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Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients

Critical care (London, England), 2017-08, Vol.21 (1), p.213-213, Article 213

2017

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Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans

American journal of physiology. Heart and circulatory physiology, 2008-01, Vol.294 (1), p.H41-H49

2008

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Selepressin, a novel selective vasopressin V 1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients

Critical care (London, England), 2017-08, Vol.21 (1), p.213

2017

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Differential Extracellular Signal‐Regulated Kinases 1 and 2 Activation by the Angiotensin Type 1 Receptor Supports Distinct Phenotypes of Cardiac Myocytes

Basic & clinical pharmacology & toxicology, 2007-05, Vol.100 (5), p.296-301

2007

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The Angiotensin Type 1 Receptor Activates Extracellular Signal‐Regulated Kinases 1 and 2 by G Protein‐Dependent and ‐Independent Pathways in Cardiac Myocytes and Langendorff‐Perfused Hearts

Basic & clinical pharmacology & toxicology, 2007-05, Vol.100 (5), p.289-295

2007

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Pharmacological Modulation of Gap Junction Function with the Novel Compound Rotigaptide: A Promising New Principle for Prevention of Arrhythmias

Basic & clinical pharmacology & toxicology, 2007-10, Vol.101 (4), p.215-230

2007

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Novel Long-Acting Lipidated Interleukin-22 Reduces Body Weight and Improves Glucose Control in Mice

Obesity (Silver Spring, Md.), 2023-11, Vol.31, p.27-28

2023

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ZP123 Increases Gap Junctional Conductance and Prevents Reentrant Ventricular Tachycardia During Myocardial Ischemia in Open Chest Dogs

Journal of cardiovascular electrophysiology, 2003-05, Vol.14 (5), p.510-520

2003

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A Selective V(1A) Receptor Agonist, Selepressin, Is Superior to Arginine Vasopressin and to Norepinephrine in Ovine Septic Shock

Critical care medicine, 2016-01, Vol.44 (1), p.23

2016

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Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial

Annals of the American Thoracic Society, 2018-02, Vol.15 (2), p.250-257

2018

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Pharmacological stimulation of cardiac gap junction coupling does not affect ischemia-induced focal ventricular tachycardia or triggered activity in dogs

American journal of physiology. Heart and circulatory physiology, 2005-02, Vol.288 (2), p.H511-H516

2005

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Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

American journal of physiology. Regulatory, integrative and comparative physiology, 2010-06, Vol.298 (6), p.R1560-R1570

2010

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Increasing Gap Junctional Coupling: A Tool for Dissecting the Role of Gap Junctions

The Journal of membrane biology, 2007-03, Vol.216 (1), p.23-35

2007

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Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123)

Journal of molecular and cellular cardiology, 2006-06, Vol.40 (6), p.790-798

2006

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Pharmacological stimulation of cardiac gap junction coupling does not affect ischemia-induced focal ventricular tachycardia or triggered activity in dogs

American journal of physiology. Heart and circulatory physiology, 2005-02, Vol.57 (2), p.H511-H516

2005

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A Selective V1A Receptor Agonist, Selepressin, Is Superior to Arginine Vasopressin and to Norepinephrine in Ovine Septic Shock

Critical care medicine, 2016-01, Vol.44 (1), p.23-31

2016

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Anti-arrhythmic Peptide N-3-(4-Hydroxyphenyl)propionyl Pro-Hyp-Gly-Ala-Gly-OH Reduces Dispersion of Action Potential Duration During Ischemia/Reperfusion in Rabbit Hearts

Journal of cardiovascular pharmacology, 2002-11, Vol.40 (5), p.770-779

2002

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62: SELEPRESSIN, A NOVEL SELECTIVE VASOPRESSIN V1A AGONIST, REDUCES NOREPINEPHRINE REQUIREMENTS AND SHORTENS DURATION OF ORGAN DYSFUNCTION IN SEPTIC SHOCK PATIENTS

Critical care medicine, 2012-12, Vol.40, p.1-328

2012

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Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure

Journal of intensive care, 2016-03, Vol.4 (24), p.24-24, Article 24

2016

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Metabolic and cardiac changes in high cholesterol–fructose-fed rats

Journal of pharmacological and toxicological methods, 2010-05, Vol.61 (3), p.292-296

2010

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123: EARLY ADMINISTRATION OF THE SELECTIVE V1A RECEPTOR AGONIST SELEPRESSIN IS SUPERIOR TO ARGININE VASOPRESSIN OR NOREPINEPHRINE IN A SHEEP MODEL OF SEPTIC SHOCK

Critical care medicine, 2012-12, Vol.40, p.1-328

2012

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Pharmacological characterization of the new stable antiarrhythmic peptide analog Ac-D-Tyr-D-Pro-D-Hyp-Gly-D-Ala-Gly-NH2 (ZP123): in vivo and in vitro studies

The Journal of pharmacology and experimental therapeutics, 2003-09, Vol.306 (3), p.1191

2003

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Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

American journal of physiology. Regulatory, integrative and comparative physiology, 2010, Vol.67 (6)

2010

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Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans

American journal of physiology. Heart and circulatory physiology, 2008, Vol.63 (1)

2008

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Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients

Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans

Selepressin, a novel selective vasopressin V 1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients

Differential Extracellular Signal‐Regulated Kinases 1 and 2 Activation by the Angiotensin Type 1 Receptor Supports Distinct Phenotypes of Cardiac Myocytes

The Angiotensin Type 1 Receptor Activates Extracellular Signal‐Regulated Kinases 1 and 2 by G Protein‐Dependent and ‐Independent Pathways in Cardiac Myocytes and Langendorff‐Perfused Hearts

Study protocol of a randomised, double-blind, placebo-controlled, two-arm parallel-group, multi-centre phase 3 pivotal trial to investigate the efficacy and safety of recombinant human alkaline phosphatase for treatment of patients with sepsis-associated acute kidney injury

Pharmacological Modulation of Gap Junction Function with the Novel Compound Rotigaptide: A Promising New Principle for Prevention of Arrhythmias

Novel Long-Acting Lipidated Interleukin-22 Reduces Body Weight and Improves Glucose Control in Mice

ZP123 Increases Gap Junctional Conductance and Prevents Reentrant Ventricular Tachycardia During Myocardial Ischemia in Open Chest Dogs

A Selective V(1A) Receptor Agonist, Selepressin, Is Superior to Arginine Vasopressin and to Norepinephrine in Ovine Septic Shock

Rationale and Design of an Adaptive Phase 2b/3 Clinical Trial of Selepressin for Adults in Septic Shock. Selepressin Evaluation Programme for Sepsis-induced Shock-Adaptive Clinical Trial

Pharmacological stimulation of cardiac gap junction coupling does not affect ischemia-induced focal ventricular tachycardia or triggered activity in dogs

Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

Increasing Gap Junctional Coupling: A Tool for Dissecting the Role of Gap Junctions

Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123)

Pharmacological stimulation of cardiac gap junction coupling does not affect ischemia-induced focal ventricular tachycardia or triggered activity in dogs

A Selective V1A Receptor Agonist, Selepressin, Is Superior to Arginine Vasopressin and to Norepinephrine in Ovine Septic Shock

Anti-arrhythmic Peptide N-3-(4-Hydroxyphenyl)propionyl Pro-Hyp-Gly-Ala-Gly-OH Reduces Dispersion of Action Potential Duration During Ischemia/Reperfusion in Rabbit Hearts

62: SELEPRESSIN, A NOVEL SELECTIVE VASOPRESSIN V1A AGONIST, REDUCES NOREPINEPHRINE REQUIREMENTS AND SHORTENS DURATION OF ORGAN DYSFUNCTION IN SEPTIC SHOCK PATIENTS

Designing phase 3 sepsis trials: application of learned experiences from critical care trials in acute heart failure

Metabolic and cardiac changes in high cholesterol–fructose-fed rats

123: EARLY ADMINISTRATION OF THE SELECTIVE V1A RECEPTOR AGONIST SELEPRESSIN IS SUPERIOR TO ARGININE VASOPRESSIN OR NOREPINEPHRINE IN A SHEEP MODEL OF SEPTIC SHOCK

Pharmacological characterization of the new stable antiarrhythmic peptide analog Ac-D-Tyr-D-Pro-D-Hyp-Gly-D-Ala-Gly-NH2 (ZP123): in vivo and in vitro studies

Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans

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