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Review: Mechanisms of How the Intestinal Microbiota Alters the Effects of Drugs and Bile Acids

Drug metabolism and disposition, 2015-10, Vol.43 (10), p.1505-1521

2015

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Xenobiotic, bile acid, and cholesterol transporters: function and regulation

Pharmacological reviews, 2010-03, Vol.62 (1), p.1

2010

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Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver

PloS one, 2012-07, Vol.7 (7), p.e39006

2012

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Molecular Regulation of Bile Acid Homeostasis

Drug metabolism and disposition, 2022-04, Vol.50 (4), p.425-455

2022

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Diurnal variation of hepatic antioxidant gene expression in mice

PloS one, 2012-08, Vol.7 (8), p.e44237

2012

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Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver

Toxicology and applied pharmacology, 2010-04, Vol.244 (1), p.57-65

2010

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RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome

Biochimica et biophysica acta, 2016-09, Vol.1859 (9), p.1198-1217

2016

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Oxidative stress and the pathogenesis of cholestasis

Seminars in liver disease, 2010-05, Vol.30 (2), p.195

2010

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Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption

Toxicological sciences, 2011-10, Vol.123 (2), p.590-600

2011

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Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice

Drug metabolism and disposition, 2012-07, Vol.40 (7), p.1366

2012

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Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice

PloS one, 2013-03, Vol.8 (3), p.e59122-e59122

2013

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Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver-insights into mechanisms of hepatic steatosis

PloS one, 2014-02, Vol.9 (2), p.e88584-e88584

2014

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Dose-Response of Five Bile Acids on Serum and Liver Bile Acid Concentrations and Hepatotoxicty in Mice

Toxicological sciences, 2011-10, Vol.123 (2), p.359-367

2011

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RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice

Drug metabolism and disposition, 2015-10, Vol.43 (10), p.1572-1580

2015

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Structure, Function, Expression, Genomic Organization, and Single Nucleotide Polymorphisms of Human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) Efflux Transporters

International Journal of Toxicology, 2006-07, Vol.25 (4), p.231-259

2006

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Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

Hepatology (Baltimore, Md.), 2012-09, Vol.56 (3), p.1034-1043

2012

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Tissue distribution and ontogeny of organic cation transporters in mice

Drug metabolism and disposition, 2006-03, Vol.34 (3), p.477

2006

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Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms

Toxicology and applied pharmacology, 2020-07, Vol.399, p.115039, Article 115039

2020

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Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters

PloS one, 2011-02, Vol.6 (2), p.e16683

2011

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Effect of Gender and Various Diets on Bile Acid Profile and Related Genes in Mice

Drug metabolism and disposition, 2021-01, Vol.49 (1), p.62-71

2021

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Screening of natural compounds as activators of the keap1-nrf2 pathway

Planta medica, 2014-01, Vol.80 (1), p.97

2014

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Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor

PloS one, 2018-08, Vol.13 (8), p.e0200004

2018

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Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P450 mRNAs in Mice

Toxicological sciences, 2011-12, Vol.124 (2), p.261-277

2011

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Nrf2 activation prevents cadmium-induced acute liver injury

Toxicology and applied pharmacology, 2012-08, Vol.263 (1), p.14-20

2012

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Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics

Drug metabolism and disposition, 2016-02, Vol.44 (2), p.262-274

2016

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Review: Mechanisms of How the Intestinal Microbiota Alters the Effects of Drugs and Bile Acids

Xenobiotic, bile acid, and cholesterol transporters: function and regulation

Effect of graded Nrf2 activation on phase-I and -II drug metabolizing enzymes and transporters in mouse liver

Molecular Regulation of Bile Acid Homeostasis

Diurnal variation of hepatic antioxidant gene expression in mice

Nrf2 the rescue: Effects of the antioxidative/electrophilic response on the liver

RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome

Oxidative stress and the pathogenesis of cholestasis

Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption

Coordinated regulation of hepatic phase I and II drug-metabolizing genes and transporters using AhR-, CAR-, PXR-, PPARα-, and Nrf2-null mice

Genetic activation of Nrf2 protects against fasting-induced oxidative stress in livers of mice

Effect of diet on expression of genes involved in lipid metabolism, oxidative stress, and inflammation in mouse liver-insights into mechanisms of hepatic steatosis

Dose-Response of Five Bile Acids on Serum and Liver Bile Acid Concentrations and Hepatotoxicty in Mice

RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice

Structure, Function, Expression, Genomic Organization, and Single Nucleotide Polymorphisms of Human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) Efflux Transporters

Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice

Tissue distribution and ontogeny of organic cation transporters in mice

Elucidation of OATP1B1 and 1B3 transporter function using transgenic rodent models and commonly known single nucleotide polymorphisms

Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters

Effect of Gender and Various Diets on Bile Acid Profile and Related Genes in Mice

Screening of natural compounds as activators of the keap1-nrf2 pathway

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor

Tissue Distribution and Gender-Divergent Expression of 78 Cytochrome P450 mRNAs in Mice

Nrf2 activation prevents cadmium-induced acute liver injury

Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics

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