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Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example

Rapid communications in mass spectrometry, 2011-12, Vol.25 (23), p.3587-3596

2011

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Advances in the integration of drug metabolism into the lead optimization paradigm

Mini reviews in medicinal chemistry, 2009-06, Vol.9 (6), p.703-716

Korfmacher, Walter A

2009

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Mass Spectrometry for Drug Discovery and Drug Development

Korfmacher, Walter A

1. Aufl., 2012

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It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS

Journal of mass spectrometry., 2011-06, Vol.46 (6), p.595-601

2011

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Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry

Journal of mass spectrometry., 2003-10, Vol.38 (10), p.1081-1092

2003

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Increasing speed and throughput when using HPLC-MS/MS systems for drug metabolism and pharmacokinetic screening

Current drug metabolism, 2006-06, Vol.7 (5), p.479

2006

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Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery

Rapid communications in mass spectrometry, 2003-01, Vol.17 (1), p.97-103

2003

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Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry

Journal of pharmacological and toxicological methods, 2007-03, Vol.55 (2), p.193-200

2007

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Optimization of definitive PPB using the RED device for a high binding compound at a low concentration

Drug metabolism and pharmacokinetics, 2018-01, Vol.33 (1), p.S23-S23

2018

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Chiral liquid chromatography-tandem mass spectrometric methods for stereoisomeric pharmaceutical determinations

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-06, Vol.820 (1), p.1-8

2005

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Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue

Rapid communications in mass spectrometry, 2006-03, Vol.20 (6), p.965-972

2006

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Development of a biomarker assay for 3-indoxyl sulfate in mouse plasma and brain by liquid chromatography/tandem mass spectrometry

Rapid communications in mass spectrometry, 2009-07, Vol.23 (13), p.2061-2069

2009

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The role of hyphenated chromatography-mass spectrometry techniques in exploratory drug metabolism and pharmacokinetics

Current pharmaceutical design, 2009-07, Vol.15 (19), p.2251-2261

2009

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Utility of capillary microsampling for rat pharmacokinetic studies: Comparison of tail-vein bleed to jugular vein cannula sampling

Journal of pharmacological and toxicological methods, 2015-11, Vol.76, p.7-14

2015

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Foundation review: Principles and applications of LC-MS in new drug discovery

Drug discovery today, 2005-10, Vol.10 (20), p.1357-1367

Korfmacher, Walter A.

2005

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High-resolution mass spectrometry will dramatically change our drug-discovery bioanalysis procedures

Bioanalysis, 2011-06, Vol.3 (11), p.1169-1171

Korfmacher, Walter

2011

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Mapping pharmaceuticals in rat brain sections using MALDI imaging mass spectrometry

Methods in molecular biology (Clifton, N.J.), 2010, Vol.656, p.147

2010

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High-Performance Liquid Chromatography-Atmospheric Pressure Photoionization/Tandem Mass Spectrometric Analysis for Small Molecules in Plasma

Analytical chemistry (Washington), 2003-07, Vol.75 (13), p.3122-3127

2003

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Supercritical Fluid Chromatography−Tandem Mass Spectrometry for the Enantioselective Determination of Propranolol and Pindolol in Mouse Blood by Serial Sampling

Analytical chemistry (Washington), 2006-02, Vol.78 (4), p.1212-1217

2006

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Investigation of the profiling depth in matrix-assisted laser desorption/ionization imaging mass spectrometry

Rapid communications in mass spectrometry, 2006-01, Vol.20 (2), p.284-290

2006

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High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometry for the detection of 17alpha-ethinylestradiol in hepatocytes

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-07, Vol.870 (2), p.186-191

2008

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Ultra-performance liquid chromatography/tandem mass spectrometric determination of testosterone and its metabolites in in vitro samples

Rapid communications in mass spectrometry, 2006-01, Vol.20 (14), p.2215-2221

2006

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Comparison of Atmospheric Pressure Chemical Ionization, Electrospray Ionization, and Atmospheric Pressure Photoionization for the Determination of Cyclosporin A in Rat Plasma

Analytical chemistry (Washington), 2005-01, Vol.77 (2), p.541-548

2005

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Direct Plasma Analysis of Drug Compounds Using Monolithic Column Liquid Chromatography and Tandem Mass Spectrometry

Analytical chemistry (Washington), 2003-04, Vol.75 (8), p.1812-1818

2003

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Fast mass spectrometry-based methodologies for pharmaceutical analyses

Combinatorial chemistry & high throughput screening, 2006-01, Vol.9 (1), p.3-8

2006

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Liquid extraction surface analysis mass spectrometry (LESA-MS) as a novel profiling tool for drug distribution and metabolism analysis: the terfenadine example

Advances in the integration of drug metabolism into the lead optimization paradigm

Mass Spectrometry for Drug Discovery and Drug Development

It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS

Direct analysis of drug candidates in tissue by matrix-assisted laser desorption/ionization mass spectrometry

Increasing speed and throughput when using HPLC-MS/MS systems for drug metabolism and pharmacokinetic screening

Investigation of matrix effects in bioanalytical high-performance liquid chromatography/tandem mass spectrometric assays: application to drug discovery

Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry

Optimization of definitive PPB using the RED device for a high binding compound at a low concentration

Chiral liquid chromatography-tandem mass spectrometric methods for stereoisomeric pharmaceutical determinations

Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue

Development of a biomarker assay for 3-indoxyl sulfate in mouse plasma and brain by liquid chromatography/tandem mass spectrometry

The role of hyphenated chromatography-mass spectrometry techniques in exploratory drug metabolism and pharmacokinetics

Utility of capillary microsampling for rat pharmacokinetic studies: Comparison of tail-vein bleed to jugular vein cannula sampling

Foundation review: Principles and applications of LC-MS in new drug discovery

High-resolution mass spectrometry will dramatically change our drug-discovery bioanalysis procedures

Mapping pharmaceuticals in rat brain sections using MALDI imaging mass spectrometry

High-Performance Liquid Chromatography-Atmospheric Pressure Photoionization/Tandem Mass Spectrometric Analysis for Small Molecules in Plasma

Supercritical Fluid Chromatography−Tandem Mass Spectrometry for the Enantioselective Determination of Propranolol and Pindolol in Mouse Blood by Serial Sampling

Investigation of the profiling depth in matrix-assisted laser desorption/ionization imaging mass spectrometry

High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometry for the detection of 17alpha-ethinylestradiol in hepatocytes

Ultra-performance liquid chromatography/tandem mass spectrometric determination of testosterone and its metabolites in in vitro samples

Comparison of Atmospheric Pressure Chemical Ionization, Electrospray Ionization, and Atmospheric Pressure Photoionization for the Determination of Cyclosporin A in Rat Plasma

Direct Plasma Analysis of Drug Compounds Using Monolithic Column Liquid Chromatography and Tandem Mass Spectrometry

Fast mass spectrometry-based methodologies for pharmaceutical analyses

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