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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4485-4500

2018

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Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation

Circulation research, 2019-09, Vol.125 (7), p.662-677

2019

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Cortical bone stem cell-derived exosomes' therapeutic effect on myocardial ischemia-reperfusion and cardiac remodeling

American journal of physiology. Heart and circulatory physiology, 2021-12, Vol.321 (6), p.H1014-H1029

2021

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Cortical bone stem cells modify cardiac inflammation after myocardial infarction by inducing a novel macrophage phenotype

American journal of physiology. Heart and circulatory physiology, 2021-10, Vol.321 (4), p.H684-H701

2021

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High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling

Arteriosclerosis, thrombosis, and vascular biology, 2020-08, Vol.40 (8), p.1854-1869

2020

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Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart

Circulation research, 2023-01, Vol.132 (1), p.10-29

2023

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p38α: A Profibrotic Signaling Nexus

Circulation (New York, N.Y.), 2017-08, Vol.136 (6), p.562-565

2017

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A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

FEBS letters, 2010-02, Vol.584 (3), p.631-637

2010

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The potential of targeting epigenetic regulators for the treatment of fibrotic cardiac diseases

Future medicinal chemistry, 2016-09, Vol.8 (13), p.1533-1536

2016

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Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5422-5438

2010

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3,5-Diarylazoles as novel and selective inhibitors of protein kinase D

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (5), p.1447-1451

2011

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Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1

Biochimica et biophysica acta, 2009-05, Vol.1789 (5), p.422-431

2009

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Screening and identification of a novel class of TGF-β type 1 receptor kinase inhibitor

Journal of biomolecular screening, 2011-08, Vol.16 (7), p.724-733

2011

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p38α: a pro-fibrotic signaling nexus

Circulation (New York, N.Y.), 2017-08, Vol.136 (6), p.562-565

2017

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Phenotypic screening uncovers eicosanoid degradation in fibroblasts as a therapeutic target for cardiac fibrosis

Journal of molecular and cellular cardiology, 2022-12, Vol.173, p.39-39

2022

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Abstract 428: Cortical Bone Stem Cell-derived Exosomes Reduce Myofibroblast Activation in Rat and Human Cardiac Fibroblasts

Circulation research, 2020-07, Vol.127 (Suppl_1)

2020

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Dynamic Regulation of Copper Uptake and Detoxification Genes in Saccharomyces cerevisiae

Molecular and Cellular Biology, 1998-05, Vol.18 (5), p.2514-2523

1998

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Sphingolipid biosynthesis in pathogenic fungi: Identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus

Biochimica et biophysica acta, 2006, Vol.1761 (1), p.52-63

2006

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The role of Midkine in Children with Dilated Cardiomyopathy

Journal of molecular and cellular cardiology, 2017-11, Vol.112, p.143-144

2017

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The role of the conserved Lys68:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: Multiple forced covariant amino acid substitutions in natural variants

Protein science, 2002-05, Vol.11 (5), p.1062-1073

2002

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A trans-Activation Domain in Yeast Heat Shock Transcription Factor Is Essential for Cell Cycle Progression during Stress

Molecular and Cellular Biology, 1999-01, Vol.19 (1), p.402-411

1999

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Abstract PO3-26-02: Identification of a novel, brain penetrant, EGFR sparing, ErbB2 inhibitor with activity against oncogenic ErbB2 mutations

Cancer research (Chicago, Ill.), 2024-05, Vol.84 (9_Supplement), p.PO3-26-02-PO3-26-02

2024

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Abstract PO3-26-01: Preclinical in vitro and in vivo characterization of a novel, wild-type-sparing, PI3Kα H1047R mutant-selective inhibitor

Cancer research (Chicago, Ill.), 2024-05, Vol.84 (9_Supplement), p.PO3-26-01-PO3-26-01

2024

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4485-4500

2018

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Abstract C161: Identification of a reversible selective FGFR2 clinical development candidate with potency against gatekeeper and molecular brake mutations

Molecular cancer therapeutics, 2023-12, Vol.22 (12_Supplement), p.C161-C161

2023

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ASK1 contributes to fibrosis and dysfunction in models of kidney disease

Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation

Cortical bone stem cell-derived exosomes' therapeutic effect on myocardial ischemia-reperfusion and cardiac remodeling

Cortical bone stem cells modify cardiac inflammation after myocardial infarction by inducing a novel macrophage phenotype

High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling

Inhibition of Eicosanoid Degradation Mitigates Fibrosis of the Heart

p38α: A Profibrotic Signaling Nexus

A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase

The potential of targeting epigenetic regulators for the treatment of fibrotic cardiac diseases

Identification of Potent and Selective Amidobipyridyl Inhibitors of Protein Kinase D

3,5-Diarylazoles as novel and selective inhibitors of protein kinase D

Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1

Screening and identification of a novel class of TGF-β type 1 receptor kinase inhibitor

p38α: a pro-fibrotic signaling nexus

Phenotypic screening uncovers eicosanoid degradation in fibroblasts as a therapeutic target for cardiac fibrosis

Abstract 428: Cortical Bone Stem Cell-derived Exosomes Reduce Myofibroblast Activation in Rat and Human Cardiac Fibroblasts

Dynamic Regulation of Copper Uptake and Detoxification Genes in Saccharomyces cerevisiae

Sphingolipid biosynthesis in pathogenic fungi: Identification and characterization of the 3-ketosphinganine reductase activity of Candida albicans and Aspergillus fumigatus

The role of Midkine in Children with Dilated Cardiomyopathy

The role of the conserved Lys68:Glu265 intersubunit salt bridge in aspartate aminotransferase kinetics: Multiple forced covariant amino acid substitutions in natural variants

A trans-Activation Domain in Yeast Heat Shock Transcription Factor Is Essential for Cell Cycle Progression during Stress

Abstract PO3-26-02: Identification of a novel, brain penetrant, EGFR sparing, ErbB2 inhibitor with activity against oncogenic ErbB2 mutations

Abstract PO3-26-01: Preclinical in vitro and in vivo characterization of a novel, wild-type-sparing, PI3Kα H1047R mutant-selective inhibitor

ASK1 contributes to fibrosis and dysfunction in models of kidney disease

Abstract C161: Identification of a reversible selective FGFR2 clinical development candidate with potency against gatekeeper and molecular brake mutations

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