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Host gene expression classifiers diagnose acute respiratory illness etiology

Science translational medicine, 2016-01, Vol.8 (322), p.322ra11

2016

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An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

Genome medicine, 2021-05, Vol.13 (1), p.83-83, Article 83

2021

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A comparison of host response strategies to distinguish bacterial and viral infection

PloS one, 2021-12, Vol.16 (12), p.e0261385-e0261385

2021

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Systematic comparison of published host gene expression signatures for bacterial/viral discrimination

Genome medicine, 2022-02, Vol.14 (1), p.18-18, Article 18

2022

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A host gene expression approach for identifying triggers of asthma exacerbations

PloS one, 2019-04, Vol.14 (4), p.e0214871-e0214871

2019

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Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion

Scientific reports, 2022-07, Vol.12 (1), p.11714-13, Article 11714

2022

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The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood

Frontiers in immunology, 2021-10, Vol.12, p.741837-741837

2021

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Author Correction: Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion

Scientific reports, 2023-04, Vol.13 (1), p.6462-6462, Article 6462

2023

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Validation of a host response test to distinguish bacterial and viral respiratory infection

EBioMedicine, 2019-10, Vol.48, p.453-461

2019

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Direct-from-blood RNA sequencing identifies the cause of post-bronchoscopy fever

BMC infectious diseases, 2019-10, Vol.19 (1), p.905-905, Article 905

2019

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A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies

Frontiers in microbiology, 2018-12, Vol.9, p.2957-2957

2018

Volltextzugriff (PDF)

Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test

Critical care medicine, 2021-10, Vol.49 (10), p.1651

2021

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The host response as a tool for infectious disease diagnosis and management

Expert review of molecular diagnostics, 2018-08, Vol.18 (8), p.723-738

2018

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Average Weighted Accuracy: Pragmatic Analysis for a Rapid Diagnostics in Categorizing Acute Lung Infections (RADICAL) Study

Clinical infectious diseases, 2020-06, Vol.70 (12), p.2736-2742

2020

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Host Gene Expression to Predict Sepsis Progression

Critical care medicine, 2022-12, Vol.50 (12), p.1748

2022

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A New Era in Host Response Biomarkers to Guide Precision Medicine for Infectious Diseases

Journal of the Pediatric Infectious Diseases Society, 2022-12, Vol.11 (11), p.477-479

2022

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Insight into septic subpopulations from proteomic trajectory clusters

Journal of critical care, 2023-04, Vol.74, p.154206, Article 154206

2023

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Multi-layer gene bundling: A new approach to gene clustering

Journal of critical care, 2023-04, Vol.74, p.154201, Article 154201

2023

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Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The “PRONE” Study

Contemporary clinical trials, 2021-10, Vol.109, p.106541-106541, Article 106541

2021

Volltextzugriff (PDF)

Mucosal-associated invariant T cell responses differ by sex in COVID-19

Med (New York, N.Y. : Online), 2021-06, Vol.2 (6), p.755-772.e5

2021

Volltextzugriff (PDF)

What was old is new again: using the host response to diagnose infectious disease

Expert review of molecular diagnostics, 2015-09, Vol.15 (9), p.1143-1158

2015

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Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis

Science advances, 2017-03, Vol.3 (3), p.e1602096-e1602096

2017

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Single-cell genome-wide association reveals that a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus

Cell genomics, 2022-11, Vol.2 (11), p.100207, Article 100207

2022

Volltextzugriff (PDF)

Comparing the Diagnostic Accuracy of Clinician Judgment to a Novel Host Response Diagnostic for Acute Respiratory Illness

Open forum infectious diseases, 2021-12, Vol.8 (12), p.ofab564-ofab564

2021

Volltextzugriff (PDF)

Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population

Open forum infectious diseases, 2020-06, Vol.7 (6), p.ofaa194-ofaa194

2020

Volltextzugriff (PDF)

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Host gene expression classifiers diagnose acute respiratory illness etiology

An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

A comparison of host response strategies to distinguish bacterial and viral infection

Systematic comparison of published host gene expression signatures for bacterial/viral discrimination

A host gene expression approach for identifying triggers of asthma exacerbations

Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion

The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood

Author Correction: Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion

Validation of a host response test to distinguish bacterial and viral respiratory infection

Direct-from-blood RNA sequencing identifies the cause of post-bronchoscopy fever

A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies

Discriminating Bacterial and Viral Infection Using a Rapid Host Gene Expression Test

The host response as a tool for infectious disease diagnosis and management

Average Weighted Accuracy: Pragmatic Analysis for a Rapid Diagnostics in Categorizing Acute Lung Infections (RADICAL) Study

Host Gene Expression to Predict Sepsis Progression

A New Era in Host Response Biomarkers to Guide Precision Medicine for Infectious Diseases

Insight into septic subpopulations from proteomic trajectory clusters

Multi-layer gene bundling: A new approach to gene clustering

Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The “PRONE” Study

Mucosal-associated invariant T cell responses differ by sex in COVID-19

What was old is new again: using the host response to diagnose infectious disease

Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis

Single-cell genome-wide association reveals that a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus

Comparing the Diagnostic Accuracy of Clinician Judgment to a Novel Host Response Diagnostic for Acute Respiratory Illness

Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population

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