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Abuse liability of mitragynine assessed with a self-administration procedure in rats

Psychopharmacology, 2018-10, Vol.235 (10), p.2823-2829

2018

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Pharmacological Research as a Key Component in Mitigating the Opioid Overdose Crisis

Trends in pharmacological sciences (Regular ed.), 2018-12, Vol.39 (12), p.995-998

2018

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Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain

Nature communications, 2016-02, Vol.7 (1), p.10652-10652, Article 10652

2016

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Pharmacodynamics and pharmacokinetics of the novel synthetic opioid, U-47700, in male rats

Neuropharmacology, 2020-10, Vol.177, p.108195-108195, Article 108195

2020

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Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8808

2022

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Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats

The Journal of pharmacology and experimental therapeutics, 2014-01, Vol.348 (1), p.174-191

2014

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The Intriguing Effects of Substituents in the N -Phenethyl Moiety of Norhydromorphone: A Bifunctional Opioid from a Set of "Tail Wags Dog" Experiments

Molecules (Basel, Switzerland), 2020-06, Vol.25 (11), p.2640

2020

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Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists

The Journal of pharmacology and experimental therapeutics, 2016-07, Vol.358 (1), p.109

2016

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Cocaine-like neurochemical effects of antihistaminic medications

Journal of neurochemistry, 2008-07, Vol.106 (1), p.147-157

2008

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Sigma Receptor Agonists: Receptor Binding and Effects on Mesolimbic Dopamine Neurotransmission Assessed by Microdialysis

Biological psychiatry (1969), 2011-02, Vol.69 (3), p.208-217

2011

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Stimulants as specific inducers of dopamine-independent σ agonist self-administration in rats

The Journal of pharmacology and experimental therapeutics, 2013-10, Vol.347 (1), p.20-29

2013

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2-Substituted 3β-Aryltropane Cocaine Analogs Produce Atypical Effects without Inducing Inward-Facing Dopamine Transporter Conformations

The Journal of pharmacology and experimental therapeutics, 2016-03, Vol.356 (3), p.624

2016

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Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands

Medicinal chemistry research, 2020-09, Vol.29 (9), p.1697-1706

2020

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Identification of a Dopamine Transporter Ligand That Blocks the Stimulant Effects of Cocaine

The Journal of neuroscience, 2005-02, Vol.25 (8), p.1889-1893

2005

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2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter

The Journal of pharmacology and experimental therapeutics, 2014-05, Vol.349 (2), p.297-309

2014

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N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects

The Journal of pharmacology and experimental therapeutics, 2011-02, Vol.336 (2), p.575-585

2011

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Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change

Psychopharmacology, 2013-09, Vol.229 (2), p.307-321

2013

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Effects of muscarinic M1 receptor blockade on cocaine-induced elevations of brain dopamine levels and locomotor behavior in rats

The Journal of pharmacology and experimental therapeutics, 2007-04, Vol.321 (1), p.334

2007

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Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability

The Journal of pharmacology and experimental therapeutics, 2010-12, Vol.335 (3), p.703-714

2010

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Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands

The Journal of pharmacology and experimental therapeutics, 2004-05, Vol.309 (2), p.650-660

2004

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A Role for Sigma Receptors in Stimulant Self Administration and Addiction

Pharmaceuticals, 2011-06, Vol.4 (6), p.880-914

2011

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Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs

The Journal of pharmacology and experimental therapeutics, 2005-10, Vol.315 (1), p.397-404

2005

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Comparative structure-activity relationships of benztropine analogues at the dopamine transporter and histamine H1 receptors

Bioorganic & medicinal chemistry, 2006-06, Vol.14 (11), p.3625-3634

2006

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σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration

The Journal of pharmacology and experimental therapeutics, 2017-07, Vol.362 (1), p.2-13

2017

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Dopamine Transporter: Transmembrane Phenylalanine Mutations Can Selectively Influence Dopamine Uptake and Cocaine Analog Recognition

Molecular pharmacology, 1999-08, Vol.56 (2), p.434-447

1999

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Abuse liability of mitragynine assessed with a self-administration procedure in rats

Pharmacological Research as a Key Component in Mitigating the Opioid Overdose Crisis

Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brain

Pharmacodynamics and pharmacokinetics of the novel synthetic opioid, U-47700, in male rats

Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans

Preclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats

The Intriguing Effects of Substituents in the N -Phenethyl Moiety of Norhydromorphone: A Bifunctional Opioid from a Set of "Tail Wags Dog" Experiments

Blockade of Cocaine or σ Receptor Agonist Self Administration by Subtype-Selective σ Receptor Antagonists

Cocaine-like neurochemical effects of antihistaminic medications

Sigma Receptor Agonists: Receptor Binding and Effects on Mesolimbic Dopamine Neurotransmission Assessed by Microdialysis

Stimulants as specific inducers of dopamine-independent σ agonist self-administration in rats

2-Substituted 3β-Aryltropane Cocaine Analogs Produce Atypical Effects without Inducing Inward-Facing Dopamine Transporter Conformations

Exploring 1-adamantanamine as an alternative amine moiety for metabolically labile azepane ring in newly synthesized benzo[d]thiazol-2(3H)one σ receptor ligands

Identification of a Dopamine Transporter Ligand That Blocks the Stimulant Effects of Cocaine

2-isoxazol-3-phenyltropane derivatives of cocaine: molecular and atypical system effects at the dopamine transporter

N-substituted benztropine analogs: selective dopamine transporter ligands with a fast onset of action and minimal cocaine-like behavioral effects

Relations between stimulation of mesolimbic dopamine and place conditioning in rats produced by cocaine or drugs that are tolerant to dopamine transporter conformational change

Effects of muscarinic M1 receptor blockade on cocaine-induced elevations of brain dopamine levels and locomotor behavior in rats

Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability

Effects of N-substituted analogs of benztropine: diminished cocaine-like effects in dopamine transporter ligands

A Role for Sigma Receptors in Stimulant Self Administration and Addiction

Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs

Comparative structure-activity relationships of benztropine analogues at the dopamine transporter and histamine H1 receptors

σ Receptor Effects of N-Substituted Benztropine Analogs: Implications for Antagonism of Cocaine Self-Administration

Dopamine Transporter: Transmembrane Phenylalanine Mutations Can Selectively Influence Dopamine Uptake and Cocaine Analog Recognition

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