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Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases

Pharmacology & therapeutics (Oxford), 2018-03, Vol.183, p.177-204

2018

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Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids

Biochimica et biophysica acta, 2011, Vol.1814 (1), p.210-222

2011

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Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway[S]

Journal of lipid research, 2014-06, Vol.55 (6), p.1150-1164

2014

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CYP-eicosanoids—A new link between omega-3 fatty acids and cardiac disease?

Prostaglandins & other lipid mediators, 2011-11, Vol.96 (1), p.99-108

2011

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Amelioration of Endotoxemia by a Synthetic Analog of Omega-3 Epoxyeicosanoids

Frontiers in immunology, 2022-02, Vol.13, p.825171-825171

2022

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CYP2J2 overexpression protects against arrhythmia susceptibility in cardiac hypertrophy

PloS one, 2013-08, Vol.8 (8), p.e73490-e73490

2013

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Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease

Clinical and translational science, 2023-07, Vol.16 (7), p.1258-1271

2023

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CYP-Derived metabolites of Omega-3 fatty acids protect your heart

Journal of molecular and cellular cardiology, 2022-12, Vol.173, p.13-13

2022

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Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids

The Journal of biological chemistry, 2024-06, Vol.300 (6), p.107372, Article 107372

2024

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Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids

The Journal of biological chemistry, 2010-10, Vol.285 (43), p.32720-32733

2010

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Development of Robust 17(R),18(S)‑Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogues as Potential Clinical Antiarrhythmic Agents

Journal of medicinal chemistry, 2019-11, Vol.62 (22), p.10124-10143, Article acs.jmedchem.9b00952

2019

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Cytochrome P450–dependent metabolism of ω-6 and ω-3 long-chain polyunsaturated fatty acids

Pharmacological reports, 2010-05, Vol.62 (3), p.536-547

2010

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Einfluss von omega-3 fettsäuren auf die bildung physiologisch aktiver cyp-eicosanoide

Konkel, Anne

2016

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Cytochrome p450 enzymes in the bioactivation of polyunsaturated Fatty acids and their role in cardiovascular disease

Advances in experimental medicine and biology, 2015, Vol.851, p.151

2015

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17(R),18(S)-Epoxyeicosatetraenoic Acid, a Potent Eicosapentaenoic Acid (EPA) Derived Regulator of Cardiomyocyte Contraction: Structure–Activity Relationships and Stable Analogues

Journal of medicinal chemistry, 2011-06, Vol.54 (12), p.4109-4118

2011

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S.aureus haemolysin A-induced IL-8 and IL-6 release from human airway epithelial cells is mediated by activation of p38- and Erk-MAP kinases and additional, cell type-specific signalling mechanisms

Cellular microbiology, 2013-07, Vol.15 (7), p.1253

2013

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CYP-13A12 of the nematode Caenorhabditis elegans is a PUFA-epoxygenase involved in behavioural response to reoxygenation

Biochemical journal, 2014-11, Vol.464 (1), p.61-71

2014

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S. aureus haemolysin A‐induced IL‐8 and IL‐6 release from human airway epithelial cells is mediated by activation of p38‐ and Erk‐MAP kinases and additional, cell type‐specific signalling mechanisms

Cellular microbiology, 2013-07, Vol.15 (7), p.1253-1265

2013

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S. aureus haemolysin A-induced IL-8 and IL-6 release from human airway epithelial cells is mediated by activation of p38- and Erk-MAP kinases and additional, cell type-specific signalling mechanisms: Hla signalling and cytokine secretion by HAE cells

Cellular microbiology, 2013-07, Vol.15 (7), p.1253-1265

2013

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Abstract 631: Cardiomyocyte-specific Cyp4a12a Overexpression Aggravates Maladaptive Cardiac Hypertrophy

Hypertension (Dallas, Tex. 1979), 2012-09, Vol.60 (suppl_1)

2012

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Virulence factors of Staphylococcus aureus induce Erk-MAP kinase activation and c-Fos expression in S9 and 16HBE14o- human airway epithelial cells

American journal of physiology. Lung cellular and molecular physiology, 2009-03, Vol.296 (3), p.L470-L479

2009

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Abstract 607: Antiarrhythmic Effects Of Omega-3 Fatty Acids And Cyp-eicosanoids In A Murine Atrial Fibrillation Model

Hypertension (Dallas, Tex. 1979), 2012-09, Vol.60 (suppl_1)

2012

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Abstract 618: Dietary Omega-3 Fatty Acid Compete With Arachidonic Acid For The Formation Of Physiologically Active Cyp-eicosanoids In Man

Hypertension (Dallas, Tex. 1979), 2012-09, Vol.60 (suppl_1)

2012

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Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids

The Journal of biological chemistry, 2010-10, Vol.285 (43), p.32720-32733

2010

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Virulence factors of Staphylococcus aureus induce Erk-MAP kinase activation and c-Fos expression in S9 and 16HBE14o-human airway epithelial cells

American journal of physiology. Lung cellular and molecular physiology, 2009, Vol.40 (3)

2009

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Therapeutic potential of omega-3 fatty acid-derived epoxyeicosanoids in cardiovascular and inflammatory diseases

Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids

Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway[S]

CYP-eicosanoids—A new link between omega-3 fatty acids and cardiac disease?

Amelioration of Endotoxemia by a Synthetic Analog of Omega-3 Epoxyeicosanoids

CYP2J2 overexpression protects against arrhythmia susceptibility in cardiac hypertrophy

Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease

CYP-Derived metabolites of Omega-3 fatty acids protect your heart

Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids

Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids

Development of Robust 17(R),18(S)‑Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogues as Potential Clinical Antiarrhythmic Agents

Cytochrome P450–dependent metabolism of ω-6 and ω-3 long-chain polyunsaturated fatty acids

Einfluss von omega-3 fettsäuren auf die bildung physiologisch aktiver cyp-eicosanoide

Cytochrome p450 enzymes in the bioactivation of polyunsaturated Fatty acids and their role in cardiovascular disease

17(R),18(S)-Epoxyeicosatetraenoic Acid, a Potent Eicosapentaenoic Acid (EPA) Derived Regulator of Cardiomyocyte Contraction: Structure–Activity Relationships and Stable Analogues

S.aureus haemolysin A-induced IL-8 and IL-6 release from human airway epithelial cells is mediated by activation of p38- and Erk-MAP kinases and additional, cell type-specific signalling mechanisms

CYP-13A12 of the nematode Caenorhabditis elegans is a PUFA-epoxygenase involved in behavioural response to reoxygenation

S. aureus haemolysin A‐induced IL‐8 and IL‐6 release from human airway epithelial cells is mediated by activation of p38‐ and Erk‐MAP kinases and additional, cell type‐specific signalling mechanisms

S. aureus haemolysin A-induced IL-8 and IL-6 release from human airway epithelial cells is mediated by activation of p38- and Erk-MAP kinases and additional, cell type-specific signalling mechanisms: Hla signalling and cytokine secretion by HAE cells

Abstract 631: Cardiomyocyte-specific Cyp4a12a Overexpression Aggravates Maladaptive Cardiac Hypertrophy

Virulence factors of Staphylococcus aureus induce Erk-MAP kinase activation and c-Fos expression in S9 and 16HBE14o- human airway epithelial cells

Abstract 607: Antiarrhythmic Effects Of Omega-3 Fatty Acids And Cyp-eicosanoids In A Murine Atrial Fibrillation Model

Abstract 618: Dietary Omega-3 Fatty Acid Compete With Arachidonic Acid For The Formation Of Physiologically Active Cyp-eicosanoids In Man

Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of {omega}-3 fatty acids

Virulence factors of Staphylococcus aureus induce Erk-MAP kinase activation and c-Fos expression in S9 and 16HBE14o-human airway epithelial cells

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