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Nanobodies targeting the hepatocyte growth factor: potential new drugs for molecular cancer therapy

Molecular cancer therapeutics, 2012-04, Vol.11 (4), p.1017-1025

2012

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A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein

mBio, 2024-01, Vol.15 (1), p.e0212223-e0212223

2024

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Directed evolution of proteins by exon shuffling

Nature biotechnology, 2001-05, Vol.19 (5), p.423-428

2001

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Nanobodies – from llamas to therapeutic proteins

Drug discovery today. Technologies, 2010, Vol.7 (2), p.e139-e146

2010

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Insertion Loop 256−268 in Coagulation Factor IX Restricts Enzymatic Activity in the Absence but Not in the Presence of Factor VIII

Biochemistry (Easton), 2000-06, Vol.39 (25), p.7398-7405

2000

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Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6414), p.598-602

2018

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Factor VIII-factor IX interactions: molecular sites involved in enzyme-cofactor complex assembly

Thrombosis and haemostasis, 1999-08, Vol.82 (2), p.209

1999

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Molecular evolution of mammalian ribonucleases 1

Molecular phylogenetics and evolution, 2003-06, Vol.27 (3), p.453-463

2003

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Residues Phe342-Asn346 of activated coagulation factor IX contribute to the interaction with low density lipoprotein receptor-related protein

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9394-9401

2003

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Universal Protection against Influenza Infection by a Multi-Domain Antibody to Influenza Hemagglutinin

Science (American Association for the Advancement of Science), 2018-11, Vol.362 (6414), p.598-602

2018

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Regions 301–303 and 333–339 in the catalytic domain of blood coagulation Factor IX are Factor VIII-interactive sites involved in stimulation of enzyme activity

Biochemical journal, 1999-04, Vol.339 (2), p.217-221

1999

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Blood Coagulation Factor IX Residues Glu78 and Arg94 Provide a Link between Both Epidermal Growth Factor-like Domains That Is Crucial in the Interaction with Factor VIII Light Chain

The Journal of biological chemistry, 1998-01, Vol.273 (1), p.222-227

1998

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Regions 301-303 and 333-339 in the catalytic domain of blood coagulation factor IX are factor VIII-interactive sites involved in stimulation of enzyme activity

Biochemical journal, 1999-04, Vol.339 ( Pt 2) (2), p.217-221

1999

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Surface-loop residue Lys316 in blood coagulation Factor IX is a major determinant for Factor X but not antithrombin recognition

Biochemical journal, 2000-09, Vol.350 (3), p.701-707

2000

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Surface-loop residue Lys316 in blood coagulation Factor IX is a major determinant for Factor X but not antithrombin recognition

Biochemical journal, 2000-09, Vol.350 Pt 3 (3), p.701-707

2000

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Residues Phe342âAsn346 of Activated Coagulation Factor IX Contribute to the Interaction with Low Density Lipoprotein Receptor-related Protein

The Journal of biological chemistry, 2003-03, Vol.278 (11), p.9394

2003

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Surface Loop 199–204 in Blood Coagulation Factor IX Is a Cofactor-dependent Site Involved in Macromolecular Substrate Interaction

The Journal of biological chemistry, 1999-10, Vol.274 (41), p.29087-29093

1999

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Surface Loop 199â204 in Blood Coagulation Factor IX Is a Cofactor-dependent Site Involved in Macromolecular Substrate Interaction

The Journal of biological chemistry, 1999-10, Vol.274 (41), p.29087

1999

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On the two iron centers of desulfoferrodoxin

FEBS letters, 1993-12, Vol.336 (1), p.13-18

1993

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The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis

Arthritis research & therapy, 2015-05, Vol.17 (1), p.135-135, Article 135

2015

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Bladder Function Preservation With Brachytherapy, External Beam Radiation Therapy, and Limited Surger in Bladder Cancer Patients: Long-Term Results

International journal of radiation oncology, biology, physics, 2014-03, Vol.88 (3), p.611-617

2014

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Toxicity and quality of life after high-dose-rate brachytherapy as monotherapy for low- and intermediate-risk prostate cancer

Radiotherapy and oncology, 2015-11, Vol.117 (2), p.252-257

2015

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Added value of chest computed tomography in suspected COVID-19: an analysis of 239 patients

The European respiratory journal, 2020-08, Vol.56 (2), p.2001377

2020

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Nanobodies targeting the hepatocyte growth factor: potential new drugs for molecular cancer therapy

A neutralizing single-domain antibody that targets the trimer interface of the human metapneumovirus fusion protein

Directed evolution of proteins by exon shuffling

Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction

Nanobodies – from llamas to therapeutic proteins

Insertion Loop 256−268 in Coagulation Factor IX Restricts Enzymatic Activity in the Absence but Not in the Presence of Factor VIII

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Factor VIII-factor IX interactions: molecular sites involved in enzyme-cofactor complex assembly

Molecular evolution of mammalian ribonucleases 1

Residues Phe342-Asn346 of activated coagulation factor IX contribute to the interaction with low density lipoprotein receptor-related protein

Universal Protection against Influenza Infection by a Multi-Domain Antibody to Influenza Hemagglutinin

Regions 301–303 and 333–339 in the catalytic domain of blood coagulation Factor IX are Factor VIII-interactive sites involved in stimulation of enzyme activity

Blood Coagulation Factor IX Residues Glu78 and Arg94 Provide a Link between Both Epidermal Growth Factor-like Domains That Is Crucial in the Interaction with Factor VIII Light Chain

Regions 301-303 and 333-339 in the catalytic domain of blood coagulation factor IX are factor VIII-interactive sites involved in stimulation of enzyme activity

Surface-loop residue Lys316 in blood coagulation Factor IX is a major determinant for Factor X but not antithrombin recognition

Surface-loop residue Lys316 in blood coagulation Factor IX is a major determinant for Factor X but not antithrombin recognition

Residues Phe342âAsn346 of Activated Coagulation Factor IX Contribute to the Interaction with Low Density Lipoprotein Receptor-related Protein

Surface Loop 199–204 in Blood Coagulation Factor IX Is a Cofactor-dependent Site Involved in Macromolecular Substrate Interaction

Surface Loop 199â204 in Blood Coagulation Factor IX Is a Cofactor-dependent Site Involved in Macromolecular Substrate Interaction

On the two iron centers of desulfoferrodoxin

Multivalent nanobodies targeting death receptor 5 elicit superior tumor cell killing through efficient caspase induction

The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis

Bladder Function Preservation With Brachytherapy, External Beam Radiation Therapy, and Limited Surger in Bladder Cancer Patients: Long-Term Results

Toxicity and quality of life after high-dose-rate brachytherapy as monotherapy for low- and intermediate-risk prostate cancer

Added value of chest computed tomography in suspected COVID-19: an analysis of 239 patients

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