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Striking Effect of Hydroxamic Acid Substitution on the Phosphodiesterase Type 4 (PDE4) and TNFα Inhibitory Activity of Two Series of Rolipram Analogues: Implications for a New Active Site Model of PDE4

Journal of medicinal chemistry, 1998-01, Vol.41 (3), p.266-270

1998

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CP-71,362: A Pentapeptide Renin Inhibitor Selective for the Canine Enzyme

Clinical and experimental hypertension (1993), 1994, Vol.16 (4), p.507-533

1994

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A short, stereoselective synthesis of the lactone precursor to 2R,4S,5S hydroxyethylene dipeptide isosteres

Journal of organic chemistry, 1986-12, Vol.51 (25), p.4828-4833

1986

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Discovery of inhibitors of human renin with high oral bioavailability

Advances in experimental medicine and biology, 1995, Vol.362, p.167

1995

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On the methanolysis of KBBL, an immunostimulant derived from ascorbic acid

Tetrahedron, 1993-08, Vol.49 (34), p.7437-7444

1993

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Striking example of a contact chloride ion pair with bridging water molecules in the solid state

Journal of the American Chemical Society, 1992-06, Vol.114 (12), p.4945-4946

1992

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CP-71,362, an unusually potent inhibitor of rat and dog renin

Bioorganic & medicinal chemistry letters, 1994-02, Vol.4 (4), p.589-592

1994

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A convenient synthesis of 3,6-disubstituted 3,6-diazabicyclo[3.2.2]nonanes and 3,6-diazabicyclo[3.2.1]octanes

Journal of organic chemistry, 1988-02, Vol.53 (4), p.896-899

1988

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Synthesis and antibacterial activity of 2,3-dehydroofloxacin

Journal of heterocyclic chemistry, 1990-07, Vol.27 (5), p.1509-1511

1990

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Synthesis of 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo[3,2,1-ij]quinoline-5-carboxylic acid

Journal of heterocyclic chemistry, 1988-09, Vol.25 (5), p.1567-1569

1988

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Isoaromatization of 4-Alkylidene-3-oxo-1- cyclohexene-1-carboxylates. Convenient Synthesis of Methyl 4-Alkyl-3-hydroxybenzoates

Journal of organic chemistry, 1996-07, Vol.61 (14), p.4806-4809

1996

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Novel [3+2] and [3+3] 4-quinolone annulations by tandem Claisen-Cope amidoalkylation reaction

Journal of organic chemistry, 1992-12, Vol.57 (25), p.6991-6995

1992

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Novel [3 + 2] nd [3 + 3] 4-quinolone annulations by tandem Claisen-Cope-amidoalkylation reaction

Journal of organic chemistry, 1992, Vol.57 (25), p.6991-6995

1992

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Total synthesis of lycopodium alkaloids: (.+-.)-lycopodine, (.+-.)-lycodine, and (.+-.)-lycodoline

Journal of the American Chemical Society, 1982-02, Vol.104 (4), p.1054-1068

1982

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ChemInform Abstract: Isoaromatization of 4-Alkylidene-3-oxo-1-cyclohexene-1-carboxylates. Convenient Synthesis of Methyl 4-Alkyl-3-hydroxybenzoates

ChemInform, 1996-11, Vol.27 (46), p.no-no

1996

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ChemInform Abstract: Methanolysis of KBBL, an Immunostimulant Derived from Ascorbic Acid

ChemInform, 1993-12, Vol.24 (50), p.no-no

1993

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ChemInform Abstract: Synthesis and Antibacterial Activity of 2,3-Dehydroofloxacin

ChemInform, 1991-01, Vol.22 (1), p.no-no

1991

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Total synthesis of (.+-.)-lycodoline

Journal of the American Chemical Society, 1981-01, Vol.103 (1), p.222-223

1981

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ChemInform Abstract: Synthesis of 8,9‐Difluoro‐2‐methyl‐6‐oxo‐1,2‐dihydropyrrolo(3,2,1‐ij)quinoline‐5‐carboxylic Acid (IX)

ChemInform, 1989-07, Vol.20 (28), p.no-no

1989

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ChemInform Abstract: A Convenient Synthesis of 3,6‐Disubstituted 3,6‐Diazabicyclo(3.2.2)nonanes and 3,6‐Diazabicyclo(3.2.1)octanes

ChemInform, 1988-07, Vol.19 (30), p.no-no

1988

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ChemInform Abstract: A Short, Stereoselective Synthesis of the Lactone Precursor to 2R,4S,5S‐Hydroxyethylene Dipeptide Isosters

ChemInform, 1987-07, Vol.18 (30), p.no-no

1987

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ChemInform Abstract: Novel (3 + 2)- and (3 + 3)-4-Quinolone Annulations by Tandem Claisen-Cope Amidoalkylation Reaction

ChemInform, 1993-05, Vol.24 (19), p.no-no

1993

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RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder

Molecular psychiatry, 2014-11, Vol.19 (11), p.1179-1185

2014

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Functional Analysis of Genetic Variation in Catechol-O-Methyltransferase ( COMT): Effects on mRNA, Protein, and Enzyme Activity in Postmortem Human Brain

American journal of human genetics, 2004-11, Vol.75 (5), p.807-821

2004

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ILCOR Scientific Knowledge Gaps and Clinical Research Priorities for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: A Consensus Statement

Circulation (New York, N.Y.), 2018-05, Vol.137 (22), p.e802-e819

2018

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Striking Effect of Hydroxamic Acid Substitution on the Phosphodiesterase Type 4 (PDE4) and TNFα Inhibitory Activity of Two Series of Rolipram Analogues: Implications for a New Active Site Model of PDE4

CP-71,362: A Pentapeptide Renin Inhibitor Selective for the Canine Enzyme

A short, stereoselective synthesis of the lactone precursor to 2R,4S,5S hydroxyethylene dipeptide isosteres

Discovery of inhibitors of human renin with high oral bioavailability

On the methanolysis of KBBL, an immunostimulant derived from ascorbic acid

Striking example of a contact chloride ion pair with bridging water molecules in the solid state

CP-71,362, an unusually potent inhibitor of rat and dog renin

A convenient synthesis of 3,6-disubstituted 3,6-diazabicyclo[3.2.2]nonanes and 3,6-diazabicyclo[3.2.1]octanes

Synthesis and antibacterial activity of 2,3-dehydroofloxacin

Synthesis of 8,9-difluoro-2-methyl-6-oxo-1,2-dihydropyrrolo[3,2,1-ij]quinoline-5-carboxylic acid

Isoaromatization of 4-Alkylidene-3-oxo-1- cyclohexene-1-carboxylates. Convenient Synthesis of Methyl 4-Alkyl-3-hydroxybenzoates

Novel [3+2] and [3+3] 4-quinolone annulations by tandem Claisen-Cope amidoalkylation reaction

Novel [3 + 2] nd [3 + 3] 4-quinolone annulations by tandem Claisen-Cope-amidoalkylation reaction

Total synthesis of lycopodium alkaloids: (.+-.)-lycopodine, (.+-.)-lycodine, and (.+-.)-lycodoline

ChemInform Abstract: Isoaromatization of 4-Alkylidene-3-oxo-1-cyclohexene-1-carboxylates. Convenient Synthesis of Methyl 4-Alkyl-3-hydroxybenzoates

ChemInform Abstract: Methanolysis of KBBL, an Immunostimulant Derived from Ascorbic Acid

ChemInform Abstract: Synthesis and Antibacterial Activity of 2,3-Dehydroofloxacin

Total synthesis of (.+-.)-lycodoline

ChemInform Abstract: Synthesis of 8,9‐Difluoro‐2‐methyl‐6‐oxo‐1,2‐dihydropyrrolo(3,2,1‐ij)quinoline‐5‐carboxylic Acid (IX)

ChemInform Abstract: A Convenient Synthesis of 3,6‐Disubstituted 3,6‐Diazabicyclo(3.2.2)nonanes and 3,6‐Diazabicyclo(3.2.1)octanes

ChemInform Abstract: A Short, Stereoselective Synthesis of the Lactone Precursor to 2R,4S,5S‐Hydroxyethylene Dipeptide Isosters

ChemInform Abstract: Novel (3 + 2)- and (3 + 3)-4-Quinolone Annulations by Tandem Claisen-Cope Amidoalkylation Reaction

RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder

Functional Analysis of Genetic Variation in Catechol-O-Methyltransferase ( COMT): Effects on mRNA, Protein, and Enzyme Activity in Postmortem Human Brain

ILCOR Scientific Knowledge Gaps and Clinical Research Priorities for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: A Consensus Statement

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