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Epigenetic mechanisms of tumorigenicity manifesting in stem cells

Oncogene, 2015-04, Vol.34 (18), p.2288-2296

2015

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N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

Genes & development, 2002-10, Vol.16 (20), p.2699-2712

2002

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The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1

Molecular and Cellular Biology, 1995-10, Vol.15 (10), p.5811-5819

1995

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Pbx Marks Genes for Activation by MyoD Indicating a Role for a Homeodomain Protein in Establishing Myogenic Potential

Molecular cell, 2004-05, Vol.14 (4), p.465-477

2004

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A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1

Nucleic acids research, 1999-09, Vol.27 (18), p.3752-3767

1999

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Sin Meets NuRD and Other Tails of Repression

Cell, 1999-11, Vol.99 (5), p.447-450

1999

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Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes

Molecular and Cellular Biology, 1995-07, Vol.15 (7), p.3786-3795

1995

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Pbx1-Hox Heterodimers Bind DNA on Inseparable Half-Sites That Permit Intrinsic DNA Binding Specificity of the Hox Partner at Nucleotides 3' to a TAAT Motif

Nucleic acids research, 1996-06, Vol.24 (12), p.2288-2294

1996

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The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I hox proteins : evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements

Oncogene, 1997-05, Vol.14 (21), p.2521-2531

1997

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Meis1a Suppresses Differentiation by G-CSF and Promotes Proliferation by SCF: Potential Mechanisms of Cooperativity with Hoxa9 in Myeloid Leukemia

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (23), p.13120-13125

2001

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Meis1 and pKnox1 Bind DNA Cooperatively with Pbx1 Utilizing an Interaction Surface Disrupted in Oncoprotein E2a-Pbx1

Proceedings of the National Academy of Sciences - PNAS, 1997-12, Vol.94 (26), p.14553-14558

1997

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Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors

Cold Spring Harbor Symposia on Quantitative Biology, 2005, Vol.70, p.299-307

2005

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HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation

Oncogene, 2001-09, Vol.20 (39), p.5440-5448

2001

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The Smad transcriptional corepressor TGIF recruits mSin3

Cell growth & differentiation, 2001-09, Vol.12 (9), p.457-463

2001

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Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Development (Cambridge), 2005-03, Vol.132 (6), p.1363-1374

2005

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Neural Precursor Cycling at Sonic Speed: N-Myc Pedals, GSK-3 Brakes

Cell cycle (Georgetown, Tex.), 2006-01, Vol.5 (1), p.47-52

2006

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Urokinase plasminogen activator activity is increased in the myocardium during coronary artery occlusion

Journal of molecular and cellular cardiology, 1995-06, Vol.27 (6), p.1317-1324

1995

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HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations

Nature structural & molecular biology, 2004-08, Vol.11 (8), p.738-746

2004

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Direct interaction of two homeoproteins, Homothorax and Extradenticle, is essential for EXD nuclear localization and function

Mechanisms of development, 2000-03, Vol.91 (1), p.279-291

2000

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The Pbx family of proteins is strongly upregulated by a post-transcriptional mechanism during retinoic acid-induced differentiation of P19 embryonal carcinoma cells

Mechanisms of development, 1997-04, Vol.63 (1), p.5-14

1997

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Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif

Nucleic acids research, 1996-06, Vol.24 (12), p.2288

1996

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Gene Expression in a Swine Model of Right Ventricular Hypertrophy: Intercellular Adhesion Molecule, Vascular Endothelial Growth Factor and Plasminogen Activators are Upregulated during Pressure Overload

Journal of molecular and cellular cardiology, 1995-07, Vol.27 (7), p.1427-1441

1995

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Potential antidepressant overtreatment associated with office use of brief depression symptom measures

Journal of the American Board of Family Medicine, 2014-09, Vol.27 (5), p.611-620

2014

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N-myc coordinates retinal growth with eye size during mouse development

Genes & development, 2008-01, Vol.22 (2), p.179-193

2008

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Recent surface displacements in the Upper Rhine Graben — Preliminary results from geodetic networks

Tectonophysics, 2013-08, Vol.602, p.300-315

2013

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Epigenetic mechanisms of tumorigenicity manifesting in stem cells

N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation

The pentapeptide motif of Hox proteins is required for cooperative DNA binding with Pbx1, physically contacts Pbx1, and enhances DNA binding by Pbx1

Pbx Marks Genes for Activation by MyoD Indicating a Role for a Homeodomain Protein in Establishing Myogenic Potential

A conserved motif N-terminal to the DNA-binding domains of myogenic bHLH transcription factors mediates cooperative DNA binding with pbx-Meis1/Prep1

Sin Meets NuRD and Other Tails of Repression

Both Pbx1 and E2A-Pbx1 bind the DNA motif ATCAATCAA cooperatively with the products of multiple murine Hox genes, some of which are themselves oncogenes

Pbx1-Hox Heterodimers Bind DNA on Inseparable Half-Sites That Permit Intrinsic DNA Binding Specificity of the Hox Partner at Nucleotides 3' to a TAAT Motif

The highest affinity DNA element bound by Pbx complexes in t(1;19) leukemic cells fails to mediate cooperative DNA-binding or cooperative transactivation by E2a-Pbx1 and class I hox proteins : evidence for selective targetting of E2a-Pbx1 to a subset of Pbx-recognition elements

Meis1a Suppresses Differentiation by G-CSF and Promotes Proliferation by SCF: Potential Mechanisms of Cooperativity with Hoxa9 in Myeloid Leukemia

Meis1 and pKnox1 Bind DNA Cooperatively with Pbx1 Utilizing an Interaction Surface Disrupted in Oncoprotein E2a-Pbx1

Genomic binding and transcriptional regulation by the Drosophila Myc and Mnt transcription factors

HoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation

The Smad transcriptional corepressor TGIF recruits mSin3

Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation

Neural Precursor Cycling at Sonic Speed: N-Myc Pedals, GSK-3 Brakes

Urokinase plasminogen activator activity is increased in the myocardium during coronary artery occlusion

HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations

Direct interaction of two homeoproteins, Homothorax and Extradenticle, is essential for EXD nuclear localization and function

The Pbx family of proteins is strongly upregulated by a post-transcriptional mechanism during retinoic acid-induced differentiation of P19 embryonal carcinoma cells

Pbx-1 Hox heterodimers bind DNA on inseparable half-sites that permit intrinsic DNA binding specificity of the Hox partner at nucleotides 3' to a TAAT motif

Gene Expression in a Swine Model of Right Ventricular Hypertrophy: Intercellular Adhesion Molecule, Vascular Endothelial Growth Factor and Plasminogen Activators are Upregulated during Pressure Overload

Potential antidepressant overtreatment associated with office use of brief depression symptom measures

N-myc coordinates retinal growth with eye size during mouse development

Recent surface displacements in the Upper Rhine Graben — Preliminary results from geodetic networks

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