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Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

Nature (London), 2018-07, Vol.559 (7712), p.125-129

2018

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Design strategies for computational fragment-based drug design

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1289, p.137

Konteatis, Zenon D

2015

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In silico fragment-based drug design

Expert opinion on drug discovery, 2010-11, Vol.5 (11), p.1047-1065

Konteatis, Zenon D

2010

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Computational Approach to De Novo Discovery of Fragment Binding for Novel Protein States

Methods in Enzymology, 2011, Vol.493, p.357-380

2011

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Discovery and Development of Ivosidenib (AG‐120: TIBSOVO® )

Successful Drug Discovery, 2021, p.249-271

2021

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Arginine 206 of the C5a Receptor Is Critical for Ligand Recognition and Receptor Activation by C-terminal Hexapeptide Analogs (∗)

The Journal of biological chemistry, 1995-07, Vol.270 (27), p.15966-15969

1995

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d-Amino acid and alanine scans of the bioactive portion of porcine motilin

Peptides (New York, N.Y. : 1980), 1992-11, Vol.13 (6), p.1103-1107

1992

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Development of C5a receptor antagonists. Differential loss of functional responses

The Journal of immunology (1950), 1994-11, Vol.153 (9), p.4200-4205

1994

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The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs

The Journal of biological chemistry, 1994-05, Vol.269 (20), p.14446-14450

1994

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Capillary zone electrophoresis studies of motilin peptides: Effects of charge, hydrophobicity, secondary structure and length

Journal of Chromatography A, 1991-10, Vol.559 (1), p.391-399

1991

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Synthesis and in vitro evaluation of [Leu 13]porcine motilin fragments

Peptides (New York, N.Y. : 1980), 1992-05, Vol.13 (3), p.565-569

1992

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Capillary zone electrophoresis studies of motilin peptides

Journal of Chromatography A, 1991-10, Vol.559 (1-2), p.391-399

1991

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Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML

Blood advances, 2020-05, Vol.4 (9), p.1894-1905

2020

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Molecular Mechanisms Mediating Relapse Following Ivosidenib Monotherapy in Patients with IDH1-Mutant Relapsed or Refractory Acute Myeloid Leukemia

Blood, 2019-11, Vol.134 (Supplement_1), p.545-545

2019

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Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD)

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (23), p.7155-7165

2011

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Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor

Bioorganic & medicinal chemistry letters, 2005-03, Vol.15 (5), p.1401-1405

2005

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Mimicry of Erythropoietin by a Nonpeptide Molecule

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (21), p.12156-12161

1999

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Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations

Design strategies for computational fragment-based drug design

In silico fragment-based drug design

Computational Approach to De Novo Discovery of Fragment Binding for Novel Protein States

Discovery and Development of Ivosidenib (AG‐120: TIBSOVO® )

Arginine 206 of the C5a Receptor Is Critical for Ligand Recognition and Receptor Activation by C-terminal Hexapeptide Analogs (∗)

d-Amino acid and alanine scans of the bioactive portion of porcine motilin

Development of C5a receptor antagonists. Differential loss of functional responses

The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs

Capillary zone electrophoresis studies of motilin peptides: Effects of charge, hydrophobicity, secondary structure and length

Synthesis and in vitro evaluation of [Leu 13]porcine motilin fragments

Capillary zone electrophoresis studies of motilin peptides

AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations

Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML

Molecular Mechanisms Mediating Relapse Following Ivosidenib Monotherapy in Patients with IDH1-Mutant Relapsed or Refractory Acute Myeloid Leukemia

Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD)

Discovery and investigation of a novel class of thiophene-derived antagonists of the human glucagon receptor

Mimicry of Erythropoietin by a Nonpeptide Molecule

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