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Roche and Obesity

Nature (London), 2000-04, Vol.404 (6778), p.678-679

Knowles, Jonathan K.C

2000

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The three-dimensional crystal structure of the catalytic core of cellobiohydrolase I from Trichoderma reesei

Science (American Association for the Advancement of Science), 1994-07, Vol.265 (5171), p.524-528

1994

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Efficient secretion of two fungal cellobiohydrolases by Saccharomyces cerevisiae

Gene, 1988, Vol.63 (1), p.103-112

1988

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Domain function in Trichoderma reesei cellobiohydrolases

Journal of biotechnology, 1992-01, Vol.24 (2), p.169-176

1992

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Enzyme production by recombinant Trichoderma reesei strains

Journal of biotechnology, 1991, Vol.17 (1), p.35-49

1991

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Random mutagenesis used to probe the structure and function of Bacillus stearothermophilus alpha-amylase

Protein engineering, 1990-01, Vol.3 (3), p.181-191

1990

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Abstract 4580: Personalized treatment selection for therapy-resistant AML by integrating ex-vivo drug sensitivity and resistance testing (DSRT) as well as serial genomic, transcriptomic and phosphoproteomic profiling

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.4580-4580

2012

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Efficient secretion of murine Fab fragments by Escherichia coli is determined by the first constant domain of the heavy chain

Gene, 1993-06, Vol.128 (2), p.203-209

1993

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Site-directed mutagenesis of the putative catalytic residues of Trichoderma reesci cellobiohydrolase I and endoglucanase I

FEBS letters, 1990-11, Vol.275 (1), p.135-138

1990

Volltextzugriff (PDF)

Investigation of the function of mutated cellulose-binding domains of Trichoderma reesei cellobiohydrolase I

Proteins, structure, function, and bioinformatics, 1992-12, Vol.14 (4), p.475-482

1992

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Efficient production of antibody fragments by the filamentous fungus Trichoderma reesei

Bio/technology (New York, N.Y. 1983), 1993-05, Vol.11 (5), p.591-595

1993

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Using human genetics and genomics to discover better therapies

Pharmacological research, 1995, Vol.31, p.21-21

Knowles, Jonathan K.C.

1995

Volltextzugriff (PDF)

Diagnostics and the Future of Medicine

Clinical chemistry and laboratory medicine, 2000-09, Vol.38 (9), p.804-804

Knowles, J K

2000

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An active single-chain antibody containing a cellulase linker domain is secreted by Escherichia coli

Protein engineering, 1991-10, Vol.4 (7), p.837-841

1991

Volltextzugriff (PDF)

Structural homology among the peroxidase enzyme family revealed by hydrophobic cluster analysis

Proteins, structure, function, and bioinformatics, 1990, Vol.8 (3), p.251-257

1990

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A lignin peroxidase-encoding cDNA from the white-rot fungus Phlebia radiata: characterization and expression in Trichoderma reesei

Gene, 1989-12, Vol.85 (2), p.343-351

1989

Volltextzugriff (PDF)

A Ca(2+)-independent protein kinase C from fission yeast

The Journal of biological chemistry, 1993-04, Vol.268 (10), p.7401-7406

1993

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Expression of two Trichoderma reesei endoglucanases in the yeast Saccharomyces cerevisiae

Yeast (Chichester, England), 1987-09, Vol.3 (3), p.175-185

1987

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Characterization of a birch (Betula pendula Roth.) embryogenic gene, BP8

Plant molecular biology, 1993-10, Vol.23 (2), p.423-428

1993

Volltextzugriff (PDF)

Molecular modelling study of antigen binding to oxazolone-specific antibodies: the Ox1 idiotypic IgG and its mature variant with increased affinity to 2-phenyloxazolone

Protein engineering, 1990-04, Vol.3 (5), p.403-409

1990

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Efficient secretion of Bacillus amyloliquefaciens α-amylase cells by its own signal peptide from Saccharomyces cerevisiae host

Gene, 1987, Vol.59 (2), p.161-170

1987

Volltextzugriff (PDF)

Modelling of the lignin peroxidase LIII of Phlebia radiata: use of a sequence template generated from a 3-D structure

Protein engineering, 1993-02, Vol.6 (2), p.177-182

1993

Volltextzugriff (PDF)

Efficient secretion of Bacillus amyloliquefaciens α-amylase cells by its own signal peptide from Saccharomyces cerevisiae host cells

Gene, 1988-04, Vol.64 (2), p.327-327

1988

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Molecular cloning of cellulolytic enzyme genes from Cellulomonas flavigena in E. coli

Journal of biotechnology, 1988, Vol.8 (3), p.249-255

1988

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Cloning of Aspergillus niger genes in yeast. Expression of the gene coding Aspergillus beta-glucosidase

Molecular & general genetics, 1984-01, Vol.194 (3), p.494-499

1984

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Roche and Obesity

The three-dimensional crystal structure of the catalytic core of cellobiohydrolase I from Trichoderma reesei

Efficient secretion of two fungal cellobiohydrolases by Saccharomyces cerevisiae

Domain function in Trichoderma reesei cellobiohydrolases

Enzyme production by recombinant Trichoderma reesei strains

Random mutagenesis used to probe the structure and function of Bacillus stearothermophilus alpha-amylase

Abstract 4580: Personalized treatment selection for therapy-resistant AML by integrating ex-vivo drug sensitivity and resistance testing (DSRT) as well as serial genomic, transcriptomic and phosphoproteomic profiling

Efficient secretion of murine Fab fragments by Escherichia coli is determined by the first constant domain of the heavy chain

Site-directed mutagenesis of the putative catalytic residues of Trichoderma reesci cellobiohydrolase I and endoglucanase I

Investigation of the function of mutated cellulose-binding domains of Trichoderma reesei cellobiohydrolase I

Efficient production of antibody fragments by the filamentous fungus Trichoderma reesei

Using human genetics and genomics to discover better therapies

Diagnostics and the Future of Medicine

An active single-chain antibody containing a cellulase linker domain is secreted by Escherichia coli

Structural homology among the peroxidase enzyme family revealed by hydrophobic cluster analysis

A lignin peroxidase-encoding cDNA from the white-rot fungus Phlebia radiata: characterization and expression in Trichoderma reesei

A Ca(2+)-independent protein kinase C from fission yeast

Expression of two Trichoderma reesei endoglucanases in the yeast Saccharomyces cerevisiae

Characterization of a birch (Betula pendula Roth.) embryogenic gene, BP8

Molecular modelling study of antigen binding to oxazolone-specific antibodies: the Ox1 idiotypic IgG and its mature variant with increased affinity to 2-phenyloxazolone

Efficient secretion of Bacillus amyloliquefaciens α-amylase cells by its own signal peptide from Saccharomyces cerevisiae host

Modelling of the lignin peroxidase LIII of Phlebia radiata: use of a sequence template generated from a 3-D structure

Efficient secretion of Bacillus amyloliquefaciens α-amylase cells by its own signal peptide from Saccharomyces cerevisiae host cells

Molecular cloning of cellulolytic enzyme genes from Cellulomonas flavigena in E. coli

Cloning of Aspergillus niger genes in yeast. Expression of the gene coding Aspergillus beta-glucosidase

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