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Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism

The Journal of biological chemistry, 2019-11, Vol.294 (47), p.17799-17817

2019

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Metabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritis

Scientific reports, 2021-07, Vol.11 (1), p.15131-15131, Article 15131

2021

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CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention

Matrix biology, 2016-12, Vol.56, p.74-94

2016

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Simvastatin promotes restoration of chondrocyte morphology and phenotype

Archives of biochemistry and biophysics, 2019-04, Vol.665, p.1-11

2019

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Hyaluronan synthase 2 (HAS2) overexpression diminishes the procatabolic activity of chondrocytes by a mechanism independent of extracellular hyaluronan

The Journal of biological chemistry, 2019-09, Vol.294 (37), p.13562-13579

2019

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Suppression of murine osteoarthritis by 4‐methylumbelliferone

Journal of orthopaedic research, 2020-05, Vol.38 (5), p.1122-1131

2020

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4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition

The Journal of biological chemistry, 2016-06, Vol.291 (23), p.12087-12104

2016

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Extracellular Processing of the Cartilage Proteoglycan Aggregate and Its Effect on CD44-mediated Internalization of Hyaluronan

The Journal of biological chemistry, 2015-04, Vol.290 (15), p.9555-9570

2015

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CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex

Immunity (Cambridge, Mass.), 2006-10, Vol.25 (4), p.595-606

2006

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CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2

Matrix biology, 2015-10, Vol.48, p.42-54

2015

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Inhibition of CD44 intracellular domain production suppresses bovine articular chondrocyte de-differentiation induced by excessive mechanical stress loading

Scientific reports, 2019-10, Vol.9 (1), p.14901-10, Article 14901

2019

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Acylation of CD44 and Its Association with Lipid Rafts Are Required for Receptor and Hyaluronan Endocytosis

The Journal of biological chemistry, 2006-11, Vol.281 (45), p.34601-34609

2006

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Therapeutic potential of hyaluronan oligosaccharides for bone metastasis of breast cancer

Journal of orthopaedic research, 2012-04, Vol.30 (4), p.662-672

2012

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CD44 and Hyaluronan Promote the Bone Morphogenetic Protein 7 Signaling Response in Murine Chondrocytes

Arthritis & rheumatology (Hoboken, N.J.), 2014-06, Vol.66 (6), p.1547-1558

2014

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Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides

Arthritis & rheumatology (Hoboken, N.J.), 2012-01, Vol.64 (1), p.187-197

2012

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Matrix Metalloproteinase-12 Is Required for Granuloma Progression

Frontiers in immunology, 2020-09, Vol.11, p.553949

2020

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Chondroprotective Effect of Kartogenin on CD44-Mediated Functions in Articular Cartilage and Chondrocytes

Cartilage, 2014-07, Vol.5 (3), p.172-180

2014

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Hyaluronan Oligosaccharides Inhibit Tumorigenicity of Osteosarcoma Cell Lines MG-63 and LM-8 in Vitro and in Vivo via Perturbation of Hyaluronan-Rich Pericellular Matrix of the Cells

The American journal of pathology, 2007-07, Vol.171 (1), p.274-286

2007

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Chondrogenic capacity and alterations in hyaluronan synthesis of cultured human osteoarthritic chondrocytes

Biochemical and biophysical research communications, 2013-06, Vol.435 (4), p.733-739

2013

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Internalization of Aggrecan G1 Domain Neoepitope ITEGE in Chondrocytes Requires CD44

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.36216-36224

2010

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Hyaluronan regulates synapse formation and function in developing neural networks

Scientific reports, 2020-10, Vol.10 (1), p.16459, Article 16459

2020

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The pericellular hyaluronan of articular chondrocytes

Matrix biology, 2019-05, Vol.78-79, p.32-46

2019

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A Requirement for the CD44 Cytoplasmic Domain for Hyaluronan Binding, Pericellular Matrix Assembly, and Receptor-mediated Endocytosis in COS-7 Cells

The Journal of biological chemistry, 2002-03, Vol.277 (12), p.10531-10538

2002

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CD44 Modulates Smad1 Activation in the BMP-7 Signaling Pathway

The Journal of cell biology, 2004-09, Vol.166 (7), p.1081-1091

2004

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Iduronic Acid-Containing Glycosaminoglycans on Target Cells Are Required for Efficient Respiratory Syncytial Virus Infection

Virology (New York, N.Y.), 2000-06, Vol.271 (2), p.264-275

2000

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Chondroprotective effects of 4-methylumbelliferone and hyaluronan synthase-2 overexpression involve changes in chondrocyte energy metabolism

Metabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritis

CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention

Simvastatin promotes restoration of chondrocyte morphology and phenotype

Hyaluronan synthase 2 (HAS2) overexpression diminishes the procatabolic activity of chondrocytes by a mechanism independent of extracellular hyaluronan

Suppression of murine osteoarthritis by 4‐methylumbelliferone

4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition

Extracellular Processing of the Cartilage Proteoglycan Aggregate and Its Effect on CD44-mediated Internalization of Hyaluronan

CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex

CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2

Inhibition of CD44 intracellular domain production suppresses bovine articular chondrocyte de-differentiation induced by excessive mechanical stress loading

Acylation of CD44 and Its Association with Lipid Rafts Are Required for Receptor and Hyaluronan Endocytosis

Therapeutic potential of hyaluronan oligosaccharides for bone metastasis of breast cancer

CD44 and Hyaluronan Promote the Bone Morphogenetic Protein 7 Signaling Response in Murine Chondrocytes

Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides

Matrix Metalloproteinase-12 Is Required for Granuloma Progression

Chondroprotective Effect of Kartogenin on CD44-Mediated Functions in Articular Cartilage and Chondrocytes

Hyaluronan Oligosaccharides Inhibit Tumorigenicity of Osteosarcoma Cell Lines MG-63 and LM-8 in Vitro and in Vivo via Perturbation of Hyaluronan-Rich Pericellular Matrix of the Cells

Chondrogenic capacity and alterations in hyaluronan synthesis of cultured human osteoarthritic chondrocytes

Internalization of Aggrecan G1 Domain Neoepitope ITEGE in Chondrocytes Requires CD44

Hyaluronan regulates synapse formation and function in developing neural networks

The pericellular hyaluronan of articular chondrocytes

A Requirement for the CD44 Cytoplasmic Domain for Hyaluronan Binding, Pericellular Matrix Assembly, and Receptor-mediated Endocytosis in COS-7 Cells

CD44 Modulates Smad1 Activation in the BMP-7 Signaling Pathway

Iduronic Acid-Containing Glycosaminoglycans on Target Cells Are Required for Efficient Respiratory Syncytial Virus Infection

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