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Structural and Biological Properties of the Drosophila Insulin-like Peptide 5 Show Evolutionary Conservation

The Journal of biological chemistry, 2011-01, Vol.286 (1), p.661-673

2011

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Balanced Regulation of Proliferation, Growth, Differentiation, and Degradation in Skeletal Cells

Annals of the New York Academy of Sciences, 2007-11, Vol.1116 (1), p.165-173

2007

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Advances in Geroscience: Impact on Healthspan and Chronic Disease

The journals of gerontology. Series A, Biological sciences and medical sciences, 2014-06, Vol.69 (Suppl_1), p.S1-S3

2014

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The Intersection of Aging Biology and the Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop

The journals of gerontology. Series A, Biological sciences and medical sciences, 2017-11, Vol.72 (11), p.1492-1500

2017

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Reverse geroscience: how does exposure to early diseases accelerate the age-related decline in health?

Annals of the New York Academy of Sciences, 2016-12, Vol.1386 (1), p.30-44

2016

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Stat5 is a Physiological Substrate of the Insulin Receptor

Proceedings of the National Academy of Sciences - PNAS, 1997-03, Vol.94 (6), p.2295-2300

1997

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Advances in Geroscience

1st ed. 2016, 2015

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A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo

Diabetes (New York, N.Y.), 2001-04, Vol.50 (4), p.824-830

2001

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Mechanism-based design of a protein kinase inhibitor

Nature structural & molecular biology, 2001-01, Vol.8 (1), p.37-41

2001

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Axons Guided by Insulin Receptor in Drosophila Visual System

Science (American Association for the Advancement of Science), 2003-04, Vol.300 (5618), p.502-505

2003

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Dual Mechanism of Signal Transducer and Activator of Transcription 5 Activation by the Insulin Receptor

Molecular endocrinology (Baltimore, Md.), 2002-12, Vol.16 (12), p.2764-2779

2002

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Regulation of mOAT-mediated Organic Anion Transport by Okadaic Acid and Protein Kinase C in LLC-PK1 Cells

The Journal of biological chemistry, 2000-04, Vol.275 (14), p.10278-10284

2000

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Activation of the Insulin Receptor's Kinase Domain Changes the Rate-Determining Step of Substrate Phosphorylation

Biochemistry (Easton), 2001-01, Vol.40 (2), p.504-513

2001

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The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase

Nucleic acids research, 1999-10, Vol.27 (20), p.4106

1999

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Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: Molecular yardsticks for analyzing catalytic mechanism and inhibitor design

Bioorganic chemistry, 2005-08, Vol.33 (4), p.285-297

2005

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Multiple Activation Loop Conformations and Their Regulatory Properties in the Insulin Receptor's Kinase Domain

The Journal of biological chemistry, 2001-12, Vol.276 (50), p.46933-46940

2001

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Probing the Catalytic Mechanism of the Insulin Receptor Kinase with a Tetrafluorotyrosine-containing Peptide Substrate

The Journal of biological chemistry, 2000-09, Vol.275 (39), p.30394-30398

2000

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Purification, Identification, and Properties of a Saccharomyces cerevisiae Oleate-activated Upstream Activating Sequence-binding Protein That Is Involved in the Activation of POX1(∗)

The Journal of biological chemistry, 1996-05, Vol.271 (20), p.12068-12075

1996

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Lysozyme Degradation by the Bovine Multicatalytic Proteinase Complex (Proteasome): Evidence for a Nonprocessive Mode of Degradation

Biochemistry (Easton), 1999-11, Vol.38 (44), p.14573-14581

1999

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Cis-Autophosphorylation of Juxtamembrane Tyrosines in the Insulin Receptor Kinase Domain

Biochemistry (Easton), 1997-06, Vol.36 (25), p.7681-7689

1997

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Autophosphorylation Dependent Destabilization of the Insulin Receptor Kinase Domain: Tryptophan-1175 Reports Changes in the Catalytic Cleft

Biochemistry (Easton), 1999-03, Vol.38 (10), p.3079-3089

1999

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A Binding Site for Multiple Transcriptional Activators in the fushi tarazu Proximal Enhancer Is Essential for Gene Expression In Vivo

Molecular and Cellular Biology, 1998-06, Vol.18 (6), p.3384-3394

1998

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Conformational changes in the activation loop of the insulin receptor's kinase domain

Protein science, 1999-10, Vol.8 (10), p.2158-2165

1999

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Intrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor

Molecular and Cellular Biology, 2001-07, Vol.21 (13), p.4197-4207

2001

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Partial Activation of the Insulin Receptor Kinase Domain by Juxtamembrane Autophosphorylation

Biochemistry (Easton), 1998-08, Vol.37 (32), p.11289-11300

1998

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Structural and Biological Properties of the Drosophila Insulin-like Peptide 5 Show Evolutionary Conservation

Balanced Regulation of Proliferation, Growth, Differentiation, and Degradation in Skeletal Cells

Advances in Geroscience: Impact on Healthspan and Chronic Disease

The Intersection of Aging Biology and the Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop

Reverse geroscience: how does exposure to early diseases accelerate the age-related decline in health?

Stat5 is a Physiological Substrate of the Insulin Receptor

Advances in Geroscience

A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo

Mechanism-based design of a protein kinase inhibitor

Axons Guided by Insulin Receptor in Drosophila Visual System

Dual Mechanism of Signal Transducer and Activator of Transcription 5 Activation by the Insulin Receptor

Regulation of mOAT-mediated Organic Anion Transport by Okadaic Acid and Protein Kinase C in LLC-PK1 Cells

Activation of the Insulin Receptor's Kinase Domain Changes the Rate-Determining Step of Substrate Phosphorylation

The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase

Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: Molecular yardsticks for analyzing catalytic mechanism and inhibitor design

Multiple Activation Loop Conformations and Their Regulatory Properties in the Insulin Receptor's Kinase Domain

Probing the Catalytic Mechanism of the Insulin Receptor Kinase with a Tetrafluorotyrosine-containing Peptide Substrate

Purification, Identification, and Properties of a Saccharomyces cerevisiae Oleate-activated Upstream Activating Sequence-binding Protein That Is Involved in the Activation of POX1(∗)

Lysozyme Degradation by the Bovine Multicatalytic Proteinase Complex (Proteasome): Evidence for a Nonprocessive Mode of Degradation

Cis-Autophosphorylation of Juxtamembrane Tyrosines in the Insulin Receptor Kinase Domain

Autophosphorylation Dependent Destabilization of the Insulin Receptor Kinase Domain: Tryptophan-1175 Reports Changes in the Catalytic Cleft

A Binding Site for Multiple Transcriptional Activators in the fushi tarazu Proximal Enhancer Is Essential for Gene Expression In Vivo

Conformational changes in the activation loop of the insulin receptor's kinase domain

Intrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor

Partial Activation of the Insulin Receptor Kinase Domain by Juxtamembrane Autophosphorylation

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