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Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

Science (American Association for the Advancement of Science), 2010-01, Vol.327 (5963), p.348-351

2010

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Rapid behavior-based identification of neuroactive small molecules in the zebrafish

Nature chemical biology, 2010-03, Vol.6 (3), p.231-237

2010

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Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

Nature communications, 2021-09, Vol.12 (1), p.5284-5284, Article 5284

2021

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Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation

Nature communications, 2019-09, Vol.10 (1), p.4078-14, Article 4078

2019

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Identification of nonvisual photomotor response cells in the vertebrate hindbrain

The Journal of neuroscience, 2013-02, Vol.33 (9), p.3834-3843

2013

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Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology

ACS chemical biology, 2016-04, Vol.11 (4), p.842-849

2016

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Chemical informatics and target identification in a zebrafish phenotypic screen

Nature chemical biology, 2011-12, Vol.8 (2), p.144-146

2011

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The nongenotoxic carcinogens naphthalene and para -dichlorobenzene suppress apoptosis in Caenorhabditis elegans

Nature chemical biology, 2006-06, Vol.2 (6), p.338-345

2006

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A non-hallucinogenic psychedelic analogue with therapeutic potential

Nature (London), 2021-01, Vol.589 (7842), p.474-479

2021

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Identification of Psychoplastogenic N,N‑Dimethylaminoisotryptamine (isoDMT) Analogues through Structure–Activity Relationship Studies

Journal of medicinal chemistry, 2020-02, Vol.63 (3), p.1142-1155

2020

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Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds

Nature chemical biology, 2016-07, Vol.12 (7), p.559-566

2016

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cables1 is required for embryonic neural development: molecular, cellular, and behavioral evidence from the zebrafish

Molecular reproduction and development, 2011-01, Vol.78 (1), p.22-32

2011

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Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish

Frontiers in pharmacology, 2014-07, Vol.5, p.153-153

2014

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Using the Zebrafish Photomotor Response for Psychotropic Drug Screening

Methods in Cell Biology, 2011, Vol.105, p.517-524

2011

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Live imaging of apoptotic cells in zebrafish

The FASEB journal, 2010-11, Vol.24 (11), p.4336-4342

2010

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Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent of ced-9

Molecular cell, 2008-08, Vol.31 (4), p.586-597

2008

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Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans

Nature, 2005-10, Vol.437 (7060), p.831-837

2005

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Photochemical activation of TRPA1 channels in neurons and animals

Nature chemical biology, 2013-04, Vol.9 (4), p.257-263

2013

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A Multimodal, In Vivo Approach for Assessing Structurally and Phenotypically Related Neuroactive Molecules

ACS chemical neuroscience, 2024-09

2024

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Apoptotic Cells Are Cleared by Directional Migration and elmo1- Dependent Macrophage Engulfment

Current biology, 2012-05, Vol.22 (9), p.830-836

2012

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Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology

Trends in biotechnology (Regular ed.), 2012-08, Vol.30 (8), p.421-425

2012

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Class of Benzenoid Chemicals Suppresses Apoptosis in C. elegans

Chembiochem : a European journal of chemical biology, 2006-12, Vol.7 (12), p.2010-2015

2006

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σ1 receptor ligands control a switch between passive and active threat responses

Nature chemical biology, 2016-07, Vol.12 (7), p.552-558

2016

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Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4

Molecular cell, 2004-09, Vol.15 (6), p.999-1006

2004

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An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action

Journal of biomolecular screening, 2013-01, Vol.18 (1), p.108-115

2013

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Zebrafish Behavioral Profiling Links Drugs to Biological Targets and Rest/Wake Regulation

Rapid behavior-based identification of neuroactive small molecules in the zebrafish

Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

Zebrafish behavioural profiling identifies GABA and serotonin receptor ligands related to sedation and paradoxical excitation

Identification of nonvisual photomotor response cells in the vertebrate hindbrain

Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology

Chemical informatics and target identification in a zebrafish phenotypic screen

The nongenotoxic carcinogens naphthalene and para -dichlorobenzene suppress apoptosis in Caenorhabditis elegans

A non-hallucinogenic psychedelic analogue with therapeutic potential

Identification of Psychoplastogenic N,N‑Dimethylaminoisotryptamine (isoDMT) Analogues through Structure–Activity Relationship Studies

Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds

cables1 is required for embryonic neural development: molecular, cellular, and behavioral evidence from the zebrafish

Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish

Using the Zebrafish Photomotor Response for Psychotropic Drug Screening

Live imaging of apoptotic cells in zebrafish

Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent of ced-9

Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans

Photochemical activation of TRPA1 channels in neurons and animals

A Multimodal, In Vivo Approach for Assessing Structurally and Phenotypically Related Neuroactive Molecules

Apoptotic Cells Are Cleared by Directional Migration and elmo1- Dependent Macrophage Engulfment

Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology

Class of Benzenoid Chemicals Suppresses Apoptosis in C. elegans

σ1 receptor ligands control a switch between passive and active threat responses

Structural, Biochemical, and Functional Analyses of CED-9 Recognition by the Proapoptotic Proteins EGL-1 and CED-4

An in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of action

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