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p53 and the Carcinogenicity of Chronic Inflammation

Cold Spring Harbor perspectives in medicine, 2016-11, Vol.6 (11), p.a026161

2016

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p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.E89-E98

2013

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The role of p53 in determining sensitivity to radiotherapy

Nature reviews. Cancer, 2003-02, Vol.3 (2), p.117-129

2003

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Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation

Nature chemical biology, 2006-09, Vol.2 (9), p.474-479

2006

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Prospective therapeutic applications of p53 inhibitors

Biochemical and biophysical research communications, 2005-06, Vol.331 (3), p.726-736

2005

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Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53

Cell death & disease, 2021-05, Vol.12 (6), p.545-545, Article 545

2021

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Dangerous habits of a security guard: the two faces of p53 as a drug target

Human molecular genetics, 2007-04, Vol.16 (R1), p.R67-R72

2007

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p53 is a suppressor of inflammatory response in mice

The FASEB journal, 2005-06, Vol.19 (8), p.1030-1032

2005

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Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice

Oncogene, 2004-04, Vol.23 (19), p.3265-3271

2004

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A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice

Cell cycle (Georgetown, Tex.), 2010-04, Vol.9 (7), p.1434-1443

2010

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Pathologies associated with the p53 response

Cold Spring Harbor perspectives in biology, 2010-07, Vol.2 (7), p.a001180-a001180

2010

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Radioprotection: smart games with death

The Journal of clinical investigation, 2010-07, Vol.120 (7), p.2270-2273

2010

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Inflammation and p53: A Tale of Two Stresses

Genes & cancer, 2011-04, Vol.2 (4), p.503-516

2011

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Different impact of p53 and p21 on the radiation response of mouse tissues

Oncogene, 2000-08, Vol.19 (33), p.3791-3798

2000

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Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/- mice

Aging (Albany, NY.), 2012-10, Vol.4 (10), p.709-714

2012

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Stress-induced secretion of growth inhibitors : a novel tumor suppressor function of p53

Oncogene, 1998-09, Vol.17 (9), p.1089-1096

1998

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A Chemical Inhibitor of p53 that Protects Mice from the Side Effects of Cancer Therapy

Science (American Association for the Advancement of Science), 1999-09, Vol.285 (5434), p.1733-1737

1999

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Dysregulation of the mTOR pathway in p53-deficient mice

Cancer biology & therapy, 2013-12, Vol.14 (12), p.1182-1188

2013

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Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

Blood, 2010-02, Vol.115 (5), p.1088-1097

2010

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ATM is activated in blood monocytes after tumor radiation

Oncotarget, 2013-08, Vol.4 (8), p.1125-1125

2013

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p53 Inhibitor Pifithrin α Can Suppress Heat Shock and Glucocorticoid Signaling Pathways

The Journal of biological chemistry, 2003-05, Vol.278 (18), p.15465-15468

2003

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Inhibition of p53 response in tumor stroma improves efficacy of anticancer treatment by increasing antiangiogenic effects of chemotherapy and radiotherapy in mice

Cancer research (Chicago, Ill.), 2006-10, Vol.66 (19), p.9356-9361

2006

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Chemoprotection from p53-dependent apoptosis : potential clinical applications of the p53 inhibitors

Biochemical pharmacology, 2001-09, Vol.62 (6), p.657-667

2001

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Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

The EMBO journal, 1997-03, Vol.16 (6), p.1391-1400

1997

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Aggregation of dextran hydrophobically modified by sterically-hindered phenols in aqueous solutions: Aggregates vs. single molecules

European polymer journal, 2008-10, Vol.44 (10), p.3361-3369

2008

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p53 and the Carcinogenicity of Chronic Inflammation

p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

The role of p53 in determining sensitivity to radiotherapy

Small-molecule inhibitor of p53 binding to mitochondria protects mice from gamma radiation

Prospective therapeutic applications of p53 inhibitors

Resistance of bone marrow stroma to genotoxic preconditioning is determined by p53

Dangerous habits of a security guard: the two faces of p53 as a drug target

p53 is a suppressor of inflammatory response in mice

Dual effect of p53 on radiation sensitivity in vivo: p53 promotes hematopoietic injury, but protects from gastro-intestinal syndrome in mice

A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice

Pathologies associated with the p53 response

Radioprotection: smart games with death

Inflammation and p53: A Tale of Two Stresses

Different impact of p53 and p21 on the radiation response of mouse tissues

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/- mice

Stress-induced secretion of growth inhibitors : a novel tumor suppressor function of p53

A Chemical Inhibitor of p53 that Protects Mice from the Side Effects of Cancer Therapy

Dysregulation of the mTOR pathway in p53-deficient mice

Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation

ATM is activated in blood monocytes after tumor radiation

p53 Inhibitor Pifithrin α Can Suppress Heat Shock and Glucocorticoid Signaling Pathways

Inhibition of p53 response in tumor stroma improves efficacy of anticancer treatment by increasing antiangiogenic effects of chemotherapy and radiotherapy in mice

Chemoprotection from p53-dependent apoptosis : potential clinical applications of the p53 inhibitors

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

Aggregation of dextran hydrophobically modified by sterically-hindered phenols in aqueous solutions: Aggregates vs. single molecules

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