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Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy

Bioorganic & medicinal chemistry letters, 2018-08, Vol.28 (15), p.2655-2659

2018

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Targeted covalent drugs of the kinase family

Current opinion in chemical biology, 2010-08, Vol.14 (4), p.475-480

2010

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Acylating drugs: redesigning natural covalent inhibitors

Current opinion in chemical biology, 2010-06, Vol.14 (3), p.421-427

2010

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Addressing hERG activity while maintaining favorable potency, selectivity and pharmacokinetic properties of PPARδ modulators

Bioorganic & medicinal chemistry letters, 2020-02, Vol.30 (4), p.126928, Article 126928

2020

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Novel highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulators with pharmacokinetic properties suitable for once-daily oral dosing

Bioorganic & medicinal chemistry letters, 2017-12, Vol.27 (23), p.5230-5234

2017

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Highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulator demonstrates improved safety profile compared to GW501516

Bioorganic & medicinal chemistry letters, 2018-02, Vol.28 (3), p.533-536

2018

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Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD)

ACS medicinal chemistry letters, 2018-09, Vol.9 (9), p.935-940

2018

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Correction to “Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD)”

ACS medicinal chemistry letters, 2019-06, Vol.10 (6), p.1013-1013

2019

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A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase

Bioorganic & medicinal chemistry letters, 2001-02, Vol.11 (4), p.541-544

2001

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Antifungal activity of a Candida albicans GGTase I inhibitor-Alanine conjugate. inhibition of Rho1p prenylation in C. albicans

Bioorganic & medicinal chemistry letters, 2003-06, Vol.13 (11), p.1935-1937

2003

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Potent prostacyclin analogs based on the bicyclo[4.2.0]octane ring system

Journal of organic chemistry, 1987-06, Vol.52 (13), p.2860-2868

1987

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Synthesis and antihypertensive activity of 4'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-ones

Journal of medicinal chemistry, 1983-05, Vol.26 (5), p.657-661

1983

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Phosphonate reagents for the synthesis of enol ethers and one-carbon homologation to aldehydes

Journal of organic chemistry, 1979-12, Vol.44 (26), p.4847-4852

1979

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Synthesis of 1,7-dioxaspiro[5.5]undecanes

Heterocycles, 1986-06, Vol.24 (6), p.1699-1740

KLUGE, A. F

1986

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Synthesis of (20R,25R)-cholest-5-ene-3.beta.,26-diol and the occurrence of base-catalyzed 1,5-hydride shift in a steroidal 1,5-ketol

Journal of organic chemistry, 1985-06, Vol.50 (13), p.2359-2365

1985

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Application of bakers' yeast-mediated reductions of bicyclo[4.2.0]oct-2-en-7-ones to the enantioselective synthesis of prostacyclin analogs

Journal of organic chemistry, 1988-10, Vol.53 (21), p.4962-4968

1988

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Synthesis, antiinflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and related compounds

Journal of medicinal chemistry, 1985-08, Vol.28 (8), p.1037-1049

1985

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Prostaglandins. X. Synthesis of prostaglandin models and prostaglandins by conjugage addition of a functionalized organocopper reagent

Journal of the American Chemical Society, 1972-11, Vol.94 (22), p.7827-7832

1972

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Synthesis and structure-activity relationships of a series of novel thiazoles as inhibitors of aminoacyl-tRNA synthetases

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (3), p.375-380

1999

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Synthesis and antihypertensive activity of a series of spiro[1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizine-2,5'-oxazolidin-2'-one]s

Journal of medicinal chemistry, 1983-10, Vol.26 (10), p.1426-1433

1983

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Molecular spectra and conformations of conjugated dienones

Journal of organic chemistry, 1971-07, Vol.36 (14), p.1977-1988

1971

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Synthetic studies in the ajmaline series

Journal of organic chemistry, 1982-03, Vol.47 (6), p.919-928

1982

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The enantiospecific Nicholas reaction

Tetrahedron letters, 1994-11, Vol.35 (47), p.8755-8758

1994

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Novel highly selective inhibitors of ubiquitin specific protease 30 (USP30) accelerate mitophagy

Targeted covalent drugs of the kinase family

Acylating drugs: redesigning natural covalent inhibitors

Addressing hERG activity while maintaining favorable potency, selectivity and pharmacokinetic properties of PPARδ modulators

Novel highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulators with pharmacokinetic properties suitable for once-daily oral dosing

Highly selective peroxisome proliferator-activated receptor δ (PPARδ) modulator demonstrates improved safety profile compared to GW501516

Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD)

Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

Correction to “Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD)”

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours

A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase

Antifungal activity of a Candida albicans GGTase I inhibitor-Alanine conjugate. inhibition of Rho1p prenylation in C. albicans

Potent prostacyclin analogs based on the bicyclo[4.2.0]octane ring system

Synthesis and antihypertensive activity of 4'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-ones

Phosphonate reagents for the synthesis of enol ethers and one-carbon homologation to aldehydes

Synthesis of 1,7-dioxaspiro[5.5]undecanes

Synthesis of (20R,25R)-cholest-5-ene-3.beta.,26-diol and the occurrence of base-catalyzed 1,5-hydride shift in a steroidal 1,5-ketol

Application of bakers' yeast-mediated reductions of bicyclo[4.2.0]oct-2-en-7-ones to the enantioselective synthesis of prostacyclin analogs

Synthesis, antiinflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids and related compounds

Prostaglandins. X. Synthesis of prostaglandin models and prostaglandins by conjugage addition of a functionalized organocopper reagent

Synthesis and structure-activity relationships of a series of novel thiazoles as inhibitors of aminoacyl-tRNA synthetases

Synthesis and antihypertensive activity of a series of spiro[1,3,4,6,7,11b-hexahydro-2H-benzo[a]quinolizine-2,5'-oxazolidin-2'-one]s

Molecular spectra and conformations of conjugated dienones

Synthetic studies in the ajmaline series

The enantiospecific Nicholas reaction

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