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A Perspective on Multi-target Drugs for Alzheimer’s Disease

Trends in pharmacological sciences (Regular ed.), 2020-07, Vol.41 (7), p.434-445

2020

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Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy

Pharmacology & therapeutics (Oxford), 2020-06, Vol.210, p.107518, Article 107518

2020

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Adamantane - A Lead Structure for Drugs in Clinical Practice

Current medicinal chemistry, 2016-08, Vol.23 (29), p.3245

2016

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Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer

Cancers, 2021-02, Vol.13 (4), p.795

2021

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Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.41-71

2015

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Cholinesterase Research

Biomolecules (Basel, Switzerland), 2021-07, Vol.11 (8), p.1121

2021

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SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides

Archives of toxicology, 2016-12, Vol.90 (12), p.2831-2859

2016

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Chemical and Biological Threats, Hazard Potential and Countermeasures

Toxics (Basel), 2022-08, Vol.10 (8), p.444

2022

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Orexin supplementation in narcolepsy treatment: A review

Medicinal research reviews, 2019-05, Vol.39 (3), p.961-975

2019

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Newly Developed Drugs for Alzheimer’s Disease in Relation to Energy Metabolism, Cholinergic and Monoaminergic Neurotransmission

Neuroscience, 2018-02, Vol.370, p.191-206

2018

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Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists

Biomedicine & pharmacotherapy, 2024-07, Vol.176, p.116821, Article 116821

2024

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Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease

European journal of medicinal chemistry, 2017-02, Vol.127, p.250-262

2017

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Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease

Biomedicine & pharmacotherapy, 2024-04, Vol.173, p.116399-116399, Article 116399

2024

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Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease

Phytochemistry (Oxford), 2019-09, Vol.165, p.112055-112055, Article 112055

2019

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Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2237209-2237209

2023

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Profiling donepezil template into multipotent hybrids with antioxidant properties

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.583-606

2018

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A resurrection of 7-MEOTA: a comparison with tacrine

Current Alzheimer research, 2013-10, Vol.10 (8), p.893

2013

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A NEW SERIES OF PHARMACOLOGICAL DRUGS ACTING AT GLUN1/GLUN2A AND GLUN1/GLUN2B NMDA RECEPTORS

IBRO neuroscience reports, 2023-10, Vol.15, p.S426-S427

2023

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The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors

Scientific reports, 2020-10, Vol.10 (1), p.18576, Article 18576

2020

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7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies

Molecules (Basel, Switzerland), 2013-02, Vol.18 (2), p.2397-2418

2013

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Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease

International journal of molecular sciences, 2023-05, Vol.24 (11), p.9124

2023

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Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile

Molecules (Basel, Switzerland), 2022-02, Vol.27 (3), p.1060

2022

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Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2605-2620

2022

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Multi-spectroscopic monitoring of molecular interactions between an amino acid-functionalized ionic liquid and potential anti-Alzheimer's drugs

RSC advances, 2020-10, Vol.1 (64), p.38873-38883

2020

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A Perspective on Multi-target Drugs for Alzheimer’s Disease

Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy

Adamantane - A Lead Structure for Drugs in Clinical Practice

Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer

Phosphatidylinositol 3‑Kinase (PI3K) and Phosphatidylinositol 3‑Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Cholinesterase Research

SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides

Chemical and Biological Threats, Hazard Potential and Countermeasures

Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and Their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β‑d‑ribofuranose 2′-Oxidase

Orexin supplementation in narcolepsy treatment: A review

Newly Developed Drugs for Alzheimer’s Disease in Relation to Energy Metabolism, Cholinergic and Monoaminergic Neurotransmission

Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists

Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease

Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease

Amaryllidaceae alkaloids from Narcissus pseudonarcissus L. cv. Dutch Master as potential drugs in treatment of Alzheimer's disease

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

Profiling donepezil template into multipotent hybrids with antioxidant properties

A resurrection of 7-MEOTA: a comparison with tacrine

A NEW SERIES OF PHARMACOLOGICAL DRUGS ACTING AT GLUN1/GLUN2A AND GLUN1/GLUN2B NMDA RECEPTORS

The pathogenic S688Y mutation in the ligand-binding domain of the GluN1 subunit regulates the properties of NMDA receptors

7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies

Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease

Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N -Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile

Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities

Multi-spectroscopic monitoring of molecular interactions between an amino acid-functionalized ionic liquid and potential anti-Alzheimer's drugs

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