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A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell

PLoS pathogens, 2022-02, Vol.18 (2), p.e1009977-e1009977

2022

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Plasmodium translocon component EXP2 facilitates hepatocyte invasion

Nature communications, 2020-11, Vol.11 (1), p.5654-5654, Article 5654

2020

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Characterisation of complexes formed by parasite proteins exported into the host cell compartment of Plasmodium falciparum infected red blood cells

Cellular microbiology, 2021-08, Vol.23 (8), p.e13332-n/a

2021

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Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150

Cellular microbiology, 2016-11, Vol.18 (11), p.1551-1569

2016

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Sequence elements within the PEXEL motif and its downstream region modulate PTEX‐dependent protein export in Plasmodium falciparum

Traffic (Copenhagen, Denmark), 2024-01, Vol.25 (1), p.e12922-n/a

2024

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Association of Inflammation and Immune Cell Infiltration with Estrogen Receptor Alpha in an Estrogen and Ionizing Radiation-Induced Breast Cancer Model

International journal of molecular sciences, 2024-08, Vol.25 (16), p.8604

2024

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The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture

Molecular microbiology, 2022-05, Vol.117 (5), p.1245-1262

2022

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Defining the Essential Exportome of the Malaria Parasite

Trends in parasitology, 2021-07, Vol.37 (7), p.664-675

2021

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Illuminating how malaria parasites export proteins into host erythrocytes

Cellular microbiology, 2019-04, Vol.21 (4), p.e13009-n/a

2019

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The malaria parasite Plasmodium falciparum Sortilin is essential for merozoite formation and apical complex biogenesis

Cellular microbiology, 2018-08, Vol.20 (8), p.e12844-n/a

2018

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The Plasmodium rhoptry associated protein complex is important for parasitophorous vacuole membrane structure and intraerythrocytic parasite growth

Cellular microbiology, 2017-08, Vol.19 (8), p.e12733-n/a

2017

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Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

eLife, 2017-03, Vol.6

2017

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Molecular approaches to Malaria 2020

Cellular microbiology, 2021-03, Vol.23 (3), p.e13289-n/a

2021

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Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

FEMS microbiology reviews, 2019-05, Vol.43 (3), p.223-238

2019

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The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host–parasite interface

The FEBS journal, 2018-06, Vol.285 (11), p.2037-2055

2018

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The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice

Cellular microbiology, 2016-03, Vol.18 (3), p.399-412

2016

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Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

eLife, 2022-09, Vol.11

2022

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The Plasmodium translocon of exported proteins (PTEX) component thioredoxin‐2 is important for maintaining normal blood‐stage growth

Molecular microbiology, 2013-09, Vol.89 (6), p.1167-1186

2013

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Role of NO and S-nitrosylation in the Expression of Endothelial Adhesion Proteins That Regulate Leukocyte and Tumor Cell Adhesion

Frontiers in physiology, 2020-11, Vol.11, p.595526-595526

2020

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The cysteine protease dipeptidyl aminopeptidase 3 does not contribute to egress of Plasmodium falciparum from host red blood cells

PloS one, 2018-03, Vol.13 (3), p.e0193538-e0193538

2018

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Contrasting Inducible Knockdown of the Auxiliary PTEX Component PTEX88 in P. falciparum and P. berghei Unmasks a Role in Parasite Virulence

PloS one, 2016-02, Vol.11 (2), p.e0149296

2016

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Altered gastrointestinal tract structure and microbiome following cerebral malaria infection

Parasitology research (1987), 2023-03, Vol.122 (3), p.789-799

2023

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How Malaria Parasites Acquire Nutrients From Their Host

Frontiers in cell and developmental biology, 2021-03, Vol.9, p.649184-649184

2021

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An aspartyl protease directs malaria effector proteins to the host cell

Nature (London), 2010-02, Vol.463 (7281), p.627-631

2010

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A revised mechanism for how Plasmodium falciparum recruits and exports proteins into its erythrocytic host cell

Plasmodium translocon component EXP2 facilitates hepatocyte invasion

Characterisation of complexes formed by parasite proteins exported into the host cell compartment of Plasmodium falciparum infected red blood cells

Proteomic analysis reveals novel proteins associated with the Plasmodium protein exporter PTEX and a loss of complex stability upon truncation of the core PTEX component, PTEX150

Sequence elements within the PEXEL motif and its downstream region modulate PTEX‐dependent protein export in Plasmodium falciparum

Association of Inflammation and Immune Cell Infiltration with Estrogen Receptor Alpha in an Estrogen and Ionizing Radiation-Induced Breast Cancer Model

The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture

Defining the Essential Exportome of the Malaria Parasite

Illuminating how malaria parasites export proteins into host erythrocytes

The malaria parasite Plasmodium falciparum Sortilin is essential for merozoite formation and apical complex biogenesis

The Plasmodium rhoptry associated protein complex is important for parasitophorous vacuole membrane structure and intraerythrocytic parasite growth

Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

Molecular approaches to Malaria 2020

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy

The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host–parasite interface

The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice

Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

The Plasmodium translocon of exported proteins (PTEX) component thioredoxin‐2 is important for maintaining normal blood‐stage growth

Role of NO and S-nitrosylation in the Expression of Endothelial Adhesion Proteins That Regulate Leukocyte and Tumor Cell Adhesion

The cysteine protease dipeptidyl aminopeptidase 3 does not contribute to egress of Plasmodium falciparum from host red blood cells

Contrasting Inducible Knockdown of the Auxiliary PTEX Component PTEX88 in P. falciparum and P. berghei Unmasks a Role in Parasite Virulence

Altered gastrointestinal tract structure and microbiome following cerebral malaria infection

How Malaria Parasites Acquire Nutrients From Their Host

Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4

An aspartyl protease directs malaria effector proteins to the host cell

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