vol.9 (4), p.e002051

2021

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755 Pharmacologic tumor PD-L1 depletion reduces Chk2 content and sensitizes tumors to small molecule Chk1 DNA damage repair inhibitors

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A789-A790

2021

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Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression

Cell host & microbe, 2017-12, Vol.22 (6), p.830-830

2017

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298 Tumor cell-intrinsic mTORC1 signaling through raptor makes melanoma and ovarian cancer immunotherapy resistant by regulating interferon-gamma responsiveness and promoting tumor-initiating cells

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A321-A321

2021

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900 Depleting non-canonical, cell-intrinsic PD-L1 signals induces synthetic lethality to small molecule DNA damage response inhibitors in an immune independent and dependent manner

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A944-A944

2021

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Programmed death ligand 1 signals in cancer cells

Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease

Inactivation of the human papillomavirus E6 or E7 gene in cervical carcinoma cells by using a bacterial CRISPR/Cas RNA-guided endonuclease

Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications

The complementarity of DDR, nucleic acids and anti-tumour immunity

Expression of CRISPR/Cas single guide RNAs using small tRNA promoters

Production of functional small interfering RNAs by an amino-terminal deletion mutant of human Dicer

Targeting hepatitis B virus cccDNA using CRISPR/Cas9

Publisher Correction: Programmed death ligand 1 signals in cancer cells

Programmed death ligand 1 signals in cancer cells

Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators

Posttranscriptional m(6)A Editing of HIV-1 mRNAs Enhances Viral Gene Expression

Tumor Intrinsic PD-L1 Promotes DNA Repair in Distinct Cancers and Suppresses PARP Inhibitor-Induced Synthetic Lethality

Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy

Targeting HPV16 DNA using CRISPR/Cas inhibits anal cancer growth in vivo

Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects

Partial reconstitution of the RNAi response in human cells using Drosophila gene products

Optimization of a multiplex CRISPR/Cas system for use as an antiviral therapeutic

Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents

421 Specific cephalosporin antibiotics deplete tumor PD-L1 to inhibit DNA damage sensing and sensitize to Chk1 inhibitors in vivo

CD122-directed interleukin-2 treatment mechanisms in bladder cancer differ from αPD-L1 and include tissue-selective γδ T cell activation

755 Pharmacologic tumor PD-L1 depletion reduces Chk2 content and sensitizes tumors to small molecule Chk1 DNA damage repair inhibitors

Posttranscriptional m6A Editing of HIV-1 mRNAs Enhances Viral Gene Expression

298 Tumor cell-intrinsic mTORC1 signaling through raptor makes melanoma and ovarian cancer immunotherapy resistant by regulating interferon-gamma responsiveness and promoting tumor-initiating cells

900 Depleting non-canonical, cell-intrinsic PD-L1 signals induces synthetic lethality to small molecule DNA damage response inhibitors in an immune independent and dependent manner

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