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Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

Cell, 2012-02, Vol.148 (3), p.434-446

2012

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Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor

PLoS neglected tropical diseases, 2021-10, Vol.15 (10), p.e0009224-e0009224

2021

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Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk

Cell, 2017-03, Vol.169 (1), p.72-84.e13

2017

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An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

Genome medicine, 2021-05, Vol.13 (1), p.83-83, Article 83

2021

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Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host–pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides

Molecular microbiology, 2015-09, Vol.97 (5), p.844-865

2015

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ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice

PLoS pathogens, 2021-07, Vol.17 (7), p.e1009713-e1009713

2021

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Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10

Cell reports (Cambridge), 2018-06, Vol.23 (12), p.3525-3536

2018

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The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

PLoS pathogens, 2016-07, Vol.12 (7), p.e1005680-e1005680

2016

Volltextzugriff (PDF)

Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions

mBio, 2022-06, Vol.13 (3), p.e0346421-e0346421

2022

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Multiple Surface Regions on the Niemann-Pick C2 Protein Facilitate Intracellular Cholesterol Transport

The Journal of biological chemistry, 2015-11, Vol.290 (45), p.27321-27331

2015

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Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages

mBio, 2024-04, Vol.15 (4), p.e0045424

2024

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The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

eLife, 2023-06, Vol.12

2023

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Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS

PLoS pathogens, 2013-08, Vol.9 (8), p.e1003424-e1003424

2013

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An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection

PloS one, 2013-07, Vol.8 (7), p.e67828-e67828

2013

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A real-time PCR assay for quantification of parasite burden in murine models of leishmaniasis

PeerJ (San Francisco, CA), 2018-11, Vol.6, p.e5905-e5905, Article e5905

2018

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Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease

PLoS genetics, 2005-07, Vol.1 (1), p.81-95

2005

Volltextzugriff (PDF)

Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (35), p.13900-13901

2012

Volltextzugriff (PDF)

CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation

Genome Biology, 2015-09, Vol.16 (1), p.190-190, Article 190

2015

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Th17 Immunity in the Colon Is Controlled by Two Novel Subsets of Colon-Specific Mononuclear Phagocytes

Frontiers in immunology, 2021-04, Vol.12, p.661290

2021

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Binding between the Niemann-Pick C1 Protein and a Photoactivatable Cholesterol Analog Requires a Functional Sterol-Sensing Domain

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (34), p.12473-12478

2004

Volltextzugriff (PDF)

The Awesome Power of Human Genetics of Infectious Disease

Annual review of genetics, 2022-11, Vol.56, p.41

2022

Volltextzugriff (PDF)

The Integrity of a Cholesterol-Binding Pocket in Niemann-Pick C2 Protein Is Necessary to Control Lysosome Cholesterol Levels

Proceedings of the National Academy of Sciences - PNAS, 2003-03, Vol.100 (5), p.2518-2525

2003

Volltextzugriff (PDF)

Human genetic diversity regulating the TLR10/TLR1/TLR6 locus confers increased cytokines in response to Chlamydia trachomatis

HGG advances, 2022-01, Vol.3 (1), p.100071-100071, Article 100071

2022

Volltextzugriff (PDF)

The phorbol 12-myristate-13-acetate differentiation protocol is critical to the interaction of THP-1 macrophages with Salmonella Typhimurium

PloS one, 2018-03, Vol.13 (3), p.e0193601-e0193601

2018

Volltextzugriff (PDF)

These Are the Genes You’re Looking For: Finding Host Resistance Genes

Trends in microbiology (Regular ed.), 2021-04, Vol.29 (4), p.346-362

2021

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Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections

Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor

Human Epistatic Interaction Controls IL7R Splicing and Increases Multiple Sclerosis Risk

An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility

Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host–pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides

ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice

Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10

The Legacy of Past Pandemics: Common Human Mutations That Protect against Infectious Disease

Integration of the Salmonella Typhimurium Methylome and Transcriptome Reveals That DNA Methylation and Transcriptional Regulation Are Largely Decoupled under Virulence-Related Conditions

Multiple Surface Regions on the Niemann-Pick C2 Protein Facilitate Intracellular Cholesterol Transport

Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages

The RNA helicase DDX39B activates FOXP3 RNA splicing to control T regulatory cell fate

Understanding human variation in infectious disease susceptibility through clinical and cellular GWAS

An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection

A real-time PCR assay for quantification of parasite burden in murine models of leishmaniasis

Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease

Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death

CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation

Th17 Immunity in the Colon Is Controlled by Two Novel Subsets of Colon-Specific Mononuclear Phagocytes

Binding between the Niemann-Pick C1 Protein and a Photoactivatable Cholesterol Analog Requires a Functional Sterol-Sensing Domain

The Awesome Power of Human Genetics of Infectious Disease

The Integrity of a Cholesterol-Binding Pocket in Niemann-Pick C2 Protein Is Necessary to Control Lysosome Cholesterol Levels

Human genetic diversity regulating the TLR10/TLR1/TLR6 locus confers increased cytokines in response to Chlamydia trachomatis

The phorbol 12-myristate-13-acetate differentiation protocol is critical to the interaction of THP-1 macrophages with Salmonella Typhimurium

These Are the Genes You’re Looking For: Finding Host Resistance Genes

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