UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 28

Sortiert nach

Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.512-516

2015

Link zum Volltext

Verfügbarkeit prüfen

Bruton’s Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies

Journal of medicinal chemistry, 2012-05, Vol.55 (10), p.4539-4550

2012

Link zum Volltext

Verfügbarkeit prüfen

Kinetic and thermodynamic assessment of binding of serotonin transporter inhibitors

The Journal of pharmacology and experimental therapeutics, 2008-12, Vol.327 (3), p.991

2008

Link zum Volltext

Verfügbarkeit prüfen

Atomic Contributions to the Optical Rotation Angle as a Quantitative Probe of Molecular Chirality

Science (American Association for the Advancement of Science), 1998-12, Vol.282 (5397), p.2247-2250

1998

Link zum Volltext

Verfügbarkeit prüfen

Optical Rotation Computation, Total Synthesis, and Stereochemistry Assignment of the Marine Natural Product Pitiamide A

Journal of the American Chemical Society, 2000-05, Vol.122 (19), p.4608-4617

2000

Link zum Volltext

Verfügbarkeit prüfen

Theory-Assisted Determination of Absolute Stereochemistry for Complex Natural Products via Computation of Molar Rotation Angles

Journal of the American Chemical Society, 1998-03, Vol.120 (9), p.2204-2205

1998

Link zum Volltext

Verfügbarkeit prüfen

Finding the perfect spot for fluorine: improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold

Bioorganic & medicinal chemistry letters, 2015-01, Vol.25 (2), p.367-371

2015

Link zum Volltext

Verfügbarkeit prüfen

Hepatitis C Virus NS5B Polymerase: QM/MM Calculations Show the Important Role of the Internal Energy in Ligand Binding

The journal of physical chemistry. B, 2008-03, Vol.112 (10), p.3168-3176

2008

Link zum Volltext

Verfügbarkeit prüfen

Determining Absolute Configuration in Flexible Molecules: A Case Study

Journal of the American Chemical Society, 2001-09, Vol.123 (37), p.8961-8966

2001

Link zum Volltext

Verfügbarkeit prüfen

Structural and Conformational Dependence of Optical Rotation Angles

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 1999-08, Vol.103 (33), p.6603-6611

1999

Link zum Volltext

Verfügbarkeit prüfen

New peroxylactones from the Jamaican sponge Plakinastrella onkodes, with inhibitory activity against the AIDS opportunistic parasitic infection Toxoplasma gondii

Tetrahedron, 2001-02, Vol.57 (8), p.1483-1487

2001

Link zum Volltext

Verfügbarkeit prüfen

Chiral Action at a Distance: Remote Substituent Effects on the Optical Activity of Calyculins A and B

Organic letters, 2000-06, Vol.2 (11), p.1509-1512

2000

Link zum Volltext

Verfügbarkeit prüfen

Hepatitis C Virus NS5B Polymerase: QM/MM Calculations Show the Important Role of the Internal Energy in Ligand Binding

The journal of physical chemistry. B, 2008-01, Vol.112 (10), p.3168-3176

2008

Link zum Volltext

Verfügbarkeit prüfen

Interactions at the human ether a go‐go (hERG) potassium channel investigated through multiple radioligands

The FASEB journal, 2006-03, Vol.20 (5), p.A1112-A1112

2006

Link zum Volltext

Verfügbarkeit prüfen

CCR5 antagonists have different conformational requirements for the transition to the most thermodynamically stable CCR5 receptor:antagonist complex

The FASEB journal, 2006-03, Vol.20 (5), p.A918-A919

2006

Link zum Volltext

Verfügbarkeit prüfen

Alchemy 2000

Science (American Association for the Advancement of Science), 2000-06, Vol.288 (5473), p.1981-1981

2000

Link zum Volltext

Verfügbarkeit prüfen

Determination of the absolute configuration of 1,3,5,7-tetramethyl-1,3-dihydroindol-2-one by optical rotation computation

Tetrahedron: asymmetry, 1999-10, Vol.10 (21), p.4143-4150

1999

Link zum Volltext

Verfügbarkeit prüfen

Atomic contributions to the optical rotation angle as a quantitative probe of molecular chiarlity

Science (American Association for the Advancement of Science), 1998-12, Vol.282 (5397), p.2247-2250

1998

Link zum Volltext

Verfügbarkeit prüfen

Synthetic and model computational studies of molar rotation additivity for interacting chiral centers: A reinvestigation of van't Hoff's principle

Chirality (New York, N.Y.), 1997, Vol.9 (5-6), p.469-477

1997

Link zum Volltext

Verfügbarkeit prüfen

Turning Structures into Gold

Science, 2000, Vol.288 (5473), p.1981-1982

2000

Link zum Volltext

Verfügbarkeit prüfen

ChemInform Abstract: Optical Rotation Computation, Total Synthesis, and Stereochemistry Assignment of the Marine Natural Product Pitiamide A

ChemInform, 2000-08, Vol.31 (34), p.no-no

2000

Link zum Volltext

Verfügbarkeit prüfen

ChemInform Abstract: Chiral Action at a Distance: Remote Substituent Effects on the Optical Activity of Calyculins A and B

ChemInform, 2000-08, Vol.31 (35), p.no-no

2000

Link zum Volltext

Verfügbarkeit prüfen

Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Journal of medicinal chemistry, 2012-09, Vol.55 (17), p.7686-7695

2012

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition

Journal of medicinal chemistry, 2012-06, Vol.55 (12), p.5887-5900

2012

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 28

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(25)
Mit Volltextzugriff
(27)

Publikationsform

Artikel
(27)
Reviews
(1)

Sprache

Englisch
(28)
Japanisch
(4)

Erscheinungsjahr

n.n

Thema

Science & Technology
(18)
Chemistry
(13)
Physical Sciences
(12)
Life Sciences & Biomedicine
(8)
Pharmacology & Pharmacy
(8)
Chemistry, Medicinal
(7)
Chemistry, Organic
(7)
Models, Molecular
(7)
Humans
(5)
Crystallography, X-Ray
(4)
Molecular Structure
(4)
Stereochemistry
(4)
Stereoisomerism
(4)
Chemistry, Multidisciplinary
(3)
Chemistry, Physical
(3)
Models, Chemical
(3)
Molecular Conformation
(3)
Molecules
(3)
Phosphatidylinositol 3-Kinases - Antagonists & Inhibitors
(3)
Physics
(3)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis

Bruton’s Tyrosine Kinase Inhibitors: Approaches to Potent and Selective Inhibition, Preclinical and Clinical Evaluation for Inflammatory Diseases and B Cell Malignancies

Kinetic and thermodynamic assessment of binding of serotonin transporter inhibitors

Atomic Contributions to the Optical Rotation Angle as a Quantitative Probe of Molecular Chirality

Optical Rotation Computation, Total Synthesis, and Stereochemistry Assignment of the Marine Natural Product Pitiamide A

Theory-Assisted Determination of Absolute Stereochemistry for Complex Natural Products via Computation of Molar Rotation Angles

Finding the perfect spot for fluorine: improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold

Hepatitis C Virus NS5B Polymerase: QM/MM Calculations Show the Important Role of the Internal Energy in Ligand Binding

Determining Absolute Configuration in Flexible Molecules: A Case Study

Structural and Conformational Dependence of Optical Rotation Angles

New peroxylactones from the Jamaican sponge Plakinastrella onkodes, with inhibitory activity against the AIDS opportunistic parasitic infection Toxoplasma gondii

Chiral Action at a Distance: Remote Substituent Effects on the Optical Activity of Calyculins A and B

Hepatitis C Virus NS5B Polymerase: QM/MM Calculations Show the Important Role of the Internal Energy in Ligand Binding

Interactions at the human ether a go‐go (hERG) potassium channel investigated through multiple radioligands

CCR5 antagonists have different conformational requirements for the transition to the most thermodynamically stable CCR5 receptor:antagonist complex

Alchemy 2000

Determination of the absolute configuration of 1,3,5,7-tetramethyl-1,3-dihydroindol-2-one by optical rotation computation

Atomic contributions to the optical rotation angle as a quantitative probe of molecular chiarlity

Synthetic and model computational studies of molar rotation additivity for interacting chiral centers: A reinvestigation of van't Hoff's principle

Turning Structures into Gold

ChemInform Abstract: Optical Rotation Computation, Total Synthesis, and Stereochemistry Assignment of the Marine Natural Product Pitiamide A

ChemInform Abstract: Chiral Action at a Distance: Remote Substituent Effects on the Optical Activity of Calyculins A and B

Potent and Highly Selective Benzimidazole Inhibitors of PI3-Kinase Delta

Discovery of Novel PI3-Kinase δ Specific Inhibitors for the Treatment of Rheumatoid Arthritis: Taming CYP3A4 Time-Dependent Inhibition

Potent and selective inhibitors of PI3Kδ: Obtaining isoform selectivity from the affinity pocket and tryptophan shelf

Suchergebnisse filtern