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One dose to treat them all? – Therapeutisches Drug Monitoring zur Dosisoptimierung in der oralen Antitumortherapie

Best practice onkologie, 2023-06, Vol.18 (6), p.258-261

2023

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Microdialysis—theoretical background and recent implementation in applied life-sciences

European journal of pharmaceutical sciences, 2005-05, Vol.25 (1), p.1-24

2005

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Quantifying the impact of nevirapine-based prophylaxis strategies to prevent mother-to-child transmission of HIV-1 using the population approach

Clinical therapeutics, 2013-08, Vol.35 (8), p.e119-e120

Kloft, C

2013

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Risk of target non-attainment in obese compared to non-obese patients in calculated linezolid therapy

Clinical microbiology and infection, 2020-09, Vol.26 (9), p.1222-1228

2020

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A Review of Mixed‐Effects Models of Tumor Growth and Effects of Anticancer Drug Treatment Used in Population Analysis

CPT: pharmacometrics and systems pharmacology, 2014-05, Vol.3 (5), p.1-10

2014

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124 INVITED Considerations in PK-PD of Antibodies

European journal of cancer (1990), 2011, Vol.47, p.S31-S31

Kloft, C

2011

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In vitro pharmacodynamic models to determine the effect of antibacterial drugs

Journal of antimicrobial chemotherapy, 2010-02, Vol.65 (2), p.186-201

2010

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Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin or cisplatin in patients with advanced non-small-cell lung cancer (NSCLC)

Annals of oncology, 2016-10, Vol.27 (10), p.1895-1902

2016

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High-Dosage Fosfomycin Results in Adequate Plasma and Target-Site Exposure in Morbidly Obese and Nonobese Nonhyperfiltration Patients

Antimicrobial agents and chemotherapy, 2022-05, Vol.66 (6), p.e0230221-e0230221

2022

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Does linezolid inhibit its own metabolism? Population pharmacokinetics as a tool to explain the observed nonlinearity in both healthy volunteers and septic patients

Drug metabolism and disposition, 2007-10, Vol.35 (10), p.1816-1823

2007

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Extrapolation bayésienne de la préclinique à la clinique

Revue d'épidémiologie et de santé publique, 2021-06, Vol.69, p.S13-S13

2021

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Pharmacokinetics of Cefuroxime in Synovial Fluid

Antimicrobial agents and chemotherapy, 2017-10, Vol.61 (10)

2017

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Penetration of linezolid into synovial fluid and muscle tissue after elective arthroscopy

Journal of antimicrobial chemotherapy, 2017-10, Vol.72 (10), p.2817-2822

2017

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Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients – A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial

Contemporary clinical trials communications, 2019-09, Vol.15, p.100375-100375, Article 100375

2019

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Elimination of Doripenem during Dialysis and Pharmacokinetic Evaluation of Posthemodialysis Dosing for Patients Undergoing Intermittent Renal Replacement Therapy

Antimicrobial agents and chemotherapy, 2018-05, Vol.62 (5)

2018

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Translational Pharmacometric Evaluation of Typical Antibiotic Broad‐Spectrum Combination Therapies Against Staphylococcus Aureus Exploiting In Vitro Information

CPT: pharmacometrics and systems pharmacology, 2017-08, Vol.6 (8), p.512-522

2017

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Quantifying the Impact of Nevirapine-Based Prophylaxis Strategies To Prevent Mother-to-Child Transmission of HIV-1: a Combined Pharmacokinetic, Pharmacodynamic, and Viral Dynamic Analysis To Predict Clinical Outcomes

Antimicrobial Agents and Chemotherapy, 2011-12, Vol.55 (12), p.5529-5540

2011

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Microdialysis feasibility investigations with the non-hydrophilic antifungal voriconazole for potential applications in nonclinical and clinical settings

International journal of clinical pharmacology and therapeutics, 2010-11, Vol.48 (11), p.695-704

2010

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Effect of severity of sepsis on tissue concentrations of linezolid

Journal of antimicrobial chemotherapy, 2008-01, Vol.61 (1), p.173-176

2008

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3066 Pharmacokinetically (PK)-guided dosing of paclitaxel in combination with carboplatin in advanced non-small cell lung cancer (NSCLC) is gender dependent: Updated results of the randomized CEPAC-TDM study

European journal of cancer (1990), 2015-09, Vol.51, p.S618-S618

2015

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Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model Exchange in Drug Development

CPT: pharmacometrics and systems pharmacology, 2015-06, Vol.4 (6), p.316-319

2015

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Population pharmacokinetic modelling and simulation of single and multiple dose administration of meloxicam in cats

Journal of veterinary pharmacology and therapeutics, 2010-06, Vol.33 (3), p.277-286

2010

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In Vivo Efficacy and Pharmacokinetics of Voriconazole in an Animal Model of Dermatophytosis

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3317-3321

2007

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Population pharmacokinetic data analysis of three phase I studies of matuzumab, a humanised anti-EGFR monoclonal antibody in clinical cancer development

British journal of cancer, 2008-03, Vol.98 (5), p.900-906

2008

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Contribution of the active metabolite M1 to the pharmacological activity of tesofensine in vivo: a pharmacokinetic‐pharmacodynamic modelling approach

British journal of pharmacology, 2008-01, Vol.153 (1), p.164-174

2008

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One dose to treat them all? – Therapeutisches Drug Monitoring zur Dosisoptimierung in der oralen Antitumortherapie

Microdialysis—theoretical background and recent implementation in applied life-sciences

Quantifying the impact of nevirapine-based prophylaxis strategies to prevent mother-to-child transmission of HIV-1 using the population approach

Risk of target non-attainment in obese compared to non-obese patients in calculated linezolid therapy

A Review of Mixed‐Effects Models of Tumor Growth and Effects of Anticancer Drug Treatment Used in Population Analysis

124 INVITED Considerations in PK-PD of Antibodies

In vitro pharmacodynamic models to determine the effect of antibacterial drugs

Open-label, randomized study of individualized, pharmacokinetically (PK)-guided dosing of paclitaxel combined with carboplatin or cisplatin in patients with advanced non-small-cell lung cancer (NSCLC)

High-Dosage Fosfomycin Results in Adequate Plasma and Target-Site Exposure in Morbidly Obese and Nonobese Nonhyperfiltration Patients

Does linezolid inhibit its own metabolism? Population pharmacokinetics as a tool to explain the observed nonlinearity in both healthy volunteers and septic patients

Extrapolation bayésienne de la préclinique à la clinique

Pharmacokinetics of Cefuroxime in Synovial Fluid

Penetration of linezolid into synovial fluid and muscle tissue after elective arthroscopy

Measurement of soft tissue drug concentrations in morbidly obese and non-obese patients – A prospective, parallel group, open-labeled, controlled, phase IV, single center clinical trial

Elimination of Doripenem during Dialysis and Pharmacokinetic Evaluation of Posthemodialysis Dosing for Patients Undergoing Intermittent Renal Replacement Therapy

Translational Pharmacometric Evaluation of Typical Antibiotic Broad‐Spectrum Combination Therapies Against Staphylococcus Aureus Exploiting In Vitro Information

Quantifying the Impact of Nevirapine-Based Prophylaxis Strategies To Prevent Mother-to-Child Transmission of HIV-1: a Combined Pharmacokinetic, Pharmacodynamic, and Viral Dynamic Analysis To Predict Clinical Outcomes

Microdialysis feasibility investigations with the non-hydrophilic antifungal voriconazole for potential applications in nonclinical and clinical settings

Effect of severity of sepsis on tissue concentrations of linezolid

3066 Pharmacokinetically (PK)-guided dosing of paclitaxel in combination with carboplatin in advanced non-small cell lung cancer (NSCLC) is gender dependent: Updated results of the randomized CEPAC-TDM study

Pharmacometrics Markup Language (PharmML): Opening New Perspectives for Model Exchange in Drug Development

Population pharmacokinetic modelling and simulation of single and multiple dose administration of meloxicam in cats

In Vivo Efficacy and Pharmacokinetics of Voriconazole in an Animal Model of Dermatophytosis

Population pharmacokinetic data analysis of three phase I studies of matuzumab, a humanised anti-EGFR monoclonal antibody in clinical cancer development

Contribution of the active metabolite M1 to the pharmacological activity of tesofensine in vivo: a pharmacokinetic‐pharmacodynamic modelling approach

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