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Non-peptide orexin 2 receptor modulators as promising way to treatment of narcolepsy/insomnia

Journal of the neurological sciences, 2019-10, Vol.405, p.98-98

2019

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Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation

ACS chemical biology, 2023-09, Vol.18 (9), p.1993-2002

2023

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Discovery of a 6‑Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities

ACS pharmacology & translational science, 2024-09, Vol.7 (9), p.2755-2783

2024

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The incidence and outcomes of acute coronary syndromes in a central European country: Results of the CZECH-2 registry

International journal of cardiology, 2014-05, Vol.173 (2), p.204-208

2014

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Effect of P-glycoprotein on the availability of oxime reactivators in the brain

Toxicology (Amsterdam), 2020-10, Vol.443, p.152541, Article 152541

2020

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Current approaches to enhancing oxime reactivator delivery into the brain

Toxicology (Amsterdam), 2019-07, Vol.423, p.75-83

2019

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Neurotoxicity evoked by organophosphates and available countermeasures

Archives of toxicology, 2023, Vol.97 (1), p.39-72

2023

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Orexin supplementation in narcolepsy treatment: A review

Medicinal research reviews, 2019-05, Vol.39 (3), p.961-975

2019

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Novel application of capillary electrophoresis with a liposome coated capillary for prediction of blood-brain barrier permeability

Talanta (Oxford), 2020-09, Vol.217, p.121023-121023, Article 121023

2020

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Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity

Archives of toxicology, 2023-08, Vol.97 (8), p.2209-2217

2023

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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase

Archives of toxicology, 2021-03, Vol.95 (3), p.985-1001

2021

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Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile

European journal of medicinal chemistry, 2020-10, Vol.203, p.112593, Article 112593

2020

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Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer’s Disease

Current Alzheimer research, 2019-01, Vol.16 (9), p.821-833

2019

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Plant functional groups and phylogenetic regularity control plant community bioelement composition through calcium and magnesium

Oikos, 2023-04, Vol.2023 (4), p.n/a

2023

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2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer’s disease

European journal of medicinal chemistry, 2021-02, Vol.211, p.113112, Article 113112

2021

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Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors

Biomolecules (Basel, Switzerland), 2019-08, Vol.9 (8), p.379

2019

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Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods

Molecules (Basel, Switzerland), 2018-11, Vol.23 (11), p.2926

2018

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Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication

Chemico-biological interactions, 2024-05, Vol.394, p.110941-110941, Article 110941

2024

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Stoichiometry versus ecology: the relationships between genome size and guanine-cytosine content, and tissue nitrogen and phosphorus in grassland herbs

Annals of botany, 2022-09, Vol.130 (2), p.189-197

2022

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New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

Journal of medicinal chemistry, 2019-12, Vol.62 (24), p.11416-11422

2019

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7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties

European journal of medicinal chemistry, 2022-10, Vol.240, p.114580-114580, Article 114580

2022

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Disentangling the taxonomic structure of the Allium paniculatum species complex in central and eastern Europe using molecular, cytogenetic and morphological tools

Preslia (Praha), 2023-01, Vol.95 (1), p.119-163

2023

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First insight into the genomes of the Pulmonaria officinalis group (Boraginaceae) provided by repeatome analysis and comparative karyotyping

BMC plant biology, 2024-09, Vol.24 (1), p.859-17, Article 859

2024

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Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects

European journal of medicinal chemistry, 2024-10, Vol.280, p.116981, Article 116981

2024

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First insights into the evolution of genome size in the borage family: a complete data set for Boraginaceae from the Czech Republic

Botanical journal of the Linnean Society, 2019-01, Vol.189 (2), p.115-131

2019

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Non-peptide orexin 2 receptor modulators as promising way to treatment of narcolepsy/insomnia

Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation

Discovery of a 6‑Aminobenzo[b]thiophene 1,1-Dioxide Derivative (K2071) with a Signal Transducer and Activator of Transcription 3 Inhibitory, Antimitotic, and Senotherapeutic Activities

The incidence and outcomes of acute coronary syndromes in a central European country: Results of the CZECH-2 registry

Effect of P-glycoprotein on the availability of oxime reactivators in the brain

Current approaches to enhancing oxime reactivator delivery into the brain

Neurotoxicity evoked by organophosphates and available countermeasures

Orexin supplementation in narcolepsy treatment: A review

Novel application of capillary electrophoresis with a liposome coated capillary for prediction of blood-brain barrier permeability

Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity

Development of versatile and potent monoquaternary reactivators of acetylcholinesterase

Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile

Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer’s Disease

Plant functional groups and phylogenetic regularity control plant community bioelement composition through calcium and magnesium

2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer’s disease

Exploring Structure-Activity Relationship in Tacrine-Squaramide Derivatives as Potent Cholinesterase Inhibitors

Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods

Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication

Stoichiometry versus ecology: the relationships between genome size and guanine-cytosine content, and tissue nitrogen and phosphorus in grassland herbs

New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H3 Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties

Disentangling the taxonomic structure of the Allium paniculatum species complex in central and eastern Europe using molecular, cytogenetic and morphological tools

First insight into the genomes of the Pulmonaria officinalis group (Boraginaceae) provided by repeatome analysis and comparative karyotyping

Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects

First insights into the evolution of genome size in the borage family: a complete data set for Boraginaceae from the Czech Republic

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