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Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

Life sciences (1973), 2016-03, Vol.148, p.183-193

2016

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Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells

Breast cancer research : BCR, 2019-09, Vol.21 (1), p.104-104, Article 104

2019

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Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance

Cancers, 2015-11, Vol.7 (4), p.2330-2351

2015

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Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer

Breast cancer research : BCR, 2023-04, Vol.25 (1), p.44-44, Article 44

2023

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A Novel Role for BRIP1/FANCJ in Neuronal Cells Health and in Resolving Oxidative Stress-Induced DNA Lesions

Journal of Alzheimer's disease, 2022-01, Vol.85 (1), p.207-221

2022

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The multifunctional protein PACS-1 is required for HDAC2- and HDAC3-dependent chromatin maturation and genomic stability

Oncogene, 2020-03, Vol.39 (12), p.2583-2596

2020

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ALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signaling

PloS one, 2014-09, Vol.9 (9), p.e107142

2014

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Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers

PloS one, 2020, Vol.15 (7), p.e0236291-e0236291

2020

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Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition

Neoplasia (New York, N.Y.), 2018-12, Vol.20 (12), p.1236-1245

2018

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Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle

PloS one, 2019-11, Vol.14 (11), p.e0225775-e0225775

2019

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Corrigendum to “Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition.” [Neoplasia Volume 23, Issue 9, September 2021, Pages 1002-1015]

Neoplasia (New York, N.Y.), 2024-04, Vol.50, p.100978-100978, Article 100978

2024

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Disparities in Breast Cancer Survivors in Rural West Texas

Cancer control, 2021, Vol.28, p.10732748211042125-10732748211042125

2021

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Enhanced Therapeutic Efficacy of the Nanoscale Fluoropyrimidine Polymer CF10 in a Rat Colorectal Cancer Liver Metastasis Model

Cancers, 2024-04, Vol.16 (7), p.1360

2024

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Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression

PloS one, 2018-02, Vol.13 (2), p.e0192421

2018

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Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition

Neoplasia (New York, N.Y.), 2021-09, Vol.23 (9), p.1002-1015

2021

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Antitumour drugs impede DNA uncoiling by topoisomerase I

Nature, 2007-07, Vol.448 (7150), p.213-217

2007

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GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

Oncotarget, 2014-12, Vol.5 (23), p.12151-12165

2014

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The role of tumour suppressor PDCD4 in beta cell death in hypoxia

PloS one, 2017-07, Vol.12 (7), p.e0181235-e0181235

2017

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Escherichia coli DNA ligase B may mitigate damage from oxidative stress

PloS one, 2017-07, Vol.12 (7), p.e0180800-e0180800

2017

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Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics

Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (1), p.9137629-9137629

2016

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Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway

The Journal of biological chemistry, 2010-10, Vol.285 (41), p.31525-31536

2010

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Renal Lipid Metabolism Abnormalities in Obesity and Clear Cell Renal Cell Carcinoma

Metabolites, 2021-09, Vol.11 (9), p.608

2021

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Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome

PloS one, 2015-11, Vol.10 (11), p.e0142218-e0142218

2015

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Mutations at the Subunit Interface of Yeast Proliferating Cell Nuclear Antigen Reveal a Versatile Regulatory Domain

PloS one, 2016-08, Vol.11 (8), p.e0161307

2016

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CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer

Cell death discovery, 2024-06, Vol.10 (1), p.278-15

2024

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Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

Prexasertib treatment induces homologous recombination deficiency and synergizes with olaparib in triple-negative breast cancer cells

Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance

Racial differences in RAD51 expression are regulated by miRNA-214-5P and its inhibition synergizes with olaparib in triple-negative breast cancer

A Novel Role for BRIP1/FANCJ in Neuronal Cells Health and in Resolving Oxidative Stress-Induced DNA Lesions

The multifunctional protein PACS-1 is required for HDAC2- and HDAC3-dependent chromatin maturation and genomic stability

ALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signaling

Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers

Thymineless Death by the Fluoropyrimidine Polymer F10 Involves Replication Fork Collapse and Is Enhanced by Chk1 Inhibition

Differential phosphorylation determines the repressor and activator potencies of GLI1 proteins and their efficiency in modulating the HPV life cycle

Corrigendum to “Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition.” [Neoplasia Volume 23, Issue 9, September 2021, Pages 1002-1015]

Disparities in Breast Cancer Survivors in Rural West Texas

Enhanced Therapeutic Efficacy of the Nanoscale Fluoropyrimidine Polymer CF10 in a Rat Colorectal Cancer Liver Metastasis Model

Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression

Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition

Antitumour drugs impede DNA uncoiling by topoisomerase I

GLI inhibitor GANT-61 diminishes embryonal and alveolar rhabdomyosarcoma growth by inhibiting Shh/AKT-mTOR axis

The role of tumour suppressor PDCD4 in beta cell death in hypoxia

Escherichia coli DNA ligase B may mitigate damage from oxidative stress

Oxidative Stress in Metabolic Disorders: Pathogenesis, Prevention, and Therapeutics

Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway

Renal Lipid Metabolism Abnormalities in Obesity and Clear Cell Renal Cell Carcinoma

Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome

Mutations at the Subunit Interface of Yeast Proliferating Cell Nuclear Antigen Reveal a Versatile Regulatory Domain

CHK1 inhibitor induced PARylation by targeting PARG causes excessive replication and metabolic stress and overcomes chemoresistance in ovarian cancer

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