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Progesterone Inhibition of Wnt/β-Catenin Signaling in Normal Endometrium and Endometrial Cancer

Clinical cancer research, 2009-09, Vol.15 (18), p.5784-5793

2009

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Tissue-selectivity: the mechanism of action of tibolone

Maturitas, 2004-08, Vol.48, p.30-40

Kloosterboer, Helenius J.

2004

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Estetrol prevents and suppresses mammary tumors induced by DMBA in a rat model

Hormone molecular biology and clinical investigation, 2012-04, Vol.9 (1), p.95-103

2012

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Metabolism of the synthetic progestogen norethynodrel by human ketosteroid reductases of the aldo–keto reductase superfamily

The Journal of steroid biochemistry and molecular biology, 2012-04, Vol.129 (3-5), p.139-144

2012

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Human Cytosolic Hydroxysteroid Dehydrogenases of the Aldo-ketoreductase Superfamily Catalyze Reduction of Conjugated Steroids: IMPLICATIONS FOR PHASE I AND PHASE II STEROID HORMONE METABOLISM

The Journal of biological chemistry, 2009-04, Vol.284 (15), p.10013-10022

2009

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Antioxidant effect of the active metabolites of tibolone

Gynecological endocrinology, 2015-01, Vol.31 (1), p.31-35

2015

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Progestins induce catalase activities in breast cancer cells through PRB isoform: Correlation with cell growth inhibition

The Journal of steroid biochemistry and molecular biology, 2009-07, Vol.115 (3), p.153-160

2009

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Receptor profiling and endocrine interactions of tibolone

Steroids, 2003, Vol.68 (1), p.21-30

2003

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Hormonal regulation of apoptosis in breast cells and tissues

Steroids, 2000-10, Vol.65 (10), p.593-598

2000

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In vitro studies of tibolone in breast cells

Fertility and sterility, 2002-08, Vol.78 (2), p.351-359

2002

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Effect of tibolone and raloxifene on the tail temperature of oestrogen-deficient rats

European journal of pharmacology, 2001-05, Vol.419 (1), p.47-54

2001

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Effects of tibolone on nuclear receptors in human endometrial cells

American journal of obstetrics and gynecology, 2006-07, Vol.195 (1), p.97-102

2006

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Tibolone: a compound with tissue specific inhibitory effects on sulfatase

Molecular and cellular endocrinology, 2001-10, Vol.183 (1), p.55-62

2001

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Metabolism of estradiol, ethynylestradiol, and moxestrol in rat uterus, vagina, and aorta: influence of sex steroid treatment

Drug metabolism and disposition, 2001-01, Vol.29 (1), p.76

2001

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Hormone replacement therapy dependent changes in breast cancer-related gene expression in breast tissue of healthy postmenopausal women

Molecular oncology, 2011-12, Vol.5 (6), p.504-516

2011

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Effects of Tibolone Metabolites on Human Endometrial Cell Lines in Co-culture

Reproductive sciences (Thousand Oaks, Calif.), 2008-01, Vol.15 (1), p.75-82

2008

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Human Cytosolic Hydroxysteroid Dehydrogenases of the Aldo-ketoreductase Superfamily Catalyze Reduction of Conjugated Steroids

The Journal of biological chemistry, 2009-04, Vol.284 (15), p.10013-10022

2009

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Oestradiol and mirtazapine restore the disturbed tail-temperature of oestrogen-deficient rats

European journal of pharmacology, 2003-12, Vol.482 (1), p.329-333

2003

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Tibolone is not converted by human aromatase to 7α-methyl-17α-ethynylestradiol (7α-MEE):: Analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS

Steroids, 2003-03, Vol.68 (3), p.235-243

2003

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Histological and immunohistochemical evaluation of postmenopausal endometrium after 3 weeks of treatment with tibolone, estrogen only, or estrogen plus progestagen

Fertility and sterility, 2006-08, Vol.86 (2), p.352-361

2006

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Effect of tibolone administration on central and peripheral levels of allopregnanolone and beta-endorphin in female rats

Menopause (New York, N.Y.), 2006-01, Vol.13 (1), p.57-64

2006

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Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: Evidence of progestogenic effects

Steroids, 2005-11, Vol.70 (12), p.840-845

2005

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Difference in signalling between various hormone therapies in endometrium, myometrium and upper part of the vagina

Human reproduction (Oxford), 2008-02, Vol.23 (2), p.298-305

2008

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The estrogenic component of tibolone reduces adiposity in female aromatase knockout mice

Menopause (New York, N.Y.), 2009-05, Vol.16 (3), p.582-588

2009

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Levels of Tibolone and Estradiol and their Nonsulfated and Sulfated Metabolites in Serum, Myometrium, and Vagina of Postmenopausal Women Following Treatment for 21 Days With Tibolone, Estradiol, or Estradiol Plus Medroxyprogestrone Acetate

Reproductive sciences (Thousand Oaks, Calif.), 2007-02, Vol.14 (2), p.160-168

2007

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Progesterone Inhibition of Wnt/β-Catenin Signaling in Normal Endometrium and Endometrial Cancer

Tissue-selectivity: the mechanism of action of tibolone

Estetrol prevents and suppresses mammary tumors induced by DMBA in a rat model

Metabolism of the synthetic progestogen norethynodrel by human ketosteroid reductases of the aldo–keto reductase superfamily

Human Cytosolic Hydroxysteroid Dehydrogenases of the Aldo-ketoreductase Superfamily Catalyze Reduction of Conjugated Steroids: IMPLICATIONS FOR PHASE I AND PHASE II STEROID HORMONE METABOLISM

Antioxidant effect of the active metabolites of tibolone

Progestins induce catalase activities in breast cancer cells through PRB isoform: Correlation with cell growth inhibition

Receptor profiling and endocrine interactions of tibolone

Hormonal regulation of apoptosis in breast cells and tissues

In vitro studies of tibolone in breast cells

Effect of tibolone and raloxifene on the tail temperature of oestrogen-deficient rats

Effects of tibolone on nuclear receptors in human endometrial cells

Tibolone: a compound with tissue specific inhibitory effects on sulfatase

Metabolism of estradiol, ethynylestradiol, and moxestrol in rat uterus, vagina, and aorta: influence of sex steroid treatment

Hormone replacement therapy dependent changes in breast cancer-related gene expression in breast tissue of healthy postmenopausal women

Effects of Tibolone Metabolites on Human Endometrial Cell Lines in Co-culture

Human Cytosolic Hydroxysteroid Dehydrogenases of the Aldo-ketoreductase Superfamily Catalyze Reduction of Conjugated Steroids

Oestradiol and mirtazapine restore the disturbed tail-temperature of oestrogen-deficient rats

Tibolone is not converted by human aromatase to 7α-methyl-17α-ethynylestradiol (7α-MEE):: Analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS

Histological and immunohistochemical evaluation of postmenopausal endometrium after 3 weeks of treatment with tibolone, estrogen only, or estrogen plus progestagen

Effect of tibolone administration on central and peripheral levels of allopregnanolone and beta-endorphin in female rats

Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: Evidence of progestogenic effects

Difference in signalling between various hormone therapies in endometrium, myometrium and upper part of the vagina

The estrogenic component of tibolone reduces adiposity in female aromatase knockout mice

Levels of Tibolone and Estradiol and their Nonsulfated and Sulfated Metabolites in Serum, Myometrium, and Vagina of Postmenopausal Women Following Treatment for 21 Days With Tibolone, Estradiol, or Estradiol Plus Medroxyprogestrone Acetate

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