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Cardiomyocytes: Analysis of Temperature Response and Signal Propagation Between Dissociated Clusters Using Novel Video-Based Movement Analysis Software

IEEE access, 2020, Vol.8, p.109275-109288

2020

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Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study

PLoS computational biology, 2011-01, Vol.7 (1), p.e1001067-e1001067

2011

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Calcium signalling in developing cardiomyocytes: implications for model systems and disease

The Journal of physiology, 2015-03, Vol.593 (5), p.1047-1063

2015

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In silico screening of the key cellular remodeling targets in chronic atrial fibrillation

PLoS computational biology, 2014-05, Vol.10 (5), p.e1003620-e1003620

2014

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In silico study of the mechanisms of hypoxia and contractile dysfunction during ischemia and reperfusion of hiPSC cardiomyocytes

Disease models & mechanisms, 2024-04, Vol.17 (4)

2024

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Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling

Frontiers in physiology, 2018-02, Vol.9, p.80-80

2018

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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

EMBO molecular medicine, 2019-12, Vol.11 (12), p.e11115-n/a

2019

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Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges

Frontiers in physiology, 2018-09, Vol.9, p.1221-1221

2018

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Benchmarking electrophysiological models of human atrial myocytes

Frontiers in physiology, 2013-01, Vol.3, p.487-487

2013

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Computational cardiac physiology for new modelers: Origins, foundations, and future

Acta Physiologica, 2022-10, Vol.236 (2), p.e13865-n/a

2022

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Translational investigation of electrophysiology in hypertrophic cardiomyopathy

Journal of molecular and cellular cardiology, 2021-08, Vol.157, p.77-89

2021

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Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective

Frontiers in physiology, 2023-02, Vol.14, p.1132165-1132165

2023

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Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions

Frontiers in pharmacology, 2021-03, Vol.12, p.604713-604713

2021

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Refractoriness in human atria: Time and voltage dependence of sodium channel availability

Journal of molecular and cellular cardiology, 2016-12, Vol.101, p.26-34

2016

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Human Induced Pluripotent Stem Cell–Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers

Circulation. Arrhythmia and electrophysiology, 2018-07, Vol.11 (7), p.e006035-e006035

2018

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Building blocks of microphysiological system to model physiology and pathophysiology of human heart

Frontiers in physiology, 2023-07, Vol.14, p.1213959-1213959

2023

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A mathematical model of hiPSC cardiomyocytes electromechanics

Physiological reports, 2021-11, Vol.9 (22), p.e15124-n/a

2021

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Altered contractility in mutation-specific hypertrophic cardiomyopathy: A mechano-energetic in silico study with pharmacological insights

Frontiers in physiology, 2022-10, Vol.13, p.1010786-1010786

2022

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Cardiac cell modelling: Observations from the heart of the cardiac physiome project

Progress in biophysics and molecular biology, 2011, Vol.104 (1), p.2-21

2011

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Prolonged action potentials in HCM-derived iPSC--biology or artefact?

Cardiovascular research, 2015-04, Vol.106 (1), p.6-6

2015

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hiPSC-Derived Cardiomyocyte Model of LQT2 Syndrome Derived from Asymptomatic and Symptomatic Mutation Carriers Reproduces Clinical Differences in Aggregates but Not in Single Cells

Cells (Basel, Switzerland), 2020-05, Vol.9 (5), p.1153

2020

Volltextzugriff (PDF)

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart

Frontiers in physiology, 2017-05, Vol.8, p.373-373

2017

Volltextzugriff (PDF)

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

EMBO molecular medicine, 2022-08, Vol.14 (8), p.e16423-n/a

2022

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Local Ca2+ releases enable rapid heart rates in developing cardiomyocytes

The Journal of physiology, 2010-05, Vol.588 (9), p.1407-1417

2010

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Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

American journal of physiology. Heart and circulatory physiology, 2015-08, Vol.309 (3), p.H481-H489

2015

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Cardiomyocytes: Analysis of Temperature Response and Signal Propagation Between Dissociated Clusters Using Novel Video-Based Movement Analysis Software

Impact of sarcoplasmic reticulum calcium release on calcium dynamics and action potential morphology in human atrial myocytes: a computational study

Calcium signalling in developing cardiomyocytes: implications for model systems and disease

In silico screening of the key cellular remodeling targets in chronic atrial fibrillation

In silico study of the mechanisms of hypoxia and contractile dysfunction during ischemia and reperfusion of hiPSC cardiomyocytes

Structural Immaturity of Human iPSC-Derived Cardiomyocytes: In Silico Investigation of Effects on Function and Disease Modeling

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

Computational Modeling of Electrophysiology and Pharmacotherapy of Atrial Fibrillation: Recent Advances and Future Challenges

Benchmarking electrophysiological models of human atrial myocytes

Computational cardiac physiology for new modelers: Origins, foundations, and future

Translational investigation of electrophysiology in hypertrophic cardiomyopathy

Human induced pluripotent stem cell-derived cardiomyocytes as an electrophysiological model: Opportunities and challenges-The Hamburg perspective

Comparison of the Simulated Response of Three in Silico Human Stem Cell-Derived Cardiomyocytes Models and in Vitro Data Under 15 Drug Actions

Refractoriness in human atria: Time and voltage dependence of sodium channel availability

Human Induced Pluripotent Stem Cell–Derived Engineered Heart Tissue as a Sensitive Test System for QT Prolongation and Arrhythmic Triggers

Building blocks of microphysiological system to model physiology and pathophysiology of human heart

A mathematical model of hiPSC cardiomyocytes electromechanics

Altered contractility in mutation-specific hypertrophic cardiomyopathy: A mechano-energetic in silico study with pharmacological insights

Cardiac cell modelling: Observations from the heart of the cardiac physiome project

Prolonged action potentials in HCM-derived iPSC--biology or artefact?

hiPSC-Derived Cardiomyocyte Model of LQT2 Syndrome Derived from Asymptomatic and Symptomatic Mutation Carriers Reproduces Clinical Differences in Aggregates but Not in Single Cells

Vascular Endothelial Growth Factor-B Induces a Distinct Electrophysiological Phenotype in Mouse Heart

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

Local Ca2+ releases enable rapid heart rates in developing cardiomyocytes

Preservation of cardiac function by prolonged action potentials in mice deficient of KChIP2

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