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The Potential Use of Plant Natural Products and Plant Extracts with Antioxidant Properties for the Prevention/Treatment of Neurodegenerative Diseases: In Vitro, In Vivo and Clinical Trials

Molecules (Basel, Switzerland), 2018-12, Vol.23 (12), p.3283

2018

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GST-4-Dependent Suppression of Neurodegeneration in C. elegans Models of Parkinson’s and Machado-Joseph Disease by Rapeseed Pomace Extract Supplementation

Frontiers in neuroscience, 2019-10, Vol.13

2019

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Valorisation of Whisky Distillery Waste as a Sustainable Source of Antioxidant and Antibacterial Properties with Neuroprotective Potential

Waste and biomass valorization, 2024-04, Vol.15 (4), p.2333-2343

2024

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Experimental modelling of Alzheimer's disease for therapeutic screening

European journal of medicinal chemistry reports, 2022-08, Vol.5, p.100044, Article 100044

2022

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Current and emerging therapeutic targets of alzheimer's disease for the design of multi-target directed ligands

MedChemComm, 2019-12, Vol.1 (12), p.252-272

2019

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DNA profiling of single sperm cells after whole genome amplification

Forensic Science International. Reports, 2021-11, Vol.4, p.100240, Article 100240

2021

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Synthesis and in vitro evaluation of vanillin derivatives as multi-target therapeutics for the treatment of Alzheimer’s disease

Bioorganic & medicinal chemistry letters, 2020-11, Vol.30 (21), p.127505-127505, Article 127505

2020

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Novel vanillin derivatives: Synthesis, anti-oxidant, DNA and cellular protection properties

European journal of medicinal chemistry, 2018-01, Vol.143, p.745-754

2018

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The Use of Nano Polymeric Self-Assemblies Based on Novel Amphiphilic Polymers for Oral Hydrophobic Drug Delivery

Pharmaceutical research, 2012-03, Vol.29 (3), p.782-794

2012

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Determination of sinapine in rapeseed pomace extract: Its antioxidant and acetylcholinesterase inhibition properties

Food chemistry, 2019-03, Vol.276, p.768-775

2019

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Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression

Chemico-biological interactions, 2015-12, Vol.242, p.307-315

2015

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Thermally triggered theranostics for pancreatic cancer therapy

Nanoscale, 2017-09, Vol.9 (34), p.12735-12745

2017

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Study of a Novel Bisnaphthalimidopropyl Polyamine as Electroactive Material for Perchlorate-selective Potentiometric Sensors

Electroanalysis (New York, N.Y.), 2015-12, Vol.27 (12), p.2809-2819

2015

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Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells

Toxicology in vitro, 2018-10, Vol.52, p.342-350

2018

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Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: in vitro and in vivo studies

Nanomedicine (London, England), 2012-12, Vol.7 (12), p.1839-1849

2012

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Revalorisation of rapeseed pomace extracts: An in vitro study into its anti-oxidant and DNA protective properties

Food chemistry, 2018-01, Vol.239, p.323-332

2018

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In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa

International journal of antimicrobial agents, 2012-05, Vol.39 (5), p.424-430

2012

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Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease

MedChemComm, 2019-05, Vol.1 (5), p.764-777

2019

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Bisnaphthalimidopropyl Derivatives as Inhibitors of Leishmania SIR2 Related Protein 1

ChemMedChem, 2010-01, Vol.5 (1), p.140-147

2010

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A Novel PAA Derivative with Enhanced Drug Efficacy in Pancreatic Cancer Cell Lines

Pharmaceuticals (Basel, Switzerland), 2018-09, Vol.11 (4), p.91

2018

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Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells

European journal of medicinal chemistry, 2010-04, Vol.45 (4), p.1430-1437

2010

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Interaction between Amorphous Zirconia Nanoparticles and Graphite: Electrochemical Applications for Gallic Acid Sensing Using Carbon Paste Electrodes in Wine

Nanomaterials (Basel, Switzerland), 2020-03, Vol.10 (3), p.537

2020

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The synthesis and the in vitro cytotoxicity studies of bisnaphthalimidopropyl polyamine derivatives against colon cancer cells and parasite Leishmania infantum

Bioorganic & medicinal chemistry, 2007, Vol.15 (1), p.541-545

2007

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Novel bisnaphthalimidopropyl (BNIPs) derivatives as anticancer compounds targeting DNA in human breast cancer cells

Organic & biomolecular chemistry, 2016-10, Vol.14 (41), p.9780-9789

2016

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810 Preliminary safety, tolerability and efficacy results of KN026 in combination with KN046 in patients with HER2 aberrated solid tumors

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A485-A486

2020

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The Potential Use of Plant Natural Products and Plant Extracts with Antioxidant Properties for the Prevention/Treatment of Neurodegenerative Diseases: In Vitro, In Vivo and Clinical Trials

GST-4-Dependent Suppression of Neurodegeneration in C. elegans Models of Parkinson’s and Machado-Joseph Disease by Rapeseed Pomace Extract Supplementation

Valorisation of Whisky Distillery Waste as a Sustainable Source of Antioxidant and Antibacterial Properties with Neuroprotective Potential

Experimental modelling of Alzheimer's disease for therapeutic screening

Current and emerging therapeutic targets of alzheimer's disease for the design of multi-target directed ligands

DNA profiling of single sperm cells after whole genome amplification

Synthesis and in vitro evaluation of vanillin derivatives as multi-target therapeutics for the treatment of Alzheimer’s disease

Novel vanillin derivatives: Synthesis, anti-oxidant, DNA and cellular protection properties

The Use of Nano Polymeric Self-Assemblies Based on Novel Amphiphilic Polymers for Oral Hydrophobic Drug Delivery

Determination of sinapine in rapeseed pomace extract: Its antioxidant and acetylcholinesterase inhibition properties

Bisnaphthalimidopropyl diaminodicyclohexylmethane induces DNA damage and repair instability in triple negative breast cancer cells via p21 expression

Thermally triggered theranostics for pancreatic cancer therapy

Study of a Novel Bisnaphthalimidopropyl Polyamine as Electroactive Material for Perchlorate-selective Potentiometric Sensors

Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells

Characterization and evaluation of BNIPDaoct-loaded PLGA nanoparticles for visceral leishmaniasis: in vitro and in vivo studies

Revalorisation of rapeseed pomace extracts: An in vitro study into its anti-oxidant and DNA protective properties

In vitro evaluation of bisnaphthalimidopropyl derivatives loaded into pegylated nanoparticles against Leishmania infantum protozoa

Synthesis of novel vanillin derivatives: novel multi-targeted scaffold ligands against Alzheimer's disease

Bisnaphthalimidopropyl Derivatives as Inhibitors of Leishmania SIR2 Related Protein 1

A Novel PAA Derivative with Enhanced Drug Efficacy in Pancreatic Cancer Cell Lines

Synthesis, cytotoxicity and DNA-binding of novel bisnaphthalimidopropyl derivatives in breast cancer MDA-MB-231 cells

Interaction between Amorphous Zirconia Nanoparticles and Graphite: Electrochemical Applications for Gallic Acid Sensing Using Carbon Paste Electrodes in Wine

The synthesis and the in vitro cytotoxicity studies of bisnaphthalimidopropyl polyamine derivatives against colon cancer cells and parasite Leishmania infantum

Novel bisnaphthalimidopropyl (BNIPs) derivatives as anticancer compounds targeting DNA in human breast cancer cells

810 Preliminary safety, tolerability and efficacy results of KN026 in combination with KN046 in patients with HER2 aberrated solid tumors

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