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Exosomes: improved methods to characterize their morphology, RNA content, and surface protein biomarkers

Analyst (London), 2015-10, Vol.140 (19), p.6631-6642

2015

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An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets

BMC bioinformatics, 2019-08, Vol.20 (1), p.433-433, Article 433

2019

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WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial–mesenchymal transition

The Journal of biological chemistry, 2019-04, Vol.294 (14), p.5261-5280

2019

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Induction of Wnt-inducible signaling protein-1 correlates with invasive breast cancer oncogenesis and reduced type 1 cell-mediated cytotoxic immunity: a retrospective study

PLoS computational biology, 2014-01, Vol.10 (1), p.e1003409

2014

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Extent of beta cell destruction is important but insufficient to predict the onset of type 1 diabetes mellitus

PloS one, 2008-01, Vol.3 (1), p.e1374-e1374

2008

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Data-driven learning how oncogenic gene expression locally alters heterocellular networks

Nature communications, 2022-04, Vol.13 (1), p.1986-1986, Article 1986

2022

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An empirical Bayesian approach for model-based inference of cellular signaling networks

BMC bioinformatics, 2009-11, Vol.10 (1), p.371-371, Article 371

Klinke, 2nd, David J

2009

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An in silico exploration of combining Interleukin-12 with Oxaliplatin to treat liver-metastatic colorectal cancer

BMC cancer, 2020-01, Vol.20 (1), p.26-26, Article 26

2020

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Age-corrected beta cell mass following onset of type 1 diabetes mellitus correlates with plasma C-peptide in humans

PloS one, 2011-11, Vol.6 (11), p.e26873-e26873

2011

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Interleukin-12 elicits a non-canonical response in B16 melanoma cells to enhance survival

Cell communication and signaling, 2020-05, Vol.18 (1), p.78-78, Article 78

2020

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Inferring alterations in cell-to-cell communication in HER2+ breast cancer using secretome profiling of three cell models

Biotechnology and bioengineering, 2014-09, Vol.111 (9), p.1853-1863

2014

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Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function

Pigment cell and melanoma research, 2017-03, Vol.30 (2), p.203-218

2017

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Exosomes derived from B16F0 melanoma cells alter the transcriptome of cytotoxic T cells that impacts mitochondrial respiration

The FEBS journal, 2018-03, Vol.285 (6), p.1033-1050

2018

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Cell Communication Network factor 4 promotes tumor‐induced immunosuppression in melanoma

EMBO reports, 2022-04, Vol.23 (4), p.e54127-n/a

2022

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In silico model-based inference: A contemporary approach for hypothesis testing in network biology

Biotechnology progress, 2014-11, Vol.30 (6), p.1247-1261

Klinke II, David J.

2014

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CD8(+) T cell response to adenovirus vaccination and subsequent suppression of tumor growth: modeling, simulation and analysis

BMC systems biology, 2015-06, Vol.9 (1), p.27-27, Article 27

2015

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An Unsupervised Strategy for Identifying Epithelial-Mesenchymal Transition State Metrics in Breast Cancer and Melanoma

iScience, 2020-05, Vol.23 (5), p.101080-101080, Article 101080

2020

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Identifying causal networks linking cancer processes and anti-tumor immunity using Bayesian network inference and metagene constructs

Biotechnology progress, 2016-03, Vol.32 (2), p.470-479

2016

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Head-to-Head Comparison of CCN4, DNMT3A, PTPN11, and SPARC as Suppressors of Anti-tumor Immunity

Cellular and molecular bioengineering, 2023-12, Vol.16 (5-6), p.431-442

2023

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Interlocked positive and negative feedback network motifs regulate β-catenin activity in the adherens junction pathway

Molecular biology of the cell, 2015-11, Vol.26 (22), p.4135-4148

2015

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Signal Transduction Networks in Cancer: Quantitative Parameters Influence Network Topology

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (5), p.1773-1782

KLINKE, David J

2010

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Quantifying crosstalk among interferon-γ, interleukin-12, and tumor necrosis factor signaling pathways within a TH1 cell model

Science signaling, 2012-04, Vol.5 (220), p.ra32

2012

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Inferring predominant pathways in cellular models of breast cancer using limited sample proteomic profiling

BMC cancer, 2010-06, Vol.10 (1), p.291-291, Article 291

2010

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A multiscale systems perspective on cancer, immunotherapy, and Interleukin-12

Molecular cancer, 2010-09, Vol.9 (1), p.242-242, Article 242

Klinke, 2nd, David J

2010

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Is immune checkpoint modulation a potential therapeutic option in triple negative breast cancer?

Breast cancer research : BCR, 2014-11, Vol.16 (6), p.457-457, Article 457

Klinke, 2nd, David J

2014

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Exosomes: improved methods to characterize their morphology, RNA content, and surface protein biomarkers

An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets

WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial–mesenchymal transition

Induction of Wnt-inducible signaling protein-1 correlates with invasive breast cancer oncogenesis and reduced type 1 cell-mediated cytotoxic immunity: a retrospective study

Extent of beta cell destruction is important but insufficient to predict the onset of type 1 diabetes mellitus

Data-driven learning how oncogenic gene expression locally alters heterocellular networks

An empirical Bayesian approach for model-based inference of cellular signaling networks

An in silico exploration of combining Interleukin-12 with Oxaliplatin to treat liver-metastatic colorectal cancer

Age-corrected beta cell mass following onset of type 1 diabetes mellitus correlates with plasma C-peptide in humans

Interleukin-12 elicits a non-canonical response in B16 melanoma cells to enhance survival

Inferring alterations in cell-to-cell communication in HER2+ breast cancer using secretome profiling of three cell models

Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function

Exosomes derived from B16F0 melanoma cells alter the transcriptome of cytotoxic T cells that impacts mitochondrial respiration

Cell Communication Network factor 4 promotes tumor‐induced immunosuppression in melanoma

In silico model-based inference: A contemporary approach for hypothesis testing in network biology

CD8(+) T cell response to adenovirus vaccination and subsequent suppression of tumor growth: modeling, simulation and analysis

An Unsupervised Strategy for Identifying Epithelial-Mesenchymal Transition State Metrics in Breast Cancer and Melanoma

Identifying causal networks linking cancer processes and anti-tumor immunity using Bayesian network inference and metagene constructs

Head-to-Head Comparison of CCN4, DNMT3A, PTPN11, and SPARC as Suppressors of Anti-tumor Immunity

Interlocked positive and negative feedback network motifs regulate β-catenin activity in the adherens junction pathway

Signal Transduction Networks in Cancer: Quantitative Parameters Influence Network Topology

Quantifying crosstalk among interferon-γ, interleukin-12, and tumor necrosis factor signaling pathways within a TH1 cell model

Inferring predominant pathways in cellular models of breast cancer using limited sample proteomic profiling

A multiscale systems perspective on cancer, immunotherapy, and Interleukin-12

Is immune checkpoint modulation a potential therapeutic option in triple negative breast cancer?

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