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Glucose-Sensing Receptor in Pancreatic Beta-cells

Kojima, Itaru

1, 2019

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Transient receptor potential vanilloid 2 activation by focal mechanical stimulation requires interaction with the actin cytoskeleton and enhances growth cone motility

The FASEB journal, 2017-04, Vol.31 (4), p.1368-1381

2017

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Prolonged Insulin Stimulation Down-regulates GLUT4 through Oxidative Stress-mediated Retromer Inhibition by a Protein Kinase CK2-dependent Mechanism in 3T3-L1 Adipocytes

The Journal of biological chemistry, 2014-01, Vol.289 (1), p.133-142

2014

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Role of the glucose‐sensing receptor in insulin secretion

Diabetes, obesity & metabolism, 2017-09, Vol.19 (S1), p.54-62

2017

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Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3

Endocrine Journal, 2014, Vol.61(2), pp.119-131

2014

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Glucose Evokes Rapid Ca2+ and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells

PloS one, 2015-12, Vol.10 (12), p.e0144053-e0144053

2015

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Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

PloS one, 2009-04, Vol.4 (4), p.e5106-e5106

2009

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Translocation of calcium-permeable TRPV2 channel to the podosome: Its role in the regulation of podosome assembly

Cell calcium (Edinburgh), 2012-02, Vol.51 (2), p.186-193

2012

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A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells

PloS one, 2013-01, Vol.8 (1), p.e54500-e54500

2013

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Sweet Taste Receptor Serves to Activate Glucose- and Leptin-Responsive Neurons in the Hypothalamic Arcuate Nucleus and Participates in Glucose Responsiveness

Frontiers in neuroscience, 2016-11, Vol.10, p.502-502

2016

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Chemotactic peptide fMetLeuPhe induces translocation of the TRPV2 channel in macrophages

Journal of cellular physiology, 2007-03, Vol.210 (3), p.692-702

2007

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Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms

Endocrine Journal, 2016, Vol.63(8), pp.715-725

2016

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Expression of the glucose-sensing receptor T1R3 in pancreatic islet: changes in the expression levels in various nutritional and metabolic states

Endocrine Journal, 2014, Vol.61(8), pp.797-805

2014

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Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose

The Journal of biological chemistry, 2016-10, Vol.291 (44), p.23126-23135

2016

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Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice

Endocrinology (Philadelphia), 2016-05, Vol.157 (5), p.1839-1851

2016

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Arabidopsis plasma membrane protein crucial for Ca²⁺ influx and touch sensing in roots

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (9), p.3639-3644

2007

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Regulation of Calcium-Permeable TRPV2 Channel by Insulin in Pancreatic β-Cells

Diabetes (New York, N.Y.), 2009-01, Vol.58 (1), p.174-184

2009

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Translocation of TRPV2 channel induced by focal administration of mechanical stress

Physiological reports, 2015-02, Vol.3 (2), p.e12296-n/a

2015

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The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic β-Cells

Diabetes and Metabolism Journal, 2011, 35(5), 127, pp.451-457

2011

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T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells

PloS one, 2017-05, Vol.12 (5), p.e0176841-e0176841

2017

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Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists

Endocrine Journal, 2013, Vol.60(10), pp.1191-1206

2013

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Role of small proliferative adipocytes: possible beige cell progenitors

Journal of endocrinology, 2020-04, Vol.245 (1), p.65-78

2020

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Glucose-Sensing Receptor T1R3: A New Signaling Receptor Activated by Glucose in Pancreatic β-Cells

Biological and Pharmaceutical Bulletin, 2015/05/01, Vol.38(5), pp.674-679

2015

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Conophylline Suppresses Pancreatic Stellate Cells and Improves Islet Fibrosis in Goto-Kakizaki Rats

Endocrinology (Philadelphia), 2012-02, Vol.153 (2), p.621-630

2012

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Sweet Taste-Sensing Receptors Expressed in Pancreatic β-Cells: Sweet Molecules Act as Biased Agonists

Endocrinology and metabolism (Seoul), 2014-03, Vol.29 (1), p.12-19

2014

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Glucose-Sensing Receptor in Pancreatic Beta-cells

Transient receptor potential vanilloid 2 activation by focal mechanical stimulation requires interaction with the actin cytoskeleton and enhances growth cone motility

Prolonged Insulin Stimulation Down-regulates GLUT4 through Oxidative Stress-mediated Retromer Inhibition by a Protein Kinase CK2-dependent Mechanism in 3T3-L1 Adipocytes

Role of the glucose‐sensing receptor in insulin secretion

Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3

Glucose Evokes Rapid Ca2+ and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells

Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

Translocation of calcium-permeable TRPV2 channel to the podosome: Its role in the regulation of podosome assembly

A novel regulatory function of sweet taste-sensing receptor in adipogenic differentiation of 3T3-L1 cells

Sweet Taste Receptor Serves to Activate Glucose- and Leptin-Responsive Neurons in the Hypothalamic Arcuate Nucleus and Participates in Glucose Responsiveness

Chemotactic peptide fMetLeuPhe induces translocation of the TRPV2 channel in macrophages

Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms

Expression of the glucose-sensing receptor T1R3 in pancreatic islet: changes in the expression levels in various nutritional and metabolic states

Positive Allosteric Modulation of the Calcium-sensing Receptor by Physiological Concentrations of Glucose

Blockade of Sphingosine 1-Phosphate Receptor 2 Signaling Attenuates High-Fat Diet-Induced Adipocyte Hypertrophy and Systemic Glucose Intolerance in Mice

Arabidopsis plasma membrane protein crucial for Ca²⁺ influx and touch sensing in roots

Regulation of Calcium-Permeable TRPV2 Channel by Insulin in Pancreatic β-Cells

Translocation of TRPV2 channel induced by focal administration of mechanical stress

The Role of the Sweet Taste Receptor in Enteroendocrine Cells and Pancreatic β-Cells

T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells

Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists

Role of small proliferative adipocytes: possible beige cell progenitors

Glucose-Sensing Receptor T1R3: A New Signaling Receptor Activated by Glucose in Pancreatic β-Cells

Conophylline Suppresses Pancreatic Stellate Cells and Improves Islet Fibrosis in Goto-Kakizaki Rats

Sweet Taste-Sensing Receptors Expressed in Pancreatic β-Cells: Sweet Molecules Act as Biased Agonists

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