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Activation of the Insulin Receptor's Kinase Domain Changes the Rate-Determining Step of Substrate Phosphorylation

Biochemistry (Easton), 2001-01, Vol.40 (2), p.504-513

2001

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Mechanism-based design of a protein kinase inhibitor

Nature structural & molecular biology, 2001-01, Vol.8 (1), p.37-41

2001

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Axons Guided by Insulin Receptor in Drosophila Visual System

Science (American Association for the Advancement of Science), 2003-04, Vol.300 (5618), p.502-505

2003

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Insulin receptor autophosphorylation. II. Determination of autophosphorylation sites by chemical sequence analysis and identification of the juxtamembrane sites

Biochemistry (Easton), 1993-06, Vol.32 (22), p.5773-5780

Kohanski, R. A

1993

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Insulin receptor autophosphorylation. I. Autophosphorylation kinetics of the native receptor and its cytoplasmic kinase domain

Biochemistry (Easton), 1993-06, Vol.32 (22), p.5766-5772

Kohanski, R. A

1993

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Advances in Geroscience: Impact on Healthspan and Chronic Disease

The journals of gerontology. Series A, Biological sciences and medical sciences, 2014-06, Vol.69 (Suppl_1), p.S1-S3

2014

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Insulin Receptor Aggregation and Autophosphorylation in the Presence of Cationic Polyamino Acids

The Journal of biological chemistry, 1989-12, Vol.264 (35), p.20984-20991

Kohanski, R A

1989

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Conformational changes in the activation loop of the insulin receptor's kinase domain

Protein science, 1999-10, Vol.8 (10), p.2158-2165

1999

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Intrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor

Molecular and Cellular Biology, 2001-07, Vol.21 (13), p.4197-4207

2001

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Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression

Molecular and Cellular Biology, 1995-12, Vol.15 (12), p.6813-6819

1995

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Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity

The Journal of biological chemistry, 1997-05, Vol.272 (18), p.11824-11831

1997

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Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes

The Journal of biological chemistry, 1984-04, Vol.259 (7), p.4566-4575

1984

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Altered properties of the branched chain amino acid-preferring activity contribute to increased cleavages after branched chain residues by the "immunoproteasome"

The Journal of biological chemistry, 1998-07, Vol.273 (27), p.16764-16770

1998

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Effect of phenylarsine oxide on insulin-dependent protein phosphorylation and glucose transport in 3T3-L1 adipocytes

The Journal of biological chemistry, 1987-07, Vol.262 (20), p.9872-9876

1987

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Phenylarsine Oxide Inhibits Insulin Activation of Phosphatidylinositol 3′-Kinase

Biochemical and biophysical research communications, 1997-10, Vol.239 (1), p.316-321

1997

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Stat5 is a Physiological Substrate of the Insulin Receptor

Proceedings of the National Academy of Sciences - PNAS, 1997-03, Vol.94 (6), p.2295-2300

1997

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Insulin-dependent phosphorylation of the insulin receptor-protein kinase and activation of glucose transport in 3T3-L1 adipocytes

The Journal of biological chemistry, 1986-09, Vol.261 (26), p.12272-12281

1986

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Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism

The Journal of biological chemistry, 2001-03, Vol.276 (13), p.10049-10055

2001

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A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo

Diabetes (New York, N.Y.), 2001-04, Vol.50 (4), p.824-830

2001

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[20] Monovalent avidin affinity columns

Methods in Enzymology, 1990, Vol.184, p.194-200

1990

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NIA HEALTH DISPARITIES RESEARCH NETWORK: APPROACHES AND FINDINGS FROM AGING BIOLOGY RESEARCH

Innovation in aging, 2018-11, Vol.2 (suppl_1), p.768-768

2018

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Control of insulin receptor autophosphorylation by polypeptide substrates. Inhibition and stimulation by interaction with the catalytic subunit

Biochemistry (Easton), 1991-03, Vol.30 (9), p.2406-2414

1991

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The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase

Nucleic acids research, 1999-10, Vol.27 (20), p.4106-4113

1999

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Homogeneous functional insulin receptor from 3T3-L1 adipocytes. Purification using N alpha B1-(biotinyl-epsilon-aminocaproyl)insulin and avidin-sepharose

The Journal of biological chemistry, 1985-04, Vol.260 (8), p.5014-5025

1985

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Multiple Activation Loop Conformations and Their Regulatory Properties in the Insulin Receptor's Kinase Domain

The Journal of biological chemistry, 2001-12, Vol.276 (50), p.46933-46940

2001

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Activation of the Insulin Receptor's Kinase Domain Changes the Rate-Determining Step of Substrate Phosphorylation

Mechanism-based design of a protein kinase inhibitor

Axons Guided by Insulin Receptor in Drosophila Visual System

Insulin receptor autophosphorylation. II. Determination of autophosphorylation sites by chemical sequence analysis and identification of the juxtamembrane sites

Insulin receptor autophosphorylation. I. Autophosphorylation kinetics of the native receptor and its cytoplasmic kinase domain

Advances in Geroscience: Impact on Healthspan and Chronic Disease

Insulin Receptor Aggregation and Autophosphorylation in the Presence of Cationic Polyamino Acids

Conformational changes in the activation loop of the insulin receptor's kinase domain

Intrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor

Tyrosine dephosphorylation of nuclear proteins mimics transforming growth factor beta 1 stimulation of alpha 2(I) collagen gene expression

Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity

Role of glycosylation in the processing of newly translated insulin proreceptor in 3T3-L1 adipocytes

Altered properties of the branched chain amino acid-preferring activity contribute to increased cleavages after branched chain residues by the "immunoproteasome"

Effect of phenylarsine oxide on insulin-dependent protein phosphorylation and glucose transport in 3T3-L1 adipocytes

Phenylarsine Oxide Inhibits Insulin Activation of Phosphatidylinositol 3′-Kinase

Stat5 is a Physiological Substrate of the Insulin Receptor

Insulin-dependent phosphorylation of the insulin receptor-protein kinase and activation of glucose transport in 3T3-L1 adipocytes

Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: insights into kinase mechanism

A Novel Small Molecule That Directly Sensitizes the Insulin Receptor In Vitro and In Vivo

[20] Monovalent avidin affinity columns

NIA HEALTH DISPARITIES RESEARCH NETWORK: APPROACHES AND FINDINGS FROM AGING BIOLOGY RESEARCH

Control of insulin receptor autophosphorylation by polypeptide substrates. Inhibition and stimulation by interaction with the catalytic subunit

The promyelocytic leukemia zinc finger (PLZF) protein binds DNA in a high molecular weight complex associated with cdc2 kinase

Homogeneous functional insulin receptor from 3T3-L1 adipocytes. Purification using N alpha B1-(biotinyl-epsilon-aminocaproyl)insulin and avidin-sepharose

Multiple Activation Loop Conformations and Their Regulatory Properties in the Insulin Receptor's Kinase Domain

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