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Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (28), p.E6428-E6436

2018

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The Critical Role of the Constant Region in Thermal Stability and Aggregation of Amyloidogenic Immunoglobulin Light Chain

Biochemistry (Easton), 2010-11, Vol.49 (45), p.9848-9857

2010

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Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal

Biochemistry (Easton), 2015-01, Vol.54 (2), p.268-278

2015

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A Conservative Point Mutation in a Dynamic Antigen-binding Loop of Human Immunoglobulin λ6 Light Chain Promotes Pathologic Amyloid Formation

Journal of molecular biology, 2021-12, Vol.433 (24), p.167310-167310, Article 167310

2021

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Role of complementarity-determining regions 1 and 3 in pathologic amyloid formation by human immunoglobulin κ1 light chains

Amyloid, 2023-12, Vol.ahead-of-print (ahead-of-print), p.1-15

2023

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An additive destabilising effect of compound T60I and V122I substitutions in ATTRv amyloidosis

Amyloid, 2023-04, Vol.30 (2), p.141-152

2023

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A novel substitution of proline (P32L) destabilises β2-microglobulin inducing hereditary systemic amyloidosis

Amyloid, 2022-10, Vol.29 (4), p.255-262

2022

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Expression, purification, and in vitro cysteine-10 modification of native sequence recombinant human transthyretin

Protein expression and purification, 2007-06, Vol.53 (2), p.370-377

2007

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In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis

Amyloid, 2017-06, Vol.24 (2), p.115-122

2017

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Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal: DIRECT ANALYSIS BY FLUORESCENCE-DETECTED ANALYTICAL ULTRACENTRIFUGATION

The Journal of biological chemistry, 2008-05, Vol.283 (18), p.11887-11896

2008

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The Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal

The Journal of biological chemistry, 2008-05, Vol.283 (18), p.11887-11896

2008

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The metal-binding properties of DREAM: evidence for calcium-mediated changes in DREAM structure

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.10955-10966

2002

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The Metal-binding Properties of DREAM

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.10955-10966

2002

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Changes in structure and stability of calbindin-D28K upon calcium binding

Analytical biochemistry, 2004-11, Vol.334 (1), p.97-105

2004

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Changes in structure and stability of calbindin-D 28K upon calcium binding

Analytical biochemistry, 2004-11, Vol.334 (1), p.97-105

2004

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Changes in structure and stability of calbindin-D(28K) upon calcium binding

Analytical biochemistry, 2004-11, Vol.334 (1), p.97-105

2004

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Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited

Biophysical journal, 2012-06, Vol.102 (11), p.2585-2594

2012

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Interactions between fatty acids and α-synuclein

Journal of lipid research, 2006-08, Vol.47 (8), p.1714-1724

2006

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Photophysics of ANS III: Circular dichroism of ANS and anilinonaphthalene in I-FABP

Biophysical chemistry, 2007, Vol.125 (1), p.24-31

2007

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The circulating molecular chaperone clusterin interacts with amyloidogenic transthyretin oligomers and modulates amyloid formation

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein

Biophysical journal, 2010-01, Vol.98 (3), p.238a-238a

2010

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Human Liver Fatty Acid Binding Protein: Solution Structure and Ligand Binding

Biophysical journal, 2009-02, Vol.96 (3), p.600a-600a

2009

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Photophysics of ANS. I. Protein–ANS complexes: Intestinal fatty acid binding protein and single- trp mutants

Biophysical chemistry, 2007, Vol.125 (1), p.1-12

2007

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The effects of hexanol on Galpha(i) subunits of heterotrimeric G proteins

Anesthesia and analgesia, 2004-03, Vol.98 (3), p.660-667

2004

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The Effects of Hexanol on G??i Subunits of Heterotrimeric G Proteins

Anesthesia and analgesia, 2004-03, p.660-667

2004

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Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease

The Critical Role of the Constant Region in Thermal Stability and Aggregation of Amyloidogenic Immunoglobulin Light Chain

Cooperative Stabilization of Transthyretin by Clusterin and Diflunisal

A Conservative Point Mutation in a Dynamic Antigen-binding Loop of Human Immunoglobulin λ6 Light Chain Promotes Pathologic Amyloid Formation

Role of complementarity-determining regions 1 and 3 in pathologic amyloid formation by human immunoglobulin κ1 light chains

An additive destabilising effect of compound T60I and V122I substitutions in ATTRv amyloidosis

A novel substitution of proline (P32L) destabilises β2-microglobulin inducing hereditary systemic amyloidosis

Expression, purification, and in vitro cysteine-10 modification of native sequence recombinant human transthyretin

In vitro co-expression of human amyloidogenic immunoglobulin light and heavy chain proteins: a relevant cell-based model of AL amyloidosis

Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal: DIRECT ANALYSIS BY FLUORESCENCE-DETECTED ANALYTICAL ULTRACENTRIFUGATION

The Modulation of Transthyretin Tetramer Stability by Cysteine 10 Adducts and the Drug Diflunisal

The metal-binding properties of DREAM: evidence for calcium-mediated changes in DREAM structure

The Metal-binding Properties of DREAM

Changes in structure and stability of calbindin-D28K upon calcium binding

Changes in structure and stability of calbindin-D 28K upon calcium binding

Changes in structure and stability of calbindin-D(28K) upon calcium binding

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein: Fatty Acid Binding Revisited

Interactions between fatty acids and α-synuclein

Photophysics of ANS III: Circular dichroism of ANS and anilinonaphthalene in I-FABP

The circulating molecular chaperone clusterin interacts with amyloidogenic transthyretin oligomers and modulates amyloid formation

Solution Structure and Backbone Dynamics of Human Liver Fatty Acid Binding Protein

Human Liver Fatty Acid Binding Protein: Solution Structure and Ligand Binding

Photophysics of ANS. I. Protein–ANS complexes: Intestinal fatty acid binding protein and single- trp mutants

The effects of hexanol on Galpha(i) subunits of heterotrimeric G proteins

The Effects of Hexanol on G??i Subunits of Heterotrimeric G Proteins

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